Young children and tablets: the views of parents and teachers

Touch screen tablets are now widely available and due to the increasing use of these technologies in homes and early years centres, it is important to consider parent and teacher views about their use. This paper reports on an interview study which explored the perspectives of four parents of children aged 20–36 months and their two teachers in one early learning centre in the north of England. Key findings were that parents and teachers had a positive perspective on young children’s use of tablets and viewed them as educationally valuable. They expressed that they did not wish children to be left behind in learning about new technologies and emphasized having a ‘balanced’ approach to tablets. However, there were also concerns voiced over the potential overuse and misuse of tablets at home suggesting more guidance for parents is needed to support young children’s experiences with tablets

Digital play: a new classification

This paper draws on an ESRC-funded study of play and creativity in preschool-aged children’s use of apps in the UK. The main objectives of the study were to collect information about access to and use of apps in the home, establish the most popular apps and identify the features of those apps that are successful in promoting play and creativity. A mixed-method approach was used to collect data, including video filming of children using the most popular apps. In identifying play types that emerged in the analysis of data, the team utilised an established taxonomy, which outlines sixteen play types. This taxonomy was reviewed and adapted to analyse data from the project relating to digital play. Through this process, an additional type of play, transgressive play, was identified and added to the taxonomy. The paper outlines the implications of the revised taxonomy for future studies of play

Changes in activity of free radical processes in tissues of timorous and contralateral ovaries under the effect of neoadjuvant chemotherapy

Ovarian cancer is still among the most actual unsolved problems in oncogynecological practice. We studied the effect of neoadjuvant polychemotherapy on parameters of free radical processes in tissues of tumorous and contralateral (non-tumorous) ovaries. Morphologically healthy tissues of contralateral ovaries had signs of the imbalance in antioxidant factors similar to those in the ovaries affected by tumor. Neoadjuvant polychemotherapy resulted in normalization of metabolism parameters in both tumorous and contralateral ovaries

Neoadjuvant chemoimmunotherapy for inoperable ovarian cancer

Aim. To assess the results of neoadjuvant chemoimmunotherapy for patients with inoperable ovarian cancer. Methods. The study included 72 patients with stage IIIС-IV ovarian cancer divided into three groups: with neoadjuvant chemotherapy and with neoadjuvant chemoimmunotherapy with intramuscular and intraperitoneal interferon gamma. Direct and immediate results of the treatment were studied and compared to assess the efficacy of treatment. Besides, ploidy determination and cell cycle analysis were performed on the fresh postoperative specimens by DNA flow cytometry. Immune status was evaluated before and after neoadjuvant therapy. Results. After neoadjuvant polychemotherapy, in the group of intramuscular interferon gamma high-volume surgery was performed in 81.8% of patients, in the group of intraperitoneal interferon gamma - in 87.5% (p ≤0.05), and in the control group (without interferon gamma) high-volume surgery was performed in 34.6% of patients. Recurrence rates were found to be 25% in the group of intraperitoneal interferon gamma (