386 research outputs found
Hadroproduction of electroweak gauge boson plus jets and TMD parton density functions
If studies of electroweak gauge boson final states at the Large Hadron
Collider, for Standard Model physics and beyond, are sensitive to effects of
the initial state's transverse momentum distribution, appropriate
generalizations of QCD shower evolution are required. We propose a method to do
this based on QCD transverse momentum dependent (TMD) factorization at high
energy. The method incorporates experimental information from the
high-precision deep inelastic scattering (DIS) measurements, and includes
experimental and theoretical uncertainties on TMD parton density functions. We
illustrate the approach presenting results for production of W-boson + n jets
at the LHC, including azimuthal correlations and subleading jet distributions.Comment: 9 pages, 4 figures. v2: comments and references added, typos
corrected; results unchange
The CCFM uPDF evolution uPDFevolv
uPDFevolv is an evolution code for TMD parton densities using the CCFM
evolution equation. A description of the underlying theoretical model and
technical realization is given together with a detailed program description,
with emphasis on parameters the user may want to changeComment: Code and description on https://updfevolv.hepforge.org Version to be
published in EPJ
Forward Jets and Energy Flow in Hadronic Collisions
We observe that at the Large Hadron Collider, using forward + central
detectors, it becomes possible for the first time to carry out calorimetric
measurements of the transverse energy flow due to "minijets" accompanying
production of two jets separated by a large rapidity interval. We present
parton-shower calculations of energy flow observables in a high-energy
factorized Monte Carlo framework, designed to take into account QCD logarithmic
corrections both in the large rapidity interval and in the hard transverse
momentum. Considering events with a forward and a central jet, we examine the
energy flow in the interjet region and in the region away from the jets. We
discuss the role of these observables to analyze multiple parton collision
effects.Comment: 9 pages, 5 figures. Version2: added results on azimuthal
distributions and more discussion of energy flow definition using jet
clusterin
The CCFM Monte Carlo generator CASCADE 2.2.0
CASCADE is a full hadron level Monte Carlo event generator for ep, \gamma p
and p\bar{p} and pp processes, which uses the CCFM evolution equation for the
initial state cascade in a backward evolution approach supplemented with off -
shell matrix elements for the hard scattering. A detailed program description
is given, with emphasis on parameters the user wants to change and variables
which completely specify the generated events
5-Aminolaevulinic Acid (ALA) for the Fluorescence Detection of Bronchial Tumors
At the moment only early detection of lung cancer offers a good prognosis for the patients. Conventional white light endoscopy is mostly insufficient for early diagnosis. Therefore we
developed a system of fluorescence diagnosis using 5-aminolaevulinic acid (ALA)
exogeneously applied. As precursor of the heme synthesis it is metabolized to protoporphyrin
IX – a red fluorescent substance. Therefore protoporphyrin IX accumulates in tumorous and
premalignant tissue, and can be directly visualized by fluorescence bronchoscopy. Excitation
with blue light (380–435 nm) causes a red fluorescence, which can be detected after filtering
most of the blue component with the naked eye or a camera system. After earlier work with
laser systems and cold light sources we now use the system D-Light AF for the fluorescence
diagnosis using ALA-induced protoporphyrin IX fluorescence
Targeted natural killer cell–based adoptive immunotherapy for the treatment of patients with NSCLC after radiochemotherapy: a randomized phase II clinical trial
Purpose: Non–small cell lung cancer (NSCLC) is a fatal disease with poor prognosis. A membrane-bound form of Hsp70 (mHsp70) which is selectively expressed on high-risk tumors serves as a target for mHsp70-targeting natural killer (NK) cells. Patients with advanced mHsp70-positive NSCLC may therefore benefit from a therapeutic intervention involving mHsp70-targeting NK cells. The randomized phase II clinical trial (EudraCT2008-002130-30) explores tolerability and efficacy of ex vivo–activated NK cells in patients with NSCLC after radiochemotherapy (RCT).
Patients and Methods: Patients with unresectable, mHsp70-positive NSCLC (stage IIIa/b) received 4 cycles of autologous NK cells activated ex vivo with TKD/IL2 [interventional arm (INT)] after RCT (60–70 Gy, platinum-based chemotherapy) or RCT alone [control arm (CTRL)]. The primary objective was progression-free survival (PFS), and secondary objectives were the assessment of quality of life (QoL, QLQ-LC13), toxicity, and immunobiological responses.
Results: The NK-cell therapy after RCT was well tolerated, and no differences in QoL parameters between the two study arms were detected. Estimated 1-year probabilities for PFS were 67% [95% confidence interval (CI), 19%–90%] for the INT arm and 33% (95% CI, 5%–68%) for the CTRL arm (P = 0.36, 1-sided log-rank test). Clinical responses in the INT group were associated with an increase in the prevalence of activated NK cells in their peripheral blood
kt - factorization and CCFM - the solution for describing the hadronic final states - everywhere ?
The basic ideas of kt-factorization and CCFM parton evolution is discussed.
The unintegrated gluon densities, obtained from CCFM fits to the proton
structure function data at HERA are used to predict hadronic final state cross
sections like jet production at HERA, but also comparisons with recent
measurements of heavy quark production at the Tevatron are presented. Finally,
the kt-factorization approach is applied to Higgs production at high energy
hadron hadron colliders and the transverse momentum spectrum of Higgs
production at the LHC is calculated.Comment: to be published in MPLA, replaced with new reference
Back-to-back azimuthal correlations in Z+jet events at high transverse momentum in the TMD parton branching method at next-to-leading order
Azimuthal correlations in Z+jet production at large transverse momenta are
computed by matching Parton - Branching (PB) TMD parton distributions and
showers with NLO calculations via MCatNLO. The predictions are compared with
those for dijet production in the same kinematic range. The azimuthal
correlations between the Z boson and the leading jet are steeper
compared to those in dijet production at transverse momenta GeV
, while they become similar for very high transverse momenta
GeV. The different patterns of Z+jet and dijet azimuthal correlations can be
used to search for potential factorization - breaking effects in the
back-to-back region, which depend on the different color and spin structure of
the final states and their interferences with the initial states. In order to
investigate these effects experimentally, we propose to measure the ratio of
the distributions in for Z+jet - and multijet production at low
and at high transverse momenta, and compare the results to predictions obtained
assuming factorization. We examine the role of theoretical uncertainties by
performing variations of the factorization scale, renormalization scale and
matching scale. In particular, we present a comparative study of matching scale
uncertainties in the cases of PB -TMD and collinear parton showers
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