1,272 research outputs found
Factorization in graviton interactions
The study of factorization in the linearized gravity is extended to the
graviton scattering processes with a massive scalar particle, with a massless
vector boson and also with a graviton. Every transition amplitude is shown to
be completely factorized and the physical implications of their common factors
are discussed.Comment: 5 pages, Revtex 3.0, SNUTP 93-7
Phenomenological Impacts of the CP-odd Rephase-Invariant Phase of the Chargino Mass Matrix in the Production of Light Chargino-Pair in Collisions
One CP--odd rephase-invariant phase appears in the chargino mass matrix in
the minimal Supersymmetric Standard Model. We investigate in detail the
phenomenological impacts of the CP-odd complex phase in the production of light
charginos in annihilation. The values of the chargino masses and the
mixing angles, determining the size of the wino and higgsino components in the
chargino wave functions, are so sensitive to the CP-odd phase that the
constraints on the supersymmetric parameters based on the conventional
assumptions for the parameters are recommended to be re-evaluated including the
CP-odd phase.Comment: 9 pages, latex with 3 eps figur
Modeling of Ultra Low Capacitance Transient Voltage Suppression Diode for High ESD Protection
To improve key properties such as ultra-low capacitance (ULC) and high-voltage (HV) breakdown, we have performed a simulation work about transient voltage suppression (TVS) diodes. ULC-TVS diode was designed to employ a double deep trench to cut off the various parasitic effects that may degrade the device performance. The electrostatic discharge (ESD) protection is the targeting for the best applications in high-frequency and high-speed ICs. In this work, the device could present excellent performance in terms of very responsive ESD properties, high breakdown voltage, low leakage current, and very low capacitance level. The double trenches are aligned to the top electrode contact to restrict field crowding effects by the strong electric field intensity. The performance would be sufficient for the robust ESD nature up to IEC61000-4-2 (30 kV) and compatible with strong surge protection IEC61000-4-5 (10A). Their electrical properties have been evaluated for structure from simulation and the results are obtained at the device parameters. Several process of device design related effects on the electrical capability and can be optimized. Keywords: ULC-TVS diode, simulation (TCAD), characteristics, capacitance, ESD protection
Factorization and polarization in linearized gravity
We investigate all the four-body graviton interaction processes:
, , and with
as an elementary particle of spin less than two in the context of linearized
gravity except the spin-3/2 case. We show explicitly that gravitational gauge
invariance and Lorentz invariance cause every four-body graviton scattering
amplitude to be factorized. We explore the implications of this factorization
property by investigating polarization effects through the covariant density
matrix formalism in each four-body graviton scattering process.Comment: 45 pages, figures are included (uses pictex), RevTe
Factorization of gravitational Compton scattering amplitude in the linearized version of general relativity
Gravitational Compton scattering process with a massive fermion is studied in
the context of the linearized gravity. Gravitational gauge invariance and
graviton transversality cause the transition amplitude to be factorized into
that of scalar QED Compton scattering and that of fermion QED Compton
scattering with an overall kinematical factor. The factorization is shown
explicitly and its physical implications are discussed.Comment: 11 pages, 1 figure(not included), Revtex 3.0, SNUTP 93-2
Potential Residential Exposure to Toxics Release Inventory Chemicals during Pregnancy and Childhood Brain Cancer
BACKGROUND: Although the susceptibility of the developing fetus to various chemical exposures is well documented, the role of environmental chemicals in childhood brain cancer etiology is not well understood. OBJECTIVES: We aimed to evaluate whether mothers of childhood brain cancer cases had greater potential residential exposure to Toxics Release Inventory (TRI) chemicals than control mothers during pregnancy. METHODS: We included 382 brain cancer cases diagnosed at < 10 years of age from 1993 through 1997 who were identified from four statewide cancer registries. One-to-one matched controls were selected by random-digit dialing. Computer-assisted telephone interviews were conducted. Using residential history of mothers during pregnancy, we measured proximity to TRI facilities and exposure index, including mass and chemicals released. We calculated odds ratios (ORs) and 95% confidence intervals (CIs) using conditional logistic regression to estimate brain cancer risk associated with TRI chemicals. RESULTS: Increased risk was observed for mothers living within 1 mi of a TRI facility (OR = 1.66; 95% CI, 1.11–2.48) and living within 1 mi of a facility releasing carcinogens (OR = 1.72; 95% CI, 1.05–2.82) for having children diagnosed with brain cancer before 5 years of age, compared to living > 1 mi from a facility. Taking into account the mass and toxicity of chemical releases, we found a nonsignificant increase in risk (OR = 1.25; 95% CI, 0.67–2.34) comparing those with the lowest versus highest exposure index. CONCLUSIONS: Risk of childhood brain cancers may be associated with living near a TRI facility; however, this is an exploratory study and further studies are needed
