2,159 research outputs found

    Quantum gravity effects on Ho\v{r}ava-Lifshitz black hole

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    In this paper, we would like to obtain quantum gravity effects by using Ho\v{r}ava-Lifshitz black hole. We consider logarithmic corrected thermodynamics quantities and investigate the effects of logarithmic correction term. Logarithmic correction comes from thermal fluctuation and may be interpreted as quantum loop corrections. As black hole is a gravitational system, hence we can investigate quantum gravity effect. We find such effects on the black hole stability and obtain domain of correction coefficient.Comment: 22 pages, Accepted for publication in NP

    Demographic study of congenital talipes equinovarus deformity in central India

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    Background: Congenital idiopathic clubfoot is the most common birth defect of the musculoskeletal system affecting 1 in every 1000 live births each year. Aim of our study was to determine the demographic variables, risk factors associated with CTEV in central India.Methods: A retrospective study was conducted from January 2019 to August 2020 using data of 200 patients with CTEV registered at department of orthopaedics, Netaji Subhash Chandra Bose medical college, Jabalpur, Madhya Pradesh, India were included in our study.Results; Out of total of 200 patients, 167 patients belong to age group <1 year (83.5%) with range from 10 days -7 years. Males were twice (65%) likely affected and (53.5%) clubfoot cases had both feet affected. Right side was more affected in unilateral cases. 189 patients (94.5%) were idiopathic, whereas 11 patients (5.5%) were non-idiopathic. there were 58 (29%) children out of 200, born of consanguineous marriage of parents. Risk factors like anemia, jaundice, asphyxia, obstructed labor, history of miscarriage had positive correlation with clubfoot. CTEV patients of low birth weight <2.5 kg associated with maternal risk factors like smoking, alcohol, anemia.Conclusions: Demographic study is useful tool for determining birth prevalence and risk factors associated with CTEV. There are significantly higher proportion of consanguinity in clubfoot patients. Cultural differences may lead to differences in our findings with respect to the previous studies. These preliminary findings will help in the future for similar studies in central India as well as in the general Indian population

    A prospective study on feto-maternal outcome in patients with premature rupture of membranes at tertiary care center

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    Background: PROM is associated with increased risk of chorioamnionitis, unfavorable cervix and dysfunctional labour, increased cesarean rates, postpartum hemorrhage and endometritis in the mother. Possible neonatal outcomes in cases of PROM may include respiratory distress syndrome, hypothermia, hypoglycemia, intraventricular hemorrhage, broncho pulmonary dysplasia etc. Objective of this study the maternal and perinatal outcomes in premature rupture of membranes at term.Methods: This prospective study was done among 100 pregnant women with premature rupture of membranes after 37 completed weeks visited at department of obstetrics & Gynecology in RCSM Hospital, Kolhapur during June 2014 and June 2015. Inclusion Criteria was Gestational  age  of  >37  weeks  confirmed  by  dates,  clinical  examination  or ultrasound, cervical dilatation of <3 cms, Lack of uterine contractions for atleast 1 hour from PROM, Single live pregnancy in vertex presentation and PROM confirmed by Direct visualization or Litmus.Results: Present study found highest number of cases among age group 20-24 years and mean age was 22 years. Almost 70% cases were un-booked. Average duration to PROM to hospital admission was 9.6 hours. Most common maternal outcome was febrile illness Most common perinatal outcome was birth asphyxia and 3 perinatal death.Conclusions: Pregnancies complicated with PROM should have supervised labor preferably in an institution. Management of each case has to be individualised. A combined effort of obstetrician and neonatalogist is necessary. A good neonatal intensive care unit can be instrumental in reducing the perinatal morbidity and mortality

    Structural analysis of Salmonella enterica effector protein SopD

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    Salmonella outer protein D (SopD) is a type III secreted virulence effector protein from Salmonella enterica. Full-length SopD and SopD lacking 16 amino acids at the N-terminus (SopDDeltaN) have been expressed as fusions with GST in Escherichia coli, purified with a typical yield of 20-30 mg per litre of cell culture and crystallized. Biophysical characterization has been carried out mainly on SopDDeltaN. Analytical size exclusion chromatography shows that SopDDeltaN is monomeric and probably globular in aqueous solution. The secondary structure composition, calculated from the CD spectrum, is mixed (38% alpha-helix and 26% beta-strand). Sequence analysis indicates that SopD contains a coiled coil motif, as found in numerous other type III secretion system-associated proteins. This suggests that SopD has the potential for one or more heterotypic protein-protein interactions. Limited trypsin digestion of SopDDeltaN, monitored by both one-dimensional proton NMR spectroscopy and SDS-PAGE, shows that the protein has a large, protease-resistant core domain of 286 amino acid residues. This single-domain architecture suggests that SopD lacks a cognate chaperone. In crystallization trials, SopDDeltaN produced better crystals than either full-length SopD or trypsin-digested SopDDeltaN. Diffraction to 3.0 Angstrom resolution has so far been obtained from crystals of SopDDeltaN

