An Evaluation of the New York State Workers’ Compensation Pilot Program for Alternative Dispute Resolution

In 1995, the State 0f New York enacted legislation authorizing the establishment of a workers\u27 compensation alternative dispute resolution pilot program for the unionized sector of the construction industry. Collective bargaining agreements could establish an alternative dispute resolution process for resolving claims (including but not limited to mediation and arbitration), use of an agreed managed care organization or list of authorized providers for medical treatment that constitutes the exclusive source of all medical and related treatment, supplemental benefits, return-to-work programs, and vocational rehabilitation programs. The legislation also directed the School ofIndustrial and Labor Relations at Cornell University (ILR) to evaluate compliance with state and federal due process requirements provided in the collective bargaining agreements authorized by this act, and the use, costs and merits of the alternative dispute resolution system established pursuant to this act. In response to this legislative mandate, ILR reviewed the research previously conducted on alternative dispute resolution (ADR), generally, and in workers\u27 compensation. This included examining the purported advantages and disadvantages of ADR, the prevalence of ADR, and published statistical or anecdotal evidence regarding the impact of ADR. ILR created a research design for claimant-level and project-level analyses, and developed data collection instruments for these analyses that included an injured worker survey for ADR claimants and claimants in the traditional (statutory)workers\u27 compensation system, an Ombudsman\u27s log, a manual of data elements pertaining to ADR and comparison group claimants, and interview questions for ADR signatories and other officials. The findings in this report draw upon a comparison of claimant-level, descriptive statistics (averages) for injured workers in the ADR and traditional (statutory) workers\u27 compensation system; the results of more sophisticated, statistical analyses of claimant-level data; and project-level information (including, but not limited to, interviews with ADR signatories and dispute resolution officials)

Correlating the Energetics and Atomic Motions of the Metal-Insulator Transition of M1 Vanadium Dioxide

Materials that undergo reversible metal-insulator transitions are obvious candidates for new generations of devices. For such potential to be realised, the underlying microscopic mechanisms of such transitions must be fully determined. In this work we probe the correlation between the energy landscape and electronic structure of the metal-insulator transition of vanadium dioxide and the atomic motions occurring using first principles calculations and high resolution X-ray diffraction. Calculations find an energy barrier between the high and low temperature phases corresponding to contraction followed by expansion of the distances between vanadium atoms on neighbouring sub-lattices. X-ray diffraction reveals anisotropic strain broadening in the low temperature structure's crystal planes, however only for those with spacings affected by this compression/expansion. GW calculations reveal that traversing this barrier destabilises the bonding/anti-bonding splitting of the low temperature phase. This precise atomic description of the origin of the energy barrier separating the two structures will facilitate more precise control over the transition characteristics for new applications and devices.Comment: 11 Pages, 8 Figure

Site amplification estimates in the Garigliano valley, central Italy, based on dense array measurements of ambient noise

A frequency-domain formulation of the Aki (1957, 1965) autocorrelation method has been applied to seismic noise recorded by a 100-m wide circular array deployed on soft Holocene sediments in the Garigliano river valley, where a large amplification of ground motion during earthquakes was experienced (Rovelli et al., 1988). The application of this method to ambient noise recordings demonstrates that microtremors in the valley are dispersive and dominated by surface waves. By assuming that the vertical component reflects Rayleigh wave motion, we obtain a dispersion curve that is interpreted in terms of a layered shear-wave velocity structure. Layer thicknesses are constrained by the stratigraphic information provided by a deep hole drilled in the area, and shear velocities are estimated by means of a trial-and-error approach to achieve a satisfactory fit of the ambient noise dispersion. The best-fit velocity model is used to compute a theoretical transfer function, which is then compared with an average spectral ratio obtained from earthquake weak ground motions recorded at two stations, one in the valley and the other on a limestone reference site. An overall agreement is found between the theoretical curve and the observed spectral ratios. The discrepancies that do exist may be ascribed to the assumption of 1-D inhomogeneity which considerably simplifies the theoretical transfer function. Our results show that the spatial-correlation method can be useful to infer velocity structure down to depths of hundreds of meters, when generalized geological informations are available, and can thus provide useful constraints for theoretical methodologies for the prediction of site response

Wordom update 2: A user-friendly program for the analysis of molecular structures and conformational ensembles

We present the second update of Wordom, a user-friendly and efficient program for manipulation and analysis of conformational ensembles from molecular simulations. The actual update expands some of the existing modules and adds 21 new modules to the update 1 published in 2011. The new adds can be divided into three sets that: 1) analyze atomic fluctuations and structural communication; 2) explore ion-channel conformational dynamics and ionic translocation; and 3) compute geometrical indices of structural deformation. Set 1 serves to compute correlations of motions, find geometrically stable domains, identify a dynamically invariant core, find changes in domain-domain separation and mutual orientation, perform wavelet analysis of large-scale simulations, process the output of principal component analysis of atomic fluctuations, perform functional mode analysis, infer regions of mechanical rigidity, analyze overall fluctuations, and perform the perturbation response scanning. Set 2 includes modules specific for ion channels, which serve to monitor the pore radius as well as water or ion fluxes, and measure functional collective motions like receptor twisting or tilting angles. Finally, set 3 includes tools to monitor structural deformations by computing angles, perimeter, area, volume, β-sheet curvature, radial distribution function, and center of mass. The ring perception module is also included, helpful to monitor supramolecular self-assemblies. This update places Wordom among the most suitable, complete, user-friendly, and efficient software for the analysis of biomolecular simulations. The source code of Wordom and the relative documentation are available under the GNU general public license at http://wordom.sf.net

New insights on the interaction between thiophene derivatives and Au surfaces: the case of 3,4-ethylenedioxythiophene and the relevant polymer.

