Features of the Parameters of 24-Hours pH-Impedance and High-Resolution Esophageal Manometry in Patients with Barrett's Esophagus on Proton Pump Inhibitors

Аim: to identify predictors of insufficient effectiveness of proton pump inhibitors based on the evaluation of the results of 24-hour pH-impedance and high-resolution esophageal manometry in patients with Barrett's esophagus.Materials and methods. 52 patients with histologically confirmed Barrett's esophagus who are on therapy with proton pump inhibitors were examined. All patients underwent daily pH-impedance and high-resolution esophageal manometry.Results. According to daily pH-impedance, group 1 consisted of 37 patients who responded satisfactorily to antisecretory therapy, group 2 of 15 patients who demonstrated insufficient response to acid-suppressive therapy, 11 of whom had no clinical manifestations. The total number of reflux averaged 55 in group 1 and 106 in group 2. The average number of acid reflux in group 1 was 5.68, in group 2 — 48.5. The average number of non-acid reflux prevailed in patients of group 2 and averaged 58, in group 1 the indicator averaged 47. Evaluation of the results of high-resolution esophageal manometry showed that violations of the structure and function of the esophago-gastric junction were detected in 21 patients out of 52. Disorders of the motility of the thoracic esophagus were detected in 31 patients out of 52. When comparing the frequency of motor disorders from the thoracic esophagus in groups 1 and 2, no significant differences were obtained. However, significantly more frequent registration of violations of the structure and/or function of the esophago-gastric junction was found in the group with unsatisfactory effectiveness of proton pump inhibitors.Conclusion. In a number of patients with Barrett's esophagus, there is an insufficient effect of acid-suppressive therapy and at the same time an asymptomatic course of the disease, which may increase the risk of its progression. Predictors of insufficiently successful treatment of patients with Barrett's esophagus may be both insufficient pharmacological effect of proton pump inhibitors themselves, and motility disorders that cause the presence of non-acid reflux, decreased esophageal clearance, which in turn may cause the patient's symptoms to persist and adversely affect the condition of the esophageal mucosa

Professional thinking formation features of prospective natural science teachers relying on the competence-based approach

© 2015, Review of European Studies. All right reserved. This paper experimentally proved and implemented a specific approach to designing a control system for formation and development of professionally oriented thinking of students-future teachers of physics, chemistry and biology. Specific methods for regulating the control and self-control of the progress of its development have been proposed, developed in the logic of the educational process in a pedagogical higher school and directed to achievement of educational goals. The primary means of forming professionally oriented thinking in the unity of its procedural, substantive and operational components is to optimize the educational process of higher school through the implementation of the objectives arising from the peculiarities of professional thinking of a teacher. The contents of this article are of value to teachers of physics, chemistry and biology, as well as to future teachers

Professional thinking formation features of prospective natural science teachers relying on the competence-based approach

© 2015, Review of European Studies. All right reserved. This paper experimentally proved and implemented a specific approach to designing a control system for formation and development of professionally oriented thinking of students-future teachers of physics, chemistry and biology. Specific methods for regulating the control and self-control of the progress of its development have been proposed, developed in the logic of the educational process in a pedagogical higher school and directed to achievement of educational goals. The primary means of forming professionally oriented thinking in the unity of its procedural, substantive and operational components is to optimize the educational process of higher school through the implementation of the objectives arising from the peculiarities of professional thinking of a teacher. The contents of this article are of value to teachers of physics, chemistry and biology, as well as to future teachers

Monts du Mandara, femme Kindi / Philippe Joudiou

© 2015, Review of European Studies. All right reserved. This paper experimentally proved and implemented a specific approach to designing a control system for formation and development of professionally oriented thinking of students-future teachers of physics, chemistry and biology. Specific methods for regulating the control and self-control of the progress of its development have been proposed, developed in the logic of the educational process in a pedagogical higher school and directed to achievement of educational goals. The primary means of forming professionally oriented thinking in the unity of its procedural, substantive and operational components is to optimize the educational process of higher school through the implementation of the objectives arising from the peculiarities of professional thinking of a teacher. The contents of this article are of value to teachers of physics, chemistry and biology, as well as to future teachers

Factors in consumer choice of Russian retail chains’ private labels: The role of green attributes

The issues of green marketing, its impact on consumer behaviour, and the evolution of retail chains’ private labels (PLs) are well-covered in scientific literature. However, there is a lack of comprehensive research addressing the interconnection of these three aspects. The paper explores the factors affecting consumer decisions to purchase green private labels and identifies what product attributes Russian consumers associate with being green, i.e., safe for both the consumer and the environment at all stages of production, sales and disposal. The methodological basis of the study resides in relationship marketing theory, consumer choice theory, value perception theory and the concept of sustainable development. The data for the empirical study were obtained from in-depth expert interviews with retail chains’ representatives and respondents’ survey. The data were processed using correlation and regression analysis, as well as content analysis. The research results indicate that the price of private labels is not the sole factor in consumer choice: it is influenced by both socio-demographic characteristics of respondents and additional properties of PLs, including a set of green attributes, informative packaging, social orientation of private labels, etc. The findings of the study are valuable for planning marketing campaigns to promote PLs of retail chains