Mechanism of Cisplatin-Induced Cytotoxicity Is Correlated to Impaired Metabolism Due to Mitochondrial ROS Generation
The chemotherapeutic use of cisplatin is limited by its severe side effects. In this study, by conducting different omics data analyses, we demonstrated that cisplatin induces cell death in a proximal tubular cell line by suppressing glycolysis-and tricarboxylic acid (TCA)/mitochondria-related genes. Furthermore, analysis of the urine from cisplatin-treated rats revealed the lower expression levels of enzymes involved in glycolysis, TCA cycle, and genes related to mitochondrial stability and confirmed the cisplatin-related metabolic abnormalities. Additionally, an increase in the level of p53, which directly inhibits glycolysis, has been observed. Inhibition of p53 restored glycolysis and significantly reduced the rate of cell death at 24 h and 48 h due to p53 inhibition. The foremost reason of cisplatin-related cytotoxicity has been correlated to the generation of mitochondrial reactive oxygen species (ROS) that influence multiple pathways. Abnormalities in these pathways resulted in the collapse of mitochondrial energy production, which in turn sensitized the cells to death. The quenching of ROS led to the amelioration of the affected pathways. Considering these observations, it can be concluded that there is a significant correlation between cisplatin and metabolic dysfunctions involving mROS as the major player.116224Ysciescopu
Altered resting-state connectivity in subjects at ultra-high risk for psychosis: an fMRI study
<p>Abstract</p> <p>Background</p> <p>Individuals at ultra-high risk (UHR) for psychosis have self-disturbances and deficits in social cognition and functioning. Midline default network areas, including the medial prefrontal cortex and posterior cingulate cortex, are implicated in self-referential and social cognitive tasks. Thus, the neural substrates within the default mode network (DMN) have the potential to mediate self-referential and social cognitive information processing in UHR subjects.</p> <p>Methods</p> <p>This study utilized functional magnetic resonance imaging (fMRI) to investigate resting-state DMN and task-related network (TRN) functional connectivity in 19 UHR subjects and 20 matched healthy controls. The bilateral posterior cingulate cortex was selected as a seed region, and the intrinsic organization for all subjects was reconstructed on the basis of fMRI time series correlation.</p> <p>Results</p> <p>Default mode areas included the posterior/anterior cingulate cortices, the medial prefrontal cortex, the lateral parietal cortex, and the inferior temporal region. Task-related network areas included the dorsolateral prefrontal cortex, supplementary motor area, the inferior parietal lobule, and middle temporal cortex. Compared to healthy controls, UHR subjects exhibit hyperconnectivity within the default network regions and reduced anti-correlations (or negative correlations nearer to zero) between the posterior cingulate cortex and task-related areas.</p> <p>Conclusions</p> <p>These findings suggest that abnormal resting-state network activity may be related with the clinical features of UHR subjects. Neurodevelopmental and anatomical alterations of cortical midline structure might underlie altered intrinsic networks in UHR subjects.</p
Pulse-shape discrimination between electron and nuclear recoils in a NaI(Tl) crystal
We report on the response of a high light-output NaI(Tl) crystal to nuclear
recoils induced by neutrons from an Am-Be source and compare the results with
the response to electron recoils produced by Compton scattered 662 keV
-rays from a Cs source. The measured pulse-shape discrimination
(PSD) power of the NaI(Tl) crystal is found to be significantly improved
because of the high light output of the NaI(Tl) detector. We quantify the PSD
power with a quality factor and estimate the sensitivity to the interaction
rate for weakly interacting massive particles (WIMPs) with nucleons, and the
result is compared with the annual modulation amplitude observed by the
DAMA/LIBRA experiment. The sensitivity to spin-independent WIMP-nucleon
interactions based on 100 kgyear of data from NaI detectors is estimated
with simulated experiments, using the standard halo model.Comment: 11page
Photoemission and x-ray absorption study of MgC_(1-x)Ni_3
We investigated electronic structure of MgC_(1-x)Ni_3 with photoemission and
x-ray absorption spectroscopy. Both results show that overall band structure is
in reasonable agreement with band structure calculations including the
existence of von Hove singularity (vHs)near E_F. However, we find that the
sharp vHs peak theoretically predicted near the E_F is substantially
suppressed. As for the Ni core level and absorption spectrum, there exist the
satellites of Ni 2p which have a little larger energy separation and reduced
intensity compared to the case of Ni-metal. These facts indicate that
correlation effects among Ni 3d electrons may be important to understand
various physical properties.Comment: 12 pages, 4 figure
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