Cloud Armor: A Conclusion Work on Trust Management System

Distributed computing gives Software as service (Saas) ,Platform as service(Paas) and Infrasrtucture as a service(Iaas).Cloud figuring condition having a few issues like protection and security. Trust administration is a standout amongst the most difficult issue. Shielding a specific cloud benefit from a few assaults like agreement attack(Such as client may give misdirecting criticism about specific cloud services)and Sybil attack(such as a solitary client can make numerous accounts..i.,e noxious user).In this paper we talk about cloudarmor that gives notoriety based trust administration to cloud administrations. A notoriety based trust administration system gives set of functionalities to convey Trust as a service(Taas) . Taas incorporates i)Zeroknowledge believability evidence convention to demonstrate validity of the consumers criticism and jam client security, ii)a validity show it will measures te validity of input to shield cloud administrations from malevolent client. what's more, iii)an accessibility model to deal with the accessibility of the trust administration

Knowledge, attitude and practice of menstrual hygiene among adolescent schoolgirls of rural area, Dakshina Kannada, India

Background: Adolescent girls constitute a vulnerable group not only with respect to their social status but also in relation to their health. Menstruation is accompanied by a cultural taboo in almost every society in the world. Although very common issue of everyday of life, menstruation is associated with many menstruations negative attitude in young girls. The young population is seen to be trapped and confused due to the different schools of thoughts at home and the outer world. This indicates an urgency to investigate girls, menstrual needs, to inform effective responses and educate them about the right strategies of menstrual hygiene, attitudes and practices. The aim of our study was to assess the knowledge, attitude and practices about menstrual hygiene among adolescent school girls from rural areas of Dakshina Kannada.Methods: This was a cross sectional study conducted from January 2020 to February 2020 among 130 secondary schools and high school girls of rural area of Dakshina Kannada, using predesigned questionnaire after obtaining informed consent.Results: In our study, most of the students had attained menarche by 12yrs of age. 86.15% were lacking primary knowledge about menstruation, and 80% of our participants had good knowledge about cleanliness of undergarments, and 65% of students knew that menstruation was a physiological phenomenon and 71% of the participants, still believed in the taboos and myths associated with menses and 30% were shy about carrying sanitary products to school. 63.85% participants still used cloth and most worrisome finding of our study is that 63% of our students did not feel comfortable to approach their family/elders/health care workers to solve their queries about menstruation.Conclusions: The study aimed at assessing the knowledge, attitude & practices of the adolescents regarding menstruation and menstrual hygiene. The low level of knowledge among participants is evident from their unpreparedness while entering menarche and their strong views of menstruation as social taboo can be judged from their various restrictions, owing to such strong socio-cultural beliefs and practices. Group discussions, media campaigns, sex education in schools are required to overcome taboo associated with menstruation.

Health and Wellness Product from Mangosteen (Garcinia mangostana L.) Rind: Bioactive Potentials

Mangosteen rind (MSR) (Garcinia mangostana L.) is a predominant component of the fruit contributing to 62% of the whole fruit. However, utilization of the same for the preparation of health products was not explored due to its sensorially less acceptable parameters. Differential extraction in different polarity solvents of MSR was done and evaluated their acceptability for product preparation.Current study thus is a detailed investigation on bioactivity profiling of MSR fraction and utilization of the same for health product preparation. Among various extracts, 70% ethanol (70%AE) yielded the maximum (15g/100g). Xanthone:Phenolic ratio was 1: 2.8, in 70%AE as opposed to hot water extract – HWE and 50% AE, which contained Xanthone:Phenolic ratio of 1:1.4/5. Higher the phenolic content obviously reduces the bitterness of Xanthones. 70% AE contained phenolics 60.08± 0.213 mg/g and xanthones 22.56± 0.317 mg/g. HPLC analysis revealed a spectrum of phenolic acids such as gallic, chlorogenic, caffeic, epicatechin, catechin and ferulic acids at various levels. Potent Free Radical Scavenging (FRS) activity, cytoprotectivity, DNA protectivity, H+K+ATPase inhibitory (PPAI) activities were observed in 70% AE. Gallic/tannic acid appear to contribute to antioxidant activity; while ferulic acid was responsible for PPAI activity in 70%AE. Among xanthones, although α- mangostin was the dominating component, gartanin, 8 deoxygartanin and 3-isomangostin contributed to FRS activity. The products were prepared from 70%AE which are sensorially acceptable. Data thus for the first time delineate the specific health beneficial role of both phenolic and xanthone constituents in MSR particularly with higher abundance of phenolics than xanthones

