Assessment of Regional Economic Security Level in Innovative Development

Analysis of the innovative development of the regional economy is a relevant problem due to its role in ensuring the economic security of the country and achieving priority goals. The subject of the research are the regions of one of Russia's most dynamically developing macro-regions – the Volga Federal District. It features innovation clusters, a network of modern manufacturing companies, research organizations. At the same time, it developed a significant territorial heterogeneity of the regional space.Therefore, in the course of the study, a typology of the regions was drafted according to a number of indicators, which made it possible to assess the level of their innovative development and identify zones of relative stability, medium and critical state. A forecast of the main indicators of the innovation component was made showing the ability of the regions to overcome the factors preventing the development of the innovation economy.The research results showed that most of the regions have a medium level of economic security in the field of innovation. The Nizhny Novgorod Region and the Republic of Tatarstan are at a high level. The economy of these regions is characterized by a high level of diversification, resilience to instability in the domestic market and external challenges. The Saratov region, the Republic of Mari El and the Orenburg Region are in a low-level zone. A short-term forecast indicates that in general the situation will not change – the regions will increase or decrease the values of the indices within the achieved levels of economic security. A qualitative transition to a new level is possible provided that the problems that hinder the innovative economy in the regions are eliminated

A Comparative Study of the Past Tense Aspects in Russian and Italian

Introduction. The problem of aspect categorisation in Italian, as well as in other Romance languages, is studied not so profoundly compared to what has been done in Russian linguistics. The Indo-European Presence – Aorist – Perfect in their aspectual meaning, which are the most independent forms, have turned to build the tense system both in Italian and Russian. The brightest aspectual meanings are expressed in the forms of the Past. The different perception of 'completeness' and 'incompleteness' aspects in these forms by the speakers of Italian and Russian is probably connected with the peculiarities of the tense formation on the deep level of the language system. So, additional grammar comments are needed. Methodology and sources. The main language unit is believed to be the semifinitive. Thereby we can facilitate the application of formal logical modelling to the description and explanation of syntactic phenomena. The material of the investigation is the surface structure of a predicate, which is formed, on the deep level, by a verbal semifinitive and a time specifier.Results and discussion. A scheme has been elaborated, demonstrating, how a verbal semifinitive becomes polarised by a time specifier. The whole range of aspectual variants, which may occur in a predicate due to the interaction of its constituents through their charges, has been shown. It is reasoned about a charge on participle II. The notion of polarisation is added to the notions of Indefinite or Perfect aspects to represent traditional grammar tenses more exact. This investigation allows to establish a correspondence of Italian and Russian tenses to different charge states of a semifinitive, touched by a specifier. It is rather admittable that the difference between incomplete and complete aspects in Russian is expressed by participles II, which are in complex semifinitives, and in Italian – by simple semifinitives.Conclusion. A comparative analysis of the verbal aspect category in Indo-European tenses, including the past ones, can be carried out, to our mind, both by stemming from the polarisation peculiarities of verbal semifinitives, and through investigation of literature translations, where correspondence is established on the level of language examples. In this case the genetic identity of Indo-European constructions has a chance to be represented as evidently as possible

Socio-psychological features of the process of transformation of the social structure of society and the process of communication in the digital space

The article deals with such concepts as “offline environment” and “online status”. New types of migration processes in the digital space are revealed. The trends associated with stratification of society such as the transition from exclusion to inclusion and the impact of this transition to the educational space are outlined. As part of the impact of digital technologies on the social world, the changes that occur with the classical stratification criteria: income, power and profession are considered. In terms of income we are talking about such a concept as “cryptocurrency” (digital decentralized money); in terms of power the information society and the possibility of using false information to influence certain social processes, which makes the presence of formal power is not so effective, - are considered; in the part of the profession the huge mass of knowledge that is contained in the Internet and that the modern education system is not able to provide tools for navigation in this mass of knowledge, - are discussed. The main directions of changes in the cognitive and communicative aspects of communication, the negative consequences of the preference of the online environment to live communication and the impact on human mental activity, the development of addictive trends in communication by means of digital technologies, scenarios of conflict situations in the digital communication space and their impact on the social life of an individual are reviewed. Revealed the possible scenarios of the impact of the lack of non-verbal component and the critical thinking on coding and decoding of a particular information message

Functional Improvement of Non-State Pension Funds as Mechanism of Investment in Russian Economy

