Human tolerogenic dendritic cells produce IL-35 in the absence of other IL-12 family members

Nephrolog

Phagocytosis of apoptotic or necrotic cells differentially regulates the transcriptional expression of IL-12 family members in dendritic cells

Nephrolog

Subsets of human type 2 macrophages show differential capacity to produce reactive oxygen species

Nephrolog

Subsets of alternatively activated human macrophages show differential capacity to produce reactive oxygen species

Nephrolog

Dexamethasone increases ROS production and T cell suppressive capacity by anti-inflammatory macrophages

Nephrolog

Anti-inflammatory macrophages induce regulatory T cells by producing reactive oxygen species

Nephrolog

Percorsi semantici e rappresentativi in Between the Acts di Virginia Woolf

L'opera viene analizzata attraverso una breve introduzione sulla biografia dell'autrice Virginia Woolf per poi mettere in luce le analogie tra la struttura del romanzo e il device teatrale. Seguiranno un’analisi del contesto e dei personaggi, soprattutto quelli di particolare rilievo, e considerazioni sull’omosessualità che riguarda alcune di queste figure, da mettere a confronto con la bisessualità (sostanzialmente platonica) della Woolf

Circadian rhythm disruption as a link between Attention-Deficit/Hyperactivity Disorder and obesity?

Objective: Patients with Attention-Deficit/Hyperactivity Disorder (ADHD) have a high prevalence of obesity. This is the first study to investigate whether circadian rhythmdisruption is a mechanismlinking ADHD symptoms to obesity. Methods: ADHD symptoms and two manifestations of circadian rhythmdisruption: sleep problems and an unstable eating pattern (skipping breakfast and binge eating later in the day) were assessed in participants with obesity (n= 114), controls (n= 154), and adult ADHD patients (n= 202). Results: Participants with obesity had a higher prevalence of ADHD symptoms and short sleep on free days as compared to controls, but a lower prevalence of ADHD symptoms, short sleep on free days, and an unstable eating pattern as compared to ADHD patients.We found that participants with obesity had a similar prevalence rate of an unstable eating pattern when compared to controls.Moreover,mediation analyses showed that both sleep duration and an unstable eating pattern mediated the association between ADHD symptoms and body mass index (BMI). Conclusion: Our study supports the hypothesis that circadian rhythm disruption is a mechanism linking ADHD symptoms to obesity. Further research is needed to determine if treatment of ADHD and circadian rhythm disruption is effective in the prevention and treatment of obesity in patients with obesity and/or ADHD

Kidney injury molecule-1 staining in renal allograft biopsies 10 days after transplantation is inversely correlated with functioning proximal tubular epithelial cells

Immunopathology of vascular and renal diseases and of organ and celltransplantatio