Editorial: Towards leaner and more effective value chain development

Value chain development (VCD) is a common term in today’s development lexicon1, where its use tends to conjure passionate ideas about how development programming can support smallholder participation in growing markets in the interest of economic growth, job creation, gender empowerment, and sustainable use of natural resources, among other goals. Since the early 2000s, Enterprise Development and Microfinance (EDM) has featured considerable debate on how to design market-oriented development interventions with smallholders, often based on positive experiences by a given NGO or project in a particular context. Early articles helped to put VCD on the development agenda, while advancing innovation in market-based project design and implementation. However, after more than a decade of it being firmly placed on the agenda, we still know relatively little about VCD. Apart from isolated case studies, the question of whether VCD has lived up to the expectations of smallholders, of the private sector, and of development agencies remains an open one. This double edition of EDM addresses the design, implementation, and impact of VCD support to smallholders and to small and medium enterprises (SMEs) as an important, yet under-researched dimension of VCD. The eight articles look into the needs and opportunities for increasing the effectiveness of VCD support services, with discussions on: the role of NGOs or governments in VCD; how large-scale buyers and certification programs shape VCD; and the role of finance and impact bonds in VCD. Advancing ideas on how to get the right mix of services, at the right time, to the right people, taking into account variations in the context in which livelihoods and business activities are embedded, will help stakeholders to effectively deliver on poverty and broader development goals

Modern concepts in non-surgical esthetics; a review

New non-surgical esthetics is the most dynamic field in contemporary medicine. At the same time, it is greatly influenced by our contemporary society. This paper reviews modern methods used in non-surgical esthetics, especially in Romania. From injectology and non-surgical face lifting to non-surgical body contouring, we analyzed all procedures performed by Romanian physicians, and we show the advantages and disadvantages of the advanced esthetic procedures. Injectology typically implies hyaluronic acid, botox and mesotherapy (for wrinkles and rejuvenation). Laser and radiofrequency treatment are used for wrinkles as well, with fewer unwanted adverse reactions and results exceeding those of injectables. Non-surgical lifting has gained more ground because it requires little recovery time and the results are very positive. Elective treatment for facial discoloration is the laser approach. For non-surgical body contouring, cryolipolisis, vacuum, radio frequency, and infrared systems have all revolutionized this part of esthetics, but each has limitations, and only after establishing the correct course of action, might we think of achieving favorable results and thus raising to the expectations of patients

Dynamic Structural Flexibility of Fe-MOF-5 Evidenced by ⁵⁷Fe Mössbauer Spectroscopy

Temperature-dependent ⁵⁷Fe Mössbauer spectra were collected on Fe[subscript x]Zn[subscript 4−x](1,4-benzenedicarboxylate)₃ (Fe-MOF-5). When measured under an Ar atmosphere, the data at higher temperatures reveal thermal population of the lowest-lying electronic excited state, as expected for low symmetry tetrahedral ferrous ions. In the presence of N₂, however, the temperature dependence becomes exaggerated and the spectra cannot be fitted to a single species. A fluctuating electric field gradient at the Fe nuclei best explains these data and suggests dynamic structural distortions induced by weak interactions with N₂. This direct evidence of dynamic behaviour at MOF open metal sites is relevant for the use of MOF SBUs in catalysis, gas separation, and other applications that invoke similar phenomena

Management of Banana Xanthomonas Wilt: Evidence from impact of adoption of cultural control practices in Uganda

Banana Xanthomonas Wilt (BXW) is an important emerging and non-curable infectious plant pathogen in sub-Saharan Africa that can cause up to 100% yield loss, negatively impacting sustainable access to food and income to more than 100 million banana farmers. This study disentangles adopters into partial and full adopters to investigate the factors that are relevant to sustain the adoption process of BXW control practices and quantifies the impact of adopting the practices. Data from a randomly selected sample of 1200 banana farmers in Uganda where the disease is endemic was used. A multinomial logit model was used to determine the factors affecting adoption of control practices and augmented inverse probability weighting was employed to estimate the impacts of adoption on banana productivity and sales. Results show that training a woman farmer and having diverse sources of information about BXW control practices increased adoption of the control practices and reduced the disease incidences. Farmers who adopted all the recommended control practices achieved significantly the highest values of banana production and sales. We conclude that improving information access through farmers’ preferred communication channels, having women-inclusive trainings, and a combination of cultural practices are effective ways for sustaining adoption of the control practices

Microbiota signatures in type-2 diabetic patients with chronic kidney disease - A Pilot Study

The human microbiota is paramount for normal host physiology. Altered host-microbiome interactions are part of the pathogenesis of numerous common ailments. Currently, much emphasis is placed on the involvement of the microbiome in the pathogenesis of type-2 diabetes mellitus (T2DM), impaired glucose tolerance, and other metabolic disorders (i.e. obesity). Several studies found highly significant correlations of specific intestinal bacteria with T2DM. A better understanding of the role of the microbiome in diabetes and its complications might provide new insights in the development of new therapeutic principles. Our pilot study investigates the microbiota patterns in Romanian type-2 diabetic patients with diabetic kidney disease. Fecal samples were collected from type 2-diabetic patients and healthy controls and further used for bacterial DNA isolation. Using 16 rDNA qRT-PCR, we analyzed phyla abundance (Bacteroidetes, Firmicutes) as well as the relative abundance of specific bacterial groups (Lactobacillus sp., Enterobacteriaceae, Ruminococus sp., Prevotella sp., Faecalibacterium sp., Clostridium coccoides, Clostridium leptum). Our study also investigates the diabetic fungal microbiome for the first time. Furthermore, we report significant correlations between the treatment regimen and microbiota composition in diabetic nephropathy

Effects of deposition dynamics on epitaxial growth

The dynamic effects, such as the steering and the screening effects during deposition, on an epitaxial growth (Cu/Cu(001)), is studied by kinetic Monte Carlo simulation that incorporates molecular dynamic simulation to rigorously take the interaction of the deposited atom with the substrate atoms into account. We find three characteristic features of the surface morphology developed by grazing angle deposition: (1) enhanced surface roughness, (2) asymmetric mound, and (3) asymmetric slopes of mound sides. Regarding their dependence on both deposition angle and substrate temperature, a reasonable agreement of the simulated results with the previous experimental ones is found. The characteristic growth features by grazing angle deposition are mainly caused by the inhomogeneous deposition flux due to the steering and screening effects, where the steering effects play the major role rather than the screening effects. Newly observed in the present simulation is that the side of mound in each direction is composed of various facets instead of all being in one selected mound angle even if the slope selection is attained, and that the slope selection does not necessarily mean the facet selection.Comment: 9 pages, 10 figure