The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases

The SIB Swiss Institute of Bioinformatics (www.isb-sib.ch) provides world-class bioinformatics databases, software tools, services and training to the international life science community in academia and industry. These solutions allow life scientists to turn the exponentially growing amount of data into knowledge. Here, we provide an overview of SIB's resources and competence areas, with a strong focus on curated databases and SIB's most popular and widely used resources. In particular, SIB's Bioinformatics resource portal ExPASy features over 150 resources, including UniProtKB/Swiss-Prot, ENZYME, PROSITE, neXtProt, STRING, UniCarbKB, SugarBindDB, SwissRegulon, EPD, arrayMap, Bgee, SWISS-MODEL Repository, OMA, OrthoDB and other databases, which are briefly described in this article

Minimally invasive plate fixation of the tibia

The treatment of fractures of the distal third of the tibia has evolved with the development of improved imaging and surgical techniques. The outcome of treatment using conventional fixation is poor. We report a study on indirect reduction in 26 patients. All cases achieved radiological union and full weight bearing. The good to excellent results suggest that this method should be considered in metaphyseal fractures where intra-medullary nails are not suitable