101 research outputs found

    Numerical model of ultrasonic multi-channel data transfer for servicing subsea production complex

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    Various researchers focused on different problems, and we can conclude that a single effective communication design with a specific algorithm that could be used in all types of underwater channels was not found. The design of the transmission is highly dependent on the conditions of the canal, as various schemes are used in shallow and deep water, and various algorithms in turbulent and calm waters. The type of channel alignment also depends on parameters such as channel estimation and coding. The ever-growing demand for bandwidth, efficiency, spatial diversity and the performance of underwater acoustic communications has opened the door to using Multiple Input Multiple Output (MIMO) technology. In this paper, we propose a method of ultrasonic data transmission under water based on the MIMO technology (Many emitters, many receivers, or MIMO - Multilpe Input - Multiple Output). This approach will allow for multi-channel data transmission in water and significantly increase the speed of information transfer

    Hydrobionts of a freshwater oil-polluted northern lake: bioaccumulation of heavy metals in fish and the rate of ecosystem recovery

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    The response of phytoplankton, zooplankton, benthic and fish community structure to one of the biggest oil spill in history of Komi Republic (north-west part of Russia) was investigated using data from a long-term survey off the polluted lake. The characteristics of aquatic freshwater communities observed in the study area 10, 11 and 22 years after the spill (1994) were compared to find out the rate of natural recovery of the ecosystem after oil decontamination of bottom sediments. The concentrations of fifteen trace metals (Al, Cr, Fe, Co, Ni, Cu, Zn, As, Mo, Cd, Sb, Pb, U, Bi, Th) were analyzed in the tissues (muscle) of three fish species. The concentrations of Al (3-309 mg/kg), Cr (0,1-3,71 mg/kg), Fe (8,6-317 mg/kg), and Cu (0,09-99 mg/kg) in fishes from polluted lake resulted in most cases higher than reference thresholds. Quantitative and qualitative indicators of aquatic invertebrates from polluted lake reach those one of unpolluted lake but do not fully recover 22 years after the spill, despite that oil concentration in water column and in bottom sediments was lower than reference tresholds. We conclude that natural recovery rate of aquatic freshwater ecosystems in northern regions after oil pollution is extremely low. The purification of water and bottom sediments of oil-polluted northern water bodies is necessary for stimulation of ecosystem restoration

    Personnel Cooperation Between University and Industrial Partners in the Context of Youth Career Development

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    The article has a research, practice-oriented nature and analyzes the problems of professional development and building a career trajectory of graduates through the prism of the personnel partnership of university and the business community. The purpose of the article is to explore the personnel cooperation between university and industrial partners in the context of professional development tracks and, in the light of this, develop a cyclogram of youth career development.The article presents the results of the study of factors influencing the formation of a career trajectory from the position of students of Orenburg State University (2022). The practice of implementing the formats of personnel partnership of the university and employers of Orenburg State University, including various activities within the framework of building the trajectory of professional and career development of a future specialist, is analyzed.The authors propose recommendations for the development of a cyclogram of students’ career development, improvement of the efficiency of interaction between the university and personnel partners by creating a student association of professional development focused on enhancement of career guidance activities at university, identifying creative, scientific, and entrepreneurial potential of students, developing skills necessary to increase competitiveness in the labor market, assistance in career planning and building of university students and graduates

    Antithrombotic Therapy and the Nearest Forecast of Pulmonary Embolism in Rutine Clinical Practice (Data of the Regional Vascular Center of the Ryazan Region)

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    Aim. To perform the analysis of antithrombotic therapy and immediate prognosis in patients with pulmonary embolism (PE) in routine clinical practice.Materials and methods. During 13 months of follow-up (2018-2019) within the framework of the Russian SIRENA registry, the study included patients (n=103) with verified PE who were hospitalized at the regional vascular center. Main results. Thrombolytic therapy was performed in 63 patients (61.2% of the sample), of which 48 (76.2%) had no indications. In these cases, the most common reason for performance was the results of the PESI score (n=17) and/or a significant amount of damage to the pulmonary artery (n=10) and/or severe shortness of breath (n=3) and/or the presence of a thrombus in the right parts of the heart or deep veins of the lower extremities (n=2), in addition, in a number of medical records, the cause is indicated as “for health reasons” (n=6) or there were no data (n=10). Patients who underwent thrombolysis had a larger volume of pulmonary lesions, more pronounced signs of respiratory failure and overload of the right heart, as well as a shorter duration of clinical manifestations. Anticoagulant therapy was used in 94.2% of cases, of which 90.3% of patients used parenteral forms at the start, then direct oral anticoagulants were mainly used, the frequency of warfarin prescription was only 5.8% of cases. Bleeding was registered in 19.4% of patients (significant – in 11.7%). PE recurrence after diagnosis and initiation of therapy was observed in 4 cases (3.9%). Hospital mortality was 9.7%. Predictors of poor prognosis were hospitalization with a different diagnosis (risk ratio [RR] 16.2; p=0.001), advanced age (RR 10.1; p=0.028), unstable hemodynamics (RR 7.6; p=0.002), chronic kidney disease C3- 5 (RR 5.6; p=0.03), history of stroke (RR 5.3; p=0.016) and chronic heart failure (RR 3.9; p=0.035).Conclusion. In modern clinical practice, the indications for thrombolysis often differ from those recommended, which leads to an increase in the number of bleeding and leveling of the positive effect on the prognosis. Factors such as advanced age, chronic heart failure and atrial fibrillation, stroke, chronic kidney disease, hemodynamic instability, hospitalizations with a different primary diagnosis, and the need for oxygen therapy increase the risk of early mortality

