3,581 research outputs found
The use of social networking technologies within a tertiary education environment
Social networking is continuing to increase its popularity and is impacting all aspects of modern society. One issue is how
can these social networking technologies relate to tertiary education and whether they be used effectively in this
educational context. This paper is based on prior research which was conducted at an Australian University into the design
of online teaching and learning systems from a student's perspective and uses these outcomes to focus and trial the use of two social networking technologies in a tertiary education institution
Acylation and alkylation reactions of biphenyl- and n-phenylpyrrole-alkanoic acid derivatives
Guidelines for Economic Evaluation of Public Sector Water Resource Projects
Water development plays an important role in the economy of states and regions. However, procedures for estimating the expected net worth of proposed projects have never been simple, and results have rarely been without controversy. This report presents some guidelines for the application of economic evaluation procedures in project analysis of public sector water development in North Dakota. A brief history of North Dakota water development and two case studies of North Dakota water projects are included in this report.Resource /Energy Economics and Policy,
Optical Observations of the Binary Millisecond Pulsars J2145-0750 and J0034-0534
We report on optical observations of the low-mass binary millisecond pulsar
systems J0034-0534 and J2145-0750. A faint (I=23.5) object was found to be
coincident with the timing position of PSR J2145-0750. While a galaxy or
distant main-sequence star cannot be ruled out, its magnitude is consistent
with an ancient white dwarf, as expected from evolutionary models. For PSR
J0034-0534 no objects were detected to a limiting magnitude of R=25.0,
suggesting that the white dwarf in this system is cold. Using white dwarf
cooling models, the limit on the magnitude of the PSR J0034-0534 companion
suggests that at birth the pulsar in this system may have rotated with a period
as short as 0.6 ms. These observations provide further evidence that the
magnetic fields of millisecond pulsars do not decay on time scales shorter than
1 Gyr.Comment: 6 pages, uuencoded, gz -9 compressed postscript, accepted by ApJ
The Role of Chromatin Modifications in the Evolution of Giant Plant Genomes.
Angiosperm genome sizes (GS) range ~2400-fold and comprise genes and their regulatory regions, repeats, semi-degraded repeats, and 'dark matter'. The latter represents repeats so degraded that they can no longer be recognised as repetitive. In exploring whether the histone modifications associated with chromatin packaging of these contrasting genomic components are conserved across the diversity of GS in angiosperms, we compared immunocytochemistry data for two species whose GS differ ~286-fold. We compared published data for Arabidopsis thaliana with a small genome (GS = 157 Mbp/1C) with newly generated data from Fritillaria imperialis, which has a giant genome (GS = 45,000 Mbp/1C). We compared the distributions of the following histone marks: H3K4me1, H3K4me2, H3K9me1, H3K9me2, H3K9me3, H3K27me1, H3K27me2, and H3K27me3. Assuming these histone marks are associated with the same genomic features across all species, irrespective of GS, our comparative analysis enables us to suggest that while H3K4me1 and H3K4me2 methylation identifies genic DNA, H3K9me3 and H3K27me3 marks are associated with 'dark matter', H3K9me1 and H3K27me1 mark highly homogeneous repeats, and H3K9me2 and H3K27me2 mark semi-degraded repeats. The results have implications for our understanding of epigenetic profiles, chromatin packaging and the divergence of genomes, and highlight contrasting organizations of the chromatin within the nucleus depending on GS itself
Researching creatively with pupils in Assessment for Learning (AfL) classrooms on experiences of participation and consultation
This paper reports on an ESRC TLRP project, Consulting Pupils on the Assessment of their Learning (CPAL). The CPAL project provides an additional theoretical perspective to the âeducational benefitsâ perspective of engaging pupil voice in learning and teaching (Rudduck et al., 2003) through its exploration of pupil rights specifically in relation to assessment issues presently on the policy agenda in the Northern Ireland context â notably Assessment for Learning (AfL). An emergent framework for assessing pupil rights, based on Article 12 of the United Nations Convention on the Rights of the Child (Lundy, 2007), is being used to explore the ways in which AfL classroom practice creates the conditions for increased pupil participation and consultation. Pupil views on their AfL classroom experiences and participation are explored by means of a variety of pupil-centred, creative research methods that engage and stimulate pupils to observe, communicate and analyse their learning and assessment experiences and give meaning to them. This presentation highlights preliminary data based on a sample of 11-14 years pupils' experiences of participation and consultation in classrooms adopting AfL pedagogical principles, and identifies characteristics that support or inhibit pupil participation in their learning and the expression of their views about such matters
Astonishing 35S rDNA diversity in the gymnosperm species Cycas revoluta Thunb
17 p., tablas, grĂĄficos.In all eukaryotes, the highly repeated 35S ribosomal DNA (rDNA) sequences encoding 18S-5.8S-26S ribosomal RNA (rRNA) typically show high levels of intragenomic uniformity due to homogenisation processes, leading to concerted evolution of 35S rDNA repeats. Here, we compared 35S rDNA divergence in several seed plants using next generation sequencing and a range of molecular and cytogenetic approaches. Most species showed similar 35S rDNA homogeneity indicating concerted evolution. However, Cycas revoluta exhibits an extraordinary diversity of rDNA repeats (nucleotide sequence divergence of different copies averaging 12 %), influencing both the coding and non-coding rDNA regions nearly equally. In contrast, its rRNA transcriptome was highly homogeneous suggesting that only a minority of genes (âT substitutions located in symmetrical CG and CHG contexts which were also highly methylated. Both functional genes and pseudogenes appear to cluster on chromosomes. The extraordinary high levels of 35S rDNA diversity in C. revoluta, and probably other species of cycads, indicate that the frequency of repeat homogenisation has been much lower in this lineage, compared with all other land plant lineages studied. This has led to the accumulation of methylation-driven mutations and pseudogenisation. Potentially, the reduced homology between paralogs prevented their elimination by homologous recombination, resulting in long-term retention of rDNA pseudogenes in the genome.The work was supported by the Czech Science Foundation (P501/13/10057S and P501/12/G090) and NERC (UK).Peer reviewe
Parameter Estimation from Improved Measurements of the Cosmic Microwave Background from QUaD
We evaluate the contribution of cosmic microwave background (CMB) polarization spectra to cosmological parameter constraints. We produce cosmological parameters using high-quality CMB polarization data from the ground-based QUaD experiment and demonstrate for the majority of parameters that there is significant improvement on the constraints obtained from satellite CMB polarization data. We split a multi-experiment CMB data set into temperature and polarization subsets and show that the best-fit confidence regions for the ÎCDM six-parameter cosmological model are consistent with each other, and that polarization data reduces the confidence regions on all parameters. We provide the best limits on parameters from QUaD EE/BB polarization data and we find best-fit parameters from the multi-experiment CMB data set using the optimal pivot scale of k_p = 0.013 Mpc^(â1) to be {h^2Ω_c, h^2Ω_b, H_0, A_s, n_s, Ï} = {0.113, 0.0224, 70.6, 2.29 Ă 10^(â9), 0.960, 0.086}
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