431 research outputs found
Food prosumption technologies : A symbiotic lens for a degrowth transition
Prosumption is gaining momentum among the critical accounts of sustainable consumption that have thus far enriched the marketing discourse. Attention to prosumption is increasing whilst the degrowth movement is emerging to tackle the contradictions inherent in growth-driven, technology-fueled, and capitalist modes of sustainable production and consumption. In response to dominant critical voices that portray technology as counter to degrowth living, we propose an alternative symbiotic lens with which to reconsider the relations between technology, prosumption, and degrowth living, and assess how a degrowth transition in the context of food can be carried out at the intersection of human–nature–technology. We contribute to the critical debates on prosumption in marketing by analyzing the potentials and limits of technology-enabled food prosumption for a degrowth transition through the degrowth principles of conviviality and appropriateness. Finally, we consider the sociopolitical challenges involved in mobilizing such technologies to achieve symbiosis and propose a future research agenda.©2023 Sage Publications. The article is protected by copyright and reuse is restricted to non-commercial and no derivative uses. Users may also download and save a local copy of an article accessed in an institutional repository for the user's personal reference.fi=vertaisarvioitu|en=peerReviewed
Solid-state laser system for laser cooling of Sodium
We demonstrate a frequency-stabilized, all-solid laser source at 589 nm with
up to 800 mW output power. The laser relies on sum-frequency generation from
two laser sources at 1064 nm and 1319 nm through a PPKTP crystal in a
doubly-resonant cavity. We obtain conversion efficiency as high as 2 W/W^2
after optimization of the cavity parameters. The output wavelength is tunable
over 60 GHz, which is sufficient to lock on the Sodium D2 line. The robustness,
beam quality, spectral narrowness and tunability of our source make it an
alternative to dye lasers for atomic physics experiments with Sodium atoms
Fractura triplana epifisaria distal de tibia: a propĂłsito de un caso con interposiciĂłn de periostio
Se presenta un caso de fractura triplana en 2 fragmentos en un paciente varĂłn
de 13 años tratado quirúrgicamente, observando la interposición perióstica en el plano axial a
nivel del fragmento antero-externo, que impedĂa la reducciĂłn anatĂłmica de la zona epifisaria
articular. Se analiza la anatomĂa quirĂşrgica de las fracturas triplanas considerando que esta lesiĂłn
puede ser más frecuente de lo que se ha informado, y sólo valorada en los casos en que se
emplee un abordaje antero-externo.The case of a 13-year-old boy with a two-fragment triplane fracture of the distal
epiphysis of the tibia is presented. At surgery, an interposition of the periosteum in the axial
plane behind the antero-lateral fragment, preventing the anatomical reduction of the epiphyseal
joint surface was found. The surgical anatomy of triplane fractures is review taking into account
that this lesion can be more frequent that it has been reported. The true incidence
should be evaluated at surgery by antero-lateral approach
Economic efficiency of public secondary education expenditure: how different are developed and developing countries?
Este estudio mide la eficiencia del gasto pĂşblico en educaciĂłn secundaria en 35 paĂses desarrollados y en desarrollo mediante el uso de una metodologĂa semiparamĂ©trica DEA (análisis envolvente de datos) en dos pasos. En primer lugar, implementamos dos modelos de frontera transfronteriza para el perĂodo 2009-2012: uno que utiliza un aporte fĂsico (es decir, relaciĂłn maestro-alumno) y otro que utiliza un aporte monetario (es decir, gasto gubernamental por estudiante secundario). Estos resultados se corrigen por los efectos del PIB per cápita y el logro educativo de los adultos como insumos no discrecionales. Obtenemos cuatro resultados importantes: (i) los paĂses desarrollados y en desarrollo tienen los mismos procesos de producciĂłn educativa cuando se comparan utilizando insumos fĂsicos, pero no cuando se los compara con insumos monetarios; (ii) los paĂses en desarrollo podrĂan aumentar sus tasas de matrĂcula y puntajes PISA en aproximadamente un 9% y un 5%, respectivamente, al mantener las mismas proporciones maestro-alumno y los niveles de gasto pĂşblico que los paĂses desarrollados; (iii) Irlanda, JapĂłn y Corea son paĂses eficientes en los dos modelos de frontera (Colombia tambiĂ©n se incluye en esta categorĂa cuando se utiliza la relaciĂłn maestro-alumno como insumo); y (iv) la sĂłlida evidencia empĂrica indica que tanto el ingreso como el logro educativo de los padres afectan positivamente la eficiencia de la educaciĂłn pĂşblica en ambos modelos.This study measures the efficiency of public secondary education expenditure in 35 developing and developed countries using a two-step semi-parametric DEA (data envelopment