    New opportunities for identifying the risk of cardiovascular events in young people: the role of familial hypercholesterolemia

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    A search was made for publications on modern methods for determining cardiovascular risk in young people with positive family history for early cardiovascular events. The use of various screening options allows timely identification of patients with heterozygous familial hypercholesterolemia who have a high cardiovascular risk. The most effective method is cascade screening. Cardiovascular risk assessment systems that include a family history of early cardiovascular events and lipid profiles in individuals under 40 years of age provide prevention of atherosclerosis. In the diagnosis of risk, the lipoprotein (a) is of particular clinical importance, elevated concentrations of which are associated with a high risk of vascular damage and an unfavorable course of atherosclerosis

    HEREDITARY INTRAVENTRICULAR CONDUCTION DISORDERS IN THE FAMILY FROM KRASNOYARSK

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    Pedigree of the family from Krasnoyarsk city with hereditary disorders of intracardiac conduction was studied. The diagnosis of each family member was verified by electrocardiography (ECG), echocardiography , bicycle ergometry , ECG Holter monitoring. The family 10-year follow-up showed familial aggregation of intracardiac conduction disorders in grandson, niece, son of the proband niece, ie, in the III-degree relatives. Family history of III-degree relatives with intracardiac conduction disorders and discordant pathology is identified

    Effect of genetic specifics of patients on myocardial contractility after acute myocardial infarction: a literature review

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    In this literature review, we analyzed studies on the influence of genetic specifics of patients on the restoration of myocardial contractility after acute myocardial infarction. Data on the influence of genetic characteristics on the myocardial repair, remodeling process, and the restoration of cardiac contractility are presented. The use of genetic methods in the examination of patients and further consideration of individual characteristics when prescribing therapy will make it possible to implement a personalized approach to each patient. This will improve the effectiveness of treatment and the disease prognosis

    Genetic factors in the development of pulmonary embolism

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    The article presents a literature review on the study of the relationship of FGA, FGB, F2, F5, PAI, ITGA2 gene polymorphisms with the development of pulmonary embolism (PE). We concluded that genetic factors in the development of PE are to a greater extent mutations in the F2, F5, PAI, ITGA2 genes. There is a positive correlation between the presence of combined genetic mutations and the development of PE. The study of allelic polymorphism of hemostasis genes makes it possible to predict coagulation system disorders, including PE

    Pleiotropic effect of the ABCA1 rs2230806 polymorphism in cardiovascular diseases: a literature review

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    Cerebrovascular accident (CVA) in patients with various cardiovascular diseases is a life-threatening complication, the development of which can be contributed by both environmental and genetic factors, the understanding of which is necessary to determine the tactics of treatment and predict the disease course. The article presents a brief review of studies on genetic predictors of CVA, in particular the association of the ABCA1 rs2230806 polymorphism and the risk of CVA in cardiovascular patients. Targeted studies of associations of the ABCA1 rs2230806 polymorphism with cerebrovascular diseases in the Russian Federation, except for studies at our university, could not be found

    Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillation

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    Atrial fibrillation (AF) is one of the most common tachyarrhythmias, contributing to both environmental and genetic factors, a clear understanding of which can be extremely important for determining management tactics and predicting the disease course. The article provides a brief overview of studies on genetic predictors of AF, in particular, SNP markers found on chromosome 10. Establishing a relationship between the identified SNPs on chromosome 10 and functional genes, changes in the structure or regulation of which can affect the development of AF, opens the veil of understanding how these SNPs affect the pathogenesis of AF
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