Choice of antihypertensive therapy in hypertensive patients with critical coronary artery stenosis

Sixty patients with stages II-III AH were studied. ABPM was performed in all the patients. DBPP was assessed by the degree of nocturnal BP lowering. Patients were randomized into groups receiving perindopril or losartan potassium. Perindopril was prescribed at a dose of 4 mg/day with subsequent rising up to 8 mg/day during 7 days. The initial dose of losartan potassium was 25 mg with subsequent rising up to 50 mg 2 times a day. The duration of observation was 8 weeks. Thus, perindopril therapy in hypertensive patients in the preoperative CABG period increased the number of people with normal BP profileyesБелгородский госуниверсите

Choice of antihypertensive therapy in hypertensive patients with critical coronary artery stenosis

yesSixty patients with stages II-III AH were studied. ABPM was performed in all the patients. DBPP was assessed by the degree of nocturnal BP lowering. Patients were randomized into groups receiving perindopril or losartan potassium. Perindopril was prescribed at a dose of 4 mg/day with subsequent rising up to 8 mg/day during 7 days. The initial dose of losartan potassium was 25 mg with subsequent rising up to 50 mg 2 times a day. The duration of observation was 8 weeks. Thus, perindopril therapy in hypertensive patients in the preoperative CABG period increased the number of people with normal BP profileБелгородский госуниверсите

Analysis of international practice in the development and implementation of public administration digital platforms

Implementation of the task of creating a digital platform for a full-featured system of information and analytical support for public administration at the federal, regional and municipal levels, requires a lot of resources and serious expertise.In this regard, the subject of the study was the experience and trends in the construction and operation of digital platforms for state and public administration. The aim of the paper was to summarize the international practice of creating, operating and developing digital public administration platforms. As part of the study, the authors carry out a systematic, content and comparative analysis of various sources: regulatory documents, scientific papers, analytical materials of a number of international organizations, etc.The article presents the results of a study of world experience in the application of various tools to support e-government and support digital governance platforms. The authors describe global trends in the use of information and communication technologies to support public administration. The paper presents a list of general principles for the operation of digital platforms, gives the results of the analysis on the compliance with these principles of the state digital platform of the European Union, highlights its distinctive properties.The article forms proposals and development directions, based on the results and available studies on the development and promotion of digital management platforms, that can help accelerate the spread of digital transformation of public administration in the Russian Federation. The results of the study can be applied to identify the potential of the existing platform, its strengths and weaknesses, including in the context of the possibilities of developing the process of digital transformation of governance, as well as effectively moving towards the formation of the digital platform of public administration in the Russian Federation

Cohort profile. the ESC-EORP chronic ischemic cardiovascular disease long-term (CICD LT) registry

The European Society of cardiology (ESC) EURObservational Research Programme (EORP) Chronic Ischemic Cardiovascular Disease registry Long Term (CICD) aims to study the clinical profile, treatment modalities and outcomes of patients diagnosed with CICD in a contemporary environment in order to assess whether these patients at high cardiovascular risk are treated according to ESC guidelines on prevention or on stable coronary disease and to determine mid and long term outcomes and their determinants in this population