analysis) methodology. First, we implement two cross-country frontier models for the 2009-2012 period: one using a physical input (i.e., teacher-pupil ratio) and one using a monetary input (i.e., government expenditure per secondary student). These results are corrected by the effects of GDP per capita and adult educational attainment as non-discretionary inputs. We obtain four important results: (i) developed and developing countries have the same education production processes when they are compared using physical inputs but not when compared using monetary inputs; (ii) developing countries could increase their enrollment rates and PISA scores by approximately 9% and 5%, respectively, by maintaining the same teacher-pupil ratios and public spending levels as developed countries; (iii) Ireland, Japan and Korea are efficient countries in the two frontier models (Colombia is also included in this category when the teacher-pupil ratio is used as input); and (iv) robust empirical evidence indicates that both income and parental educational attainment positively affect the efficiency of public education in both models
Fracturas del macizo trocantéreo. Estudio comparativo Ender-DHS: revision de 114 casos
Se presenta un estudio retrospectivo de 114 fracturas pertrocantéreas tratadas
con enclavado elástico de Ender (71) y tornillo placa deslizante, DHS (43). Se efectuó un estudio
estadĂstico descriptivo-comparativo entre los 2 grupos de pacientes segĂşn la tĂ©cnica quirĂşrgica
empleada. Se constatĂł un mayor Ăndice de estabilidad usando el DHS (81%), frente al
6 1 % del otro grupo. La tasa de complicaciones fue del 16% y 55% respectivamente. Los resultados
clĂnicos fueron mejores en los enfermos tratados con DHS, fundamentalmente en
cuanto a la deambulaciĂłn que se consiguiĂł en el 98% (Ender 75%), ausencia de dolor y movilidad
conservada. Los autores piensan que la estabilidad preoperatoria no influye en la solidez
del montaje usando el DHS, pero con la técnica de Ender ésta disminuye en las fracturas inestables;
por ello, la tĂ©cnica de Ender estarĂa solamente indicada en el tratamiento de fracturas
estables en pacientes de edad avanzada o con mal estado general, aunque en clara competencia
con el DHS.A retrospective study of 114 intertrochanteric fractures operated on either with
Ender's rods (71) or dynamic hip screws, DHS (43) is presented. A statistical descriptive-comparative
study between the 2 groups was attempted. There was a greater index of stability using the
DHS (82%) than Ender's rods (61%). The rate of complications was 16% and 55% respectively.
The clinical outcome was better in cases treated with DHS, specially for walking ability,
which was regained in the 98% of cases (Ender 75%), painless and preserved mobility. The authors
think that the stability before operation do not influence the solidity of the assembly using
the DHS device. On the contrary, with the Ender's technique the fixation is no satisfactory in
unstables fractures. Ender's rods would only be suitable for treatment of stable fractures in older
patient or with serious associated diseases, although in clear competition with the DHS
Seismic risk in the city of Al Hoceima (north of Morocco) using the vulnerability index method, applied in Risk-UE project
The final publication is available at Springer via http://dx.doi.org/10.1007/s11069-016-2566-8Al Hoceima is one of the most seismic active regions in north of Morocco. It is demonstrated by the large seismic episodes reported in seismic catalogs and research studies. However, seismic risk is relatively high due to vulnerable buildings that are either old or don’t respect seismic standards. Our aim is to present a study about seismic risk and seismic scenarios for the city of Al Hoceima. The seismic vulnerability of the existing residential buildings was evaluated using the vulnerability index method (Risk-UE). It was chosen to be adapted and applied to the Moroccan constructions for its practicality and simple methodology. A visual inspection of 1102 buildings was carried out to assess the vulnerability factors. As for seismic hazard, it was evaluated in terms of macroseismic intensity for two scenarios (a deterministic and probabilistic scenario). The maps of seismic risk are represented by direct damage on buildings, damage to population and economic cost. According to the results, the main vulnerability index of the city is equal to 0.49 and the seismic risk is estimated as Slight (main damage grade equal to 0.9 for the deterministic scenario and 0.7 for the probabilistic scenario). However, Moderate to heavy damage is expected in areas located in the newer extensions, in both the east and west of the city. Important economic losses and damage to the population are expected in these areas as well. The maps elaborated can be a potential guide to the decision making in the field of seismic risk prevention and mitigation strategies in Al Hoceima.Peer ReviewedPostprint (author's final draft
The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death.