    Exoplanet properties from Lick, Keck and AAT

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    Doppler-shift measurements with a remarkable precision of Δλ/λ=3×10-9, corresponding to velocities of 1 m s-1, have been made repeatedly of 2500 stars located within 300 light years. The observed gravitational perturbations of the stars have revealed 250 orbiting planets, with 27 that cross in front of the host star, blocking a fraction of the starlight to allow measurement of the planet's mass, radius and density. Two new discoveries are the first good analog of Jupiter (HD 154345b) and the first system of five planets (55 Cancri). The predominantly eccentric orbits of exoplanets probably result from planet planet gravitational interactions or angular momentum exchange by mean-motion resonances. The planet mass distribution ranges from ~15 MJUP to as low as ~5 MEarth and rises toward lower masses as dN/dM~M-1.1. The distribution with orbital distance, a, rises (in logarithmic intervals) as dN/d log a~a+0.4. Extrapolation and integration suggests that 19% of all Sun-like stars harbor a gas-giant planet within 20 AU, but there remains considerable incompleteness for large orbits. Beyond 20 AU, the occurrence of gas-giant planets may be less than a few per cent as protoplanetary disk material there has lower densities and is vulnerable to destruction. Jupiter-mass planets occur more commonly around more massive stars than low mass stars. The transit of the Neptune-mass planet, Gliese 436b, yields a density of 1.55 g cm-3 suggesting that its interior has an iron silicate core surrounded by an envelope of water ice and an outer H He shell. Planets with masses as low as five Earth-masses may be commonly composed of iron nickel, rock and water along with significant amounts of H and He, making the term 'super-Earth' misleading. The transiting planet HD147506b has high orbital eccentricity but no significant orbital inclination to the line of sight, presenting a puzzle about its history. Its orbit together with the mean motion resonances of 4 of the 22 multi-planet systems provides further evidence for the role of planet planet interactions in shaping planetary architectures

    Andreev Scattering and the Kondo Effect

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    We examine the properties of an infinite-UU Anderson impurity coupled to both normal and superconducting metals. Both the cases of a quantum dot and a quantum point contact containing an impurity are considered; for the latter, we study both one and two-channel impurities. Using a generalization of the noncrossing approximation which incorporates multiple Andreev reflection, we compute the impurity spectral function and the linear-response conductance of these devices. We find generically that the Kondo resonance develops structure at energies corresponding to the superconducting gap, and that the magnitude of the resonance at the Fermi energy is altered. This leads to observable changes in the zero-bias conductance as compared to the case with no superconductivity.Comment: 8 pages, 7 figures; expanded version to appear in PR

    Stellar contents of two intermediate age clusters: NGC 1912 and NGC 1907

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    We present CCD photometry in a wide field around two open clusters, NGC 1912 and NGC 1907. The stellar surface density profiles indicate that the radii of the clusters NGC 1912 and NGC 1907 are ~14' and ~6' and respectively. The core of the cluster NGC 1907 is found to be 1'.6۪'3, whereas the core of the cluster NGC 1912 could not be defined due to its significant variation with the limiting magnitude. The clusters are situated at distances of 1400±100 pc (NGC 1912) and 1760±100pc (NGC 1907), indicating that in spite of their close locations on the sky they may be formed in different parts of the Galaxy. Although the mass functions for the clusters are quite noisy, in the given mass range the slopes of the mass functions for clusters NGC 1912 and NGC 1907 turn out to be -1.12 ±0.30 and -1.23 ± 0.21, respectively, which are in agreement with the Salpeter value. Because the ages of the clusters are much higher than the estimated relaxation time-scales, dynamical relaxation may be one of the reasons for the observed mass segregation in the clusters. A comparison of the observed CMDs of the clusters with the synthetic CMDs gives a photometric binary content as 30± 10% (mass range 1.0 ≤M⊙ ≤3.1) and 20±10% (mass range 1.2 ≤M⊙ ≤3.2 ) in the case of NGC 1912 and NGC 1907, respectively

    Cellular Automata with Synthetic Image A Secure Image Communication with Transform Domain

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    &nbsp; &nbsp; Image encryption has attained a great attention due to the necessity to safeguard confidential images. Digital documents, site images, battlefield photographs, etc. need a secure approach for sharing in an open channel. Hardware – software co-design is a better option for exploiting unique features to cipher the confidential images. Cellular automata (CA) and synthetic image influenced transform domain approach for image encryption is proposed in this paper. The digital image is initially divided into four subsections by applying integer wavelet transform. Confusion is accomplished on low – low section of the transformed image using CA rules 90 and 150. The first level of diffusion with consecutive XORing operation of image pixels is initiated by CA rule 42. A synthetic random key image is developed by extracting true random bits generated by Cyclone V field programmable gate array 5CSEMA5F31C6. This random image plays an important role in second level of diffusion. The proposed confusion and two level diffusion assisted image encryption approach has been validated through the entropy, correlation, histogram, number of pixels change rate, unified average change intensity, contrast and encryption quality analyses

    Roles of Dopamine Receptor on Chemosensory and Mechanosensory Primary Cilia in Renal Epithelial Cells

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    Dopamine plays a number of important physiological roles. However, activation of dopamine receptor type-5 (DR5) and its effect in renal epithelial cells have not been studied. Here, we show for the first time that DR5 is localized to primary cilia of LLCPK kidney cells. Renal epithelial cilia are mechanosensory organelles that sense and respond to tubular fluid-flow in the kidney. To determine the roles of DR5 and sensory cilia, we used dopamine to non-selectively and fenoldopam to selectively activate ciliary DR5. Compared to mock treatment, dopamine treated cells significantly increases the length of cilia. Fenoldopam further increases the length of cilia compared to dopamine treated cells. The increase in cilia length also increases the sensitivity of the cells in response to fluid-shear stress. The graded responses to dopamine- and fenoldopam-induced increase in cilia length further show that sensitivity to fluid-shear stress correlates to the length of cilia. Together, our studies suggest for the first time that dopamine or fenoldopam is an exciting agent that enhances structure and function of primary cilia. We further propose that dopaminergic agents can be used in cilio-therapy to treat diseases associated with abnormal cilia structure and/or function
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