The article is dedicated to the search of investments in the domestic financial market that is a relevant problem for the Russian economy. The authors believe that pension funds attracted by non-state pension institutions are an essential resource for the Russian economy; practices of foreign pension institutions need to be examined and implemented to tap this resource more efficiently.The proposed measures specified in the article following the study of foreign pension funds' functioning include: changes in the criteria for balancing portfolios of Russian pension funds' securities; development of new instruments for pension funds' investment; enhancing activities of non-state pension funds' shares market; activation of pension funds' investments in shares of innovative enterprises, etc. Practical proposals on the improvement of Russian non-state pension funds' activities have been made

Experimental study of intrinsic multiple Andreev reflections effect in GdO(F)FeAs superconductor array junctions

We report the first observation of the intrinsic multiple Andreev reflections effect (IMARE) in S-n-S-...-S-arrays (S = superconductor, n = normal metal) formed by "break-junction" technique in GdO(F)FeAs superconductor (Tc = 48 - 53 K). We show that superconducting gap peculiarities at dI/dV-spectra sharpen dramatically in the arrays as compared with that in the single-contact spectra; this enables to improve significantly accuracy of the bulk superconducting parameters determination. Using IMARE, we determined the large and the small gap values \Delta_L = 11 +- 1.1 meV and \Delta_S = 2.6 +- 0.4 meV. The BCS-ratio 2\Delta_L/kTc^{local} = 5.0 - 5.9 > 3.52 (Tc^{local} is the contact area critical temperature) evidences for a strong electron-boson coupling. The results obtained agree well with our previous data by Andreev spectroscopy for single SnS-contacts.Comment: 6 pages, 6 figure

Tissue distribution of potential antidiabetic agent C7070

C7070 is a novel imidazoline receptors agonist for the treatment of diabetes mellitus. The study was included 12 male Wistar rats. The C7070 concentration was determined by highperformance liquid chromatography with tandem mass spectrometry detectio

Comparative Analysis of Clinical and Functional Results and Position of Intraocular Lens after Femtolaser-Assisted and Standard Cataract Phacoemulsification

Modern surgical treatment of cataracts provides effective results. The study of the position of the intraocular lens (IOL) in the capsule bag can be considered as one of the most important factors influencing the final visual and refractive result of the operation.Aim: comparative analysis of clinical and functional results and position of the IOL in the capsular bag, namely decentration and tilt, when performing femtolazer-assisted phacoemulsification (FLACS) and standard phacoemulsification (CPCS). Materials and methods. We surveyed 57 patients (57 eyes). FLACS was performed in 27 patients, CPCS – in 30 patients. Standard methods of research were used, determination of the position of the IOL (decentration and tilt) in the capsular bag on the device OCT-Casia2 (TOMEY, Germany) and study of wave front were conducted.Results. Comparative analysis of the obtained results showed no significant difference between groups in postoperative visual acuity, however, there was the trend towards higher performance corrected distance visual acuity and uncorrected distance in the group FLACS (0.68 ± 0.18 and 0.74 ± 0.2) compared to the group CPCS (0.58 ± 0.28 and 0.65 ± 0.24). Internal higher order aberrations were significantly low in the group with femtolazer accompaniment: in 3 mm zone almost 2 times (p = 0.041), in 5 mm zone 1.3 times (p = 0.047). Vertical decentration in a CPCS group made 0.217 ± 0.26 mm, in FLACS group – 0.118 ± 0.05 mm, the vertical tilt – 0.75 ± 0.37° and 0.54 ± 0.36 respectively. Conclusion. Decentralizations and IOL tilt tended to lower indices in the FLACS during the observation period up to 2 months after the operation, which was accompanied by lower values of higher order internal aberrations

Hypophosphatemic rickets: pathogenesis, diagnosis and treatment

Hypophosphatemic rickets (HR) - a group of diseases characterized by the development of ricketic changes in bone tissue due to increased excretion of phosphorus from the body. This form of rickets is the most common among variants of genetically determined forms of disturbances in mineral metabolism. HR is an actual medical and social problem, requiring constant updating of knowledge of both endocrinologists and doctors of other profile. This is due to the fact that the clinical picture of HR has a significant heterogeneity and can manifest as severe deformations of the skeleton, delay in physical development, severe muscle hypotension, frequent fractures, tooth abscesses, which in some cases leads to disability of the patient and, accordingly, reduces the quality of life. Timely diagnosis and adequate therapy of HR is extremely important for preventing the development of severe complications. Currently, more than 10 candidate genes are known, the defects in which lead to the development of congenital forms of GFR. Genetic diagnostics of the HR is of great importance for determining the form of the HR, and for carrying out genetic counseling of families when planning pregnancy