A mouse model with widespread expression of the C9orf72-linked glycine-arginine dipeptide displays non-lethal ALS/FTD-like phenotypes

Translation of the hexanucleotide G4C2 expansion associated with C9orf72 amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) produces five different dipeptide repeat protein (DPR) species that can confer toxicity. There is yet much to learn about the contribution of a single DPR to disease pathogenesis. We show here that a short repeat length is sufficient for the DPR poly-GR to confer neurotoxicity in vitro, a phenomenon previously unobserved. This toxicity is also reported in vivo in our novel knock-in mouse model characterized by widespread central nervous system (CNS) expression of the short-length poly-GR. We observe sex-specific chronic ALS/FTD-like phenotypes in these mice, including mild motor neuron loss, but no TDP-43 mis-localization, as well as motor and cognitive impairments. We suggest that this model can serve as the foundation for phenotypic exacerbation through second-hit forms of stress

EPHRINB2 Knockdown in Cervical Spinal Cord Preserves Diaphragm Innervation in a Mutant SOD1 Mouse Model of ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motor neuron loss. Importantly, non-neuronal cell types such as astrocytes also play significant roles in disease pathogenesis. However, mechanisms of astrocyte contribution to ALS remain incompletely understood. Astrocyte involvement suggests that transcellular signaling may play a role in disease. We examined contribution of transmembrane signaling molecule ephrinB2 to ALS pathogenesis, in particular its role in driving motor neuron damage by spinal cord astrocytes. In symptomatic SOD1G93A mice (a well-established ALS model), ephrinB2 expression was dramatically increased in ventral horn astrocytes. Reducing ephrinB2 in the cervical spinal cord ventral horn via viral-mediated shRNA delivery reduced motor neuron loss and preserved respiratory function by maintaining phrenic motor neuron innervation of diaphragm. EphrinB2 expression was also elevated in human ALS spinal cord. These findings implicate ephrinB2 upregulation as both a transcellular signaling mechanism in mutant SOD1-associated ALS and a promising therapeutic target

Derivations and Translations on Trellises

summary:G. Szász, J. Szendrei, K. Iseki and J. Nieminen have made an extensive study of derivations and translations on lattices. In this paper, the concepts of meet-translations and derivations have been studied in trellises (also called weakly associative lattices or WA-lattices) and several results in lattices are extended to trellises. The main theorem of this paper, namely, that every derivatrion of a trellis is a meet-translation, is proved without using associativity and it generalizes a well-known result of G. Szász

Mineral Composition of Four Edible Mushrooms

Two cultivated mushroom species, namely, Lentinula edodes and Pleurotus florida and two wild growing species Lentinus cladopus and Pleurotus djamor were studied for their mineral contents such as Ca, Mg, Na, K, Fe, Zn, Mn, Cu, Ni, Se, Pb, and Cd by Inductive Coupled Plasma Atomic Emission Spectroscopy (ICP-AES) and also Atomic Absorption Spectroscopy, (AAS). Phosphorus was estimated by spectrophotometric method. K, Ca, Na, and P were in higher concentrations ranging from 59.3 mg to 3634 mg, 8.27 mg–174.9 mg, 22.2 mg–327.4 mg, and 100.5 mg–769.9 mg/100 g dry weight respectively in the four mushroom species studied. Fe, Zn, Mg and Se were ranging from 6.27 mg to 35.3 mg, 1.58 mg–9.44 mg, 21.1 mg–40.7 mg and 0.048 mg–0.182 mg/100 g dry weight, respectively, amongst the mushroom species analyzed. However, Ni, Cu, and Mn contents showed relatively lower concentrations, whereas Pb and Cd were below detectable level. The mushrooms were safe for consumption, in accordance with the permissible tolerance limits of the estimated toxic metals. Implications of the mineral contents on mushroom nutritional value are highlighted