4 research outputs found
Antimicrobial activity of ketoconazole and fluconazole against metronidazole resistance strains of Helicobacter pylori
Resistance to drug such as metronidazole is one the commonest causes of treatment failure while eradicating Helicobacter pylori. Considering the safety of ketoconazole and fluconazole and their inhibitory activity on biosynthesis of fatty acids from cholesterol in cell membrane of H.pylori, the idea of their efficacy against H.pylori is raising. The aim of this study is to evaluate susceptibilities of metronidazole-resistant strains of H.pylori against two antifungal drugs, ketoconazole and fluconazole. In this prospective crosssectional study, 35 isolates of H.pylori from patients with digestive disorders were recruited. Plates were incubated microaerobically. Resistance to metronidazole, minimum inhibitory concentrations (MIC) of ketoconazole and fluconazole for H.pylori isolates were determined by two methods: disc diffusion and agar dilution. Disc diffusion method indicated that metronidazole resistance was seen in 11 strains out of 35. Ketoconazole and fluconazole MICs were 8 and 40mg/lit, respectively, which was confirmed by agar dilution method. Ketoconazole and fluconazole showed an excellent in vitro activity against the H.pylori isolates. However, in vivo activity of these drugs should be evaluated in controlled clinical trials. Copyright © 2006 by Razi Institute for Drug Research (RIDR)
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A DISTRIBUTED, LOW-POWER TELEMETRY SYSTEM FOR SOLAR RACE CAR APPLICATIONS
International Telemetering Conference Proceedings / October 23-26, 2000 / Town & Country Hotel and Conference Center, San Diego, CaliforniaThis student paper was produced as part of the team design competition in the University of Arizona course ECE 485, Radiowaves and Telemetry. It describes the design of a telemetry system for the University of Arizona’s Daedalus solar car. This is a distributed, low-power, telemetry-on-demand system that solves many of the problems typically encountered in this specialized telemetry application. The topology of the distributed microcontroller system is shown, as are optimal command and data packet structures. Also featured is a high-gain, low profile antenna system designed specifically for the solar car. Additionally, a customized chase car operator interface is illustrated.International Foundation for TelemeteringProceedings from the International Telemetering Conference are made available by the International Foundation for Telemetering and the University of Arizona Libraries. Visit http://www.telemetry.org/index.php/contact-us if you have questions about items in this collection