6 research outputs found

    Visceral leishmaniasis in 26 HIV-negative adults

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    <p>Abstract</p> <p>Background</p> <p>Visceral leishmaniasis is a notifiable parasitic disease that had increased in incidence in our region on the past few years. It is common in children. In adults, it occurs more on a background of immunodeficiency, and frequently with incomplete clinical manifestations, making the diagnosis complicated.</p> <p>Findings</p> <p>The aim of our study is to reveal different features of visceral leishmaniasis in adults, through the analysis of its epidemiological, clinical and biological parameters, in a group of 26 patients. No one was infected with HIV or under immunosuppressive therapy Clinical presentation was generally conservative, but there was few differences in adults compared to children, concerning both the clinical symptoms and the laboratory parameters. Diagnosis was provided by direct examination of bone marrow smears in 24 cases (sensitivity 92%), and anti-leishmanial serology in the others.</p> <p>Conclusion</p> <p>We should think to the diagnosis of VL even if the patient is not known immunocompromised, and even if the clinical is incomplete, to avoid a delay of care which can lead to serious complications.</p

    Small-bowel diverticulosis associated with large duodenal diverticulum complicated with cholestasis

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    Les diverticules duodĂ©naux et grĂȘliques sont rares. Ils sont souvent asymptomatiques, leur dĂ©couverte Ă©tant alors fortuite. Cependant, des complications peuvent survenir dans 5 Ă  20% des cas. Les complications les plus frĂ©quentes sont la perforation, l’hĂ©morragie digestive et l’occlusion. Par ailleurs, d’autres complications sont plus spĂ©cifiques au diverticule duodĂ©nal en position pĂ©ri-ampullaire. En effet, la compression intermittente de la voie biliaire principale ou du confluent canalaire bilio-pancrĂ©atique peut ĂȘtre Ă  l’origine d’une cholestase symptomatique ou non. Nous rapportons l’observation d’une patiente ĂągĂ©e de 70 ans, cholecystectomisĂ©e il y a 30 ans, hospitalisĂ©e pour douleurs abdominales chroniques ; le bilan retrouve une cholestase anictĂ©rique avec dilatation des voies biliaires Ă  l’échographie et Ă  la TDM abdominale sans obstacle individualisable. La bili-IRM a montrĂ© un Ă©norme diverticule duodĂ©nal pĂ©ri-ampullaire. Par ailleurs, le transit du grĂȘle a rĂ©vĂ©lĂ© une diverticulose duodĂ©no-grĂȘlique. En l’absence d’indication chirurgicale, une surveillance clinique et para-clinique simple a Ă©tĂ© prĂ©conisĂ©e
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