The Role of Information Provision as a Policy Instrument to Supplement Environmental Taxes: Empowering Consumers to Choose Optimally

The present paper examines, within a dynamic framework, the use of information provision as a policy instrument to supplement environmental taxation. We assume that at least a fraction of consumers do not posses the required information to make the optimal choices, and that their behavior at each time period depends on the accumulated stock of information. We show that, as the accumulated stock of information provision increases, both the optimal level of information provided at each period of time and the optimal tax rate decline over time. Our results provide strong evidence in support of information campaigns as a policy instrument to supplement traditional environmental policies. Information provision can shift the demand towards environmentally friendly products over time and thus, reduce the required level of the tax rate.Information Provision, Environmental Taxation

Strategic delegation in experimental duopolies with endogenous incentive contracts

Often, deviations of firm behavior from profit maximization are the result of managerial incentive contracts. We study the endogenous emergence of incentive contracts used by firm owners to delegate the strategic decisions of the firm. These contracts are linear combinations either of own firm's profits and revenues, or own and rival firms' profits. A two- and three-stage game are studied depending on whether owners commit or not to a certain contract type before setting the managerial incentives and the level of output to produce in the market. We report experimental results which confirm some of the predictions of the model, especially those concerning owners' preference for relative performance incentives over profit-revenue contracts. Neglected behavioral aspects are proposed as possible explanation of some divergence between the theory and the experimental evidence, more specifically the relation between contract terms and managers' output choicesExperimental economics; Oligopoly theory; Managerial delegation; Endogenous contracts.

United we stand: improving sentiment analysis by joining machine learning and rule based methods

In the past, we have succesfully used machine learning approaches for sentiment analysis. In the course of those experiments, we observed that our machine learning method, although able to cope well with figurative language could not always reach a certain decision about the polarity orientation of sentences, yielding erroneous evaluations. We support the