The linear ubiquitin chain assembly complex (LUBAC) is the only known E3 ubiquitin ligase which catalyses the generation of linear ubiquitin linkages de novo LUBAC is a crucial component of various immune receptor signalling pathways. Here, we show that LUBAC forms part of the TRAIL-R-associated complex I as well as of the cytoplasmic TRAIL-induced complex II In both of these complexes, HOIP limits caspase-8 activity and, consequently, apoptosis whilst being itself cleaved in a caspase-8-dependent manner. Yet, by limiting the formation of a RIPK1/RIPK3/MLKL-containing complex, LUBAC also restricts TRAIL-induced necroptosis. We identify RIPK1 and caspase-8 as linearly ubiquitinated targets of LUBAC following TRAIL stimulation. Contrary to its role in preventing TRAIL-induced RIPK1-independent apoptosis, HOIP presence, but not its activity, is required for preventing necroptosis. By promoting recruitment of the IKK complex to complex I, LUBAC also promotes TRAIL-induced activation of NF-κB and, consequently, the production of cytokines, downstream of FADD, caspase-8 and cIAP1/2. Hence, LUBAC controls the TRAIL signalling outcome from complex I and II, two platforms which both trigger cell death and gene activation
LRP-1-mediated intracellular antibody delivery to the Central Nervous System
The blood-brain barrier (BBB) is by far the most important target in developing new approaches to improve delivery of drugs and diagnostic tools into the Central Nervous System (CNS). Here we report the engineering of pH-sensitive polymersomes (synthetic vesicles formed by amphiphilic copolymers) that exploit endogenous transport mechanisms to traverse the BBB, enabling delivery of large macromolecules into both the CNS parenchyma and CNS cells. We achieve this by targeting the Low Density Lipoprotein Receptor-Related Protein 1 (LRP-1) receptor. We show that LRP-1 is associated with endothelial transcytosis that does not involve acidification of cargo in membrane-trafficking organelles. By contrast, this receptor is also associated with traditional endocytosis in CNS cells, thus aiding the delivery of relevant cargo within their cytosol. We prove this using IgG as a model cargo, thus demonstrating that the combination of appropriate targeting combined with pH-sensitive polymersomes enables the efficient delivery of macromolecules into CNS cells.</p
An all-solid-state laser source at 671 nm for cold atom experiments with lithium
We present an all solid-state narrow line-width laser source emitting
output power at delivered in a
diffraction-limited beam. The \linebreak source is based on a
fre-quency-doubled diode-end-linebreak pumped ring laser operating on the
transition in Nd:YVO. By using
periodically-poled po-tassium titanyl phosphate (ppKTP) in an external build-up
cavity, doubling efficiencies of up to 86% are obtained. Tunability of the
source over is accomplished. We demonstrate the suitability of
this robust frequency-stabilized light source for laser cooling of lithium
atoms. Finally a simplified design based on intra-cavity doubling is described
and first results are presented
The Mars Microphone onboard SuperCam
The Mars Microphone is one of the five measurement techniques of SuperCam, an
improved version of the ChemCam instrument that has been functioning aboard the
Curiosity rover for several years. SuperCam is located on the Rover's Mast
Unit, to take advantage of the unique pointing capabilities of the rover's
head. In addition to being the first instrument to record sounds on Mars, the
SuperCam Microphone can address several original scientific objectives: the
study of sound associated with laser impacts on Martian rocks to better
understand their mechanical properties, the improvement of our knowledge of
atmospheric phenomena at the surface of Mars: atmospheric turbulence,
convective vortices, dust lifting processes and wind interactions with the
rover itself. The microphone will also help our understanding of the sound
signature of the different movements of the rover: operations of the robotic
arm and the mast, driving on the rough floor of Mars, monitoring of the pumps,
etc ... The SuperCam Microphone was delivered to the SuperCam team in early
2019 and integrated at the Jet Propulsion Laboratory (JPL, Pasadena, CA) with
the complete SuperCam instrument. The Mars 2020 Mission launched in July 2020
and landed on Mars on February 18th 2021. The mission operations are expected
to last until at least August 2023. The microphone is operating perfectly.Comment: 40 page
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