The nature of the interface between electrogenerated poly(3,4-ethylenedioxythiophene) and the Au substrate is studied in detail. In particular, the adsorption of the relevant monomer, namely, 3,4-ethylenedioxythiophene, is investigated and compared with that of other thiophene derivatives. Different deposition procedures have been adopted: very thin films of the thiophene derivatives have been obtained through chemisorption processes from vapor and liquid phases, on Au polycrystalline substrates, Au nano particles possessing different size, and a Au(111) single crystal. Different techniques, operating both in situ and ex situ, have been employed for the characterization of these deposits, that is, X-ray photoemission and surface enhanced Raman spectroscopy. The results show that the poly(3,4-ethylenedioxythiophene)/metal interface is far from being simply constituted by unreacted molecules in contact with the substrate; rather, the formation of oligothiophene species and sulfur atoms at the interface has been ascertained

Electrochemical preparation and characterisation of bilayer films composed by Prussian Blue and conducting polymer

Preparation and electrochemical behaviour of bilayer films consisting of iron(Ill) hexacyanoferrate, well known as Prussian Blue, and of poly[4,4´-bis(butylsulphanyl)-2,2´-bithiophene], on a platinum electrode, are reported. The electrochemical features of the Prussian Blue/conducting polymer bilayer system are examined in aqueous and acetonitrile solutions. Cyclic voltammetric studies show that, in acetonitrile solvent, the inner layer Prussian Blue is electroactive to some extent, though the electrochemical response of the system is mainly accounted for by poly[4,4´-bis(butylsulphanyl)-2,2´-bithiophene] outer layer. On the other hand, in aqueous solution Prussian Blue exhibits good electroactivity. Under specific experimental conditions, the individual redox behaviour of each constituent of the bilayer is evidenced in the two solvents separately, i.e., that of PB and that of poly[4,4´-bis(butylsulphanyl)-2,2´bithiophene] in aqueous and in organic solvent, respectively. However, interesting reciprocal influences are evident in the current/potential curves recorded under conditions which are discussed

Surface ruptures on cross-faults in the 24 November 1987 Superstition Hills, California, earthquake sequence

Left-lateral slip occurred on individual surface breaks along northeast-trending faults associated with the 24 November 1987 earthquake sequence in the Superstition Hills, Imperial Valley, California. This sequence included the M_s = 6.2 event on a left-lateral, northeast-trending “cross-fault” between the Superstition Hills fault (SHF) and Brawley seismic zone, which was spatially associated with the left-lateral surface breaks. Six distinct subparallel cross-faults broke at the surface, with rupture lengths ranging from about Formula to 10 km and maximum displacements ranging from 30 to 130 mm. About half a day after the M_s = 6.2 event, an M_s = 6.6 earthquake nucleated near the intersection of the cross-faults with the SHF, and rupture propagated southeast along the SHF. Whereas right-lateral slip on the SHF occurred dominantly on a single trace in a narrow zone, the cross-fault surface slip was distributed over several stands across a 10-km-wide zone. Also, whereas afterslip accounted for a large proportion of total slip on the SHF, there is no evidence for afterslip on the cross-faults. We present documentation of these surface ruptures. A simple mechanical model of faulting illustrates how the foreshock sequence may have triggered the main rupture. Displacement on other cross-faults could trigger an event on the southern San Andreas fault by a similar mechanism in the future

Hypoxia-Inducible Factor-1 as a Therapeutic Target in Endometrial Cancer Management

In the Western world, endometrial cancer (EC) is the most common malignant tumor of the female genital tract. Solid tumors like EC outgrow their vasculature resulting in hypoxia. Tumor hypoxia is important because it renders an aggressive phenotype and leads to radio- and chemo-therapy resistance. Hypoxia-inducible factor-1α (HIF-1α) plays an essential role in the adaptive cellular response to hypoxia and is associated with poor clinical outcome in EC. Therefore, HIF-1 could be an attractive therapeutic target. Selective HIF-1 inhibitors have not been identified. A number of nonselective inhibitors which target signaling pathways upstream or downstream HIF-1 are known to decrease HIF-1α protein levels. In clinical trials for the treatment of advanced and/or recurrent EC are the topoisomerase I inhibitor Topotecan, mTOR-inhibitor Rapamycin, and angiogenesis inhibitor Bevacizumab. Preliminary data shows encouraging results for these agents. Further work is needed to identify selective HIF-1 inhibitors and to translate these into clinical trials