57 research outputs found
First experimental results of very high accuracy centroiding measurements for the neat astrometric mission
NEAT is an astrometric mission proposed to ESA with the objectives of
detecting Earth-like exoplanets in the habitable zone of nearby solar-type
stars. NEAT requires the capability to measure stellar centroids at the
precision of 5e-6 pixel. Current state-of-the-art methods for centroid
estimation have reached a precision of about 2e-5 pixel at two times Nyquist
sampling, this was shown at the JPL by the VESTA experiment. A metrology system
was used to calibrate intra and inter pixel quantum efficiency variations in
order to correct pixelation errors. The European part of the NEAT consortium is
building a testbed in vacuum in order to achieve 5e-6 pixel precision for the
centroid estimation. The goal is to provide a proof of concept for the
precision requirement of the NEAT spacecraft. In this paper we present the
metrology and the pseudo stellar sources sub-systems, we present a performance
model and an error budget of the experiment and we report the present status of
the demonstration. Finally we also present our first results: the experiment
had its first light in July 2013 and a first set of data was taken in air. The
analysis of this first set of data showed that we can already measure the pixel
positions with an accuracy of about 1e-4 pixel.Comment: SPIE conference proceeding
A detector interferometric calibration experiment for high precision astrometry
Context: Exoplanet science has made staggering progress in the last two
decades, due to the relentless exploration of new detection methods and
refinement of existing ones. Yet astrometry offers a unique and untapped
potential of discovery of habitable-zone low-mass planets around all the
solar-like stars of the solar neighborhood. To fulfill this goal, astrometry
must be paired with high precision calibration of the detector.
Aims: We present a way to calibrate a detector for high accuracy astrometry.
An experimental testbed combining an astrometric simulator and an
interferometric calibration system is used to validate both the hardware needed
for the calibration and the signal processing methods. The objective is an
accuracy of 5e-6 pixel on the location of a Nyquist sampled polychromatic point
spread function.
Methods: The interferometric calibration system produced modulated Young
fringes on the detector. The Young fringes were parametrized as products of
time and space dependent functions, based on various pixel parameters. The
minimization of func- tion parameters was done iteratively, until convergence
was obtained, revealing the pixel information needed for the calibration of
astrometric measurements.
Results: The calibration system yielded the pixel positions to an accuracy
estimated at 4e-4 pixel. After including the pixel position information, an
astrometric accuracy of 6e-5 pixel was obtained, for a PSF motion over more
than five pixels. In the static mode (small jitter motion of less than 1e-3
pixel), a photon noise limited precision of 3e-5 pixel was reached
Relative entropy and the stability of shocks and contact discontinuities for systems of conservation laws with non BV perturbations
We develop a theory based on relative entropy to show the uniqueness and L^2
stability (up to a translation) of extremal entropic Rankine-Hugoniot
discontinuities for systems of conservation laws (typically 1-shocks, n-shocks,
1-contact discontinuities and n-contact discontinuities of large amplitude)
among bounded entropic weak solutions having an additional trace property. The
existence of a convex entropy is needed. No BV estimate is needed on the weak
solutions considered. The theory holds without smallness condition. The
assumptions are quite general. For instance, strict hyperbolicity is not needed
globally. For fluid mechanics, the theory handles solutions with vacuum.Comment: 29 page
Sebomic identification of sex- and ethnicity-specific variations in residual skin surface components (RSSC) for bio-monitoring or forensic applications
Background: âResidual skin surface componentsâ (RSSC) is the collective term used for the superficial layer of sebum, residue of sweat, small quantities of intercellular lipids and components of natural moisturising factor present on the skin surface. Potential applications of RSSC include use as a sampling matrix for identifying biomarkers of disease, environmental exposure monitoring, and forensics (retrospective identification of exposure to toxic chemicals). However, it is essential to first define the composition of ânormalâ RSSC. Therefore, the aim of the current study was to characterise RSSC to determine commonalities and differences in RSSC composition in relation to sex and ethnicity. Methods: Samples of RSSC were acquired from volunteers using a previously validated method and analysed by high-pressure liquid chromatographyâatmospheric pressure chemical ionisationâmass spectrometry (HPLC-APCI-MS). The resulting data underwent sebomic analysis. Results: The composition and abundance of RSSC components varied according to sex and ethnicity. The normalised abundance of free fatty acids, wax esters, diglycerides and triglycerides was significantly higher in males than females. Ethnicity-specific differences were observed in free fatty acids and a diglyceride. Conclusions: The HPLC-APCI-MS method developed in this study was successfully used to analyse the normal composition of RSSC. Compositional differences in the RSSC can be attributed to sex and ethnicity and may reflect underlying factors such as diet, hormonal levels and enzyme expression.Peer reviewedFinal Published versio
Spatially Resolved 3 um Spectroscopy of IRAS 22272+5435: Formation and Evolution of Aliphatic Hydrocarbon Dust in Proto-Planetary Nebula
We present medium-resolution 3 um spectroscopy of the carbon-rich
proto-planetary nebula IRAS 22272+5435. Spectroscopy with the Subaru Telescope
adaptive optics system revealed a spatial variation of hydrocarbon molecules
and dust surrounding the star. The ro-vibrational bands of acetylene (C2H2) and
hydrogen cyanide (HCN) at 3.0 um are evident in the central star spectra. The
molecules are concentrated in the compact region near the center. The 3.3 and
3.4 um emission of aromatic and aliphatic hydrocarbons is detected at 600--1300
AU from the central star. The separation of spatial distribution between gas
and dust suggests that the small hydrocarbon molecules are indeed the source of
solid material, and that the gas leftover from the grain formation is being
observed near the central star. The intensity of aliphatic hydrocarbon emission
relative to the aromatic hydrocarbon emission decreases with distance from the
central star. The spectral variation is well matched to that of a laboratory
analog thermally annealed with different temperatures. We suggest that either
the thermal process after the formation of a grain or the variation in the
temperature in the dust-forming region over time determines the chemical
composition of the hydrocarbon dust around the proto-planetary nebula.Comment: 14 pages, 7 figures, Accepted for publication in the Astrophyical
Journa
Exploration of scalp surface lipids reveals squalene peroxide as a potential actor in dandruff condition
Therapy and prophylaxis of opportunistic infections in HIV-infected patients: a guideline by the German and Austrian AIDS societies (DAIG/ĂAG) (AWMF 055/066)
Cluster of two cases of botulism due to Clostridium baratii type F in France, November 2014.
International audienceThe first two cases in France of botulism due to Clostridium baratii type F were identified in November 2014, in the same family. Both cases required prolonged respiratory assistance. One of the cases had extremely high toxin serum levels and remained paralysed for two weeks. Investigations strongly supported the hypothesis of a common exposure during a family meal with high level contamination of the source. However, all analyses of leftover food remained negative
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