Russian consensus statement on the diagnosis and treatment of patients with carotid stenosis

Carotid stenosis is a multidisciplinary problem that requires the involvement of a specialists’ team, including cardiovascular surgeons, neurosurgeons, endovascular surgeons, cardiologists, neurologists, and internists. In this consensus statement, a group of experts considered the main stages of diagnosing carotid stenosis, as well as discussed, the necessary prevention methods and features of choosing the optimal treatment approach. The aim was to provide concise and structured information on the management of patients with carotid stenosis. This document was developed based on the updated clinical guidelines of the European Society for Vascular Surgery and the American Association for Vascular Surgery, taking into account the consensus opinion of Russian experts

THROMBOCYTOPENIA IN THE STRUCTURE OF HEMATOLOGICAL DISORDERS IN PATIENTS OF A MULTIPROFILE HOSPITAL AND POSSIBLE WAYS TO OPTIMIZE ITS EVALUATION

Analysis of the prevalence of thrombocytopenia in a multidisciplinary hospital, where it is treated about 25,000 patients a year, shows that from 1.15% to 1.45% of patients have threat reduction platelets less than 100x109/l. 40,2% of them (on average, 127 people per year) receive heparin and can potentially be seen as patients that are suspected to heparin-induced thrombocytopenia (HIT). Timely identification of such patients, the use of two rules – 4T and «100–5—100» allows you not to miss the patient with the development of HIT, time to switch to alternative anticoagulants and, if necessary, to stop the flushing of venous catheters with heparin solution. This tactic allows to reduce the number of patients, receiving heparin and thrombocytopenia below 100 х 109/l, almost 3 times as took place among hospitalized and patients in intensive care units in 3 years of using the mentioned tactics

Clinical and biochemical assessment of the state of oral tissue in patients with paranoid schizophrenia of continuous flow

Research objective. To assess the state of oral tissue in patients with paranoid schizophrenia of continuous flow according to biochemical indices of mixed saliva and to compare with clinical parameters. Material and methods. 57 patients with continuous paranoid schizophrenia were divided into 5 groups according to age. The rate of salivation, pH was calculated, the activity of AST, ALT, APF, LDH, total protein, IL-1β, —4, —6, —10, TNF-α was determined in saliva. All the results obtained were processed by variational statistics, correlation analysis by Spearmen. Results and discussion. Patients with paranoid schizophrenia of the continuous course revealed an unfavorable clinical status of the oral tissues, which correlates with the parameters of mixed saliva

THE SCIENTIFIC USE OF THE UKRVO JOINT DIGITAL ARCHIVE: GRBs FIELDS, PLUTO, AND SATELLITES OF OUTER PLANETS

ABSTRACT. In the framework of UkrVO national project the new methods of plate digital image processing are developed. The photographic material of the UkrVO Joint Digital Archive (JDA  –  http://gua.db.ukr-vo.org/vo-mao/DB/archivespecial.php) is used for the solution of classic astrometric problem – positional and photometric determinations of objects registered on the plates. The results of tested methods show that the positional  rms errors are better than ±150 mas for both coordinates  and photometric ones are better than ±0.20m with the Tycho-2 catalogue as reference.   In the framework of UkrVO national project the new methods of plate digital image processing are developed. The photographic material of the UkrVO Joint Digital Archive (JDA  –  http://gua.db.ukr-vo.org/vo-mao/DB/archivespecial.php) is used for the solution of classic astrometric problem – positional and photometric determinations of objects registered on the plates. The results of tested methods show that the positional  rms errors are better than ±150 mas for both coordinates  and photometric ones are better than ±0.20m with the Tycho-2 catalogue as reference.

Laboratory medicine in modern teaching clinical physicians

At the end of the last century and, especially, in the first two decades of the 21st century, a significant technological breakthrough took place in clinical laboratory diagnostics in Russia. The transition from manual techniques to high-tech and high-performance automated systems has changed the potential of laboratory medicine. The laboratory has become a high-tech, rapidly developing branch of medical organizations. Following the changes in technology, the range of diagnostic tests began to alter, while the list of laboratory tests available grew. These dynamics are growing every year. Simple routine techniques, practiced for all patients, are complemented by more specific tests. The place of conventional routine tests has been determined by many years of practical experience, while modern analyzers allow the use of tests with a high evidence value of recommendations, which, in the context of evidence-based medicine, enable the clinician to conduct a personalized diagnostic search. At the same time, in order to use all the possibilities of laboratory medicine, the discipline Clinical Laboratory Diagnostics should be included in educational programs at different stages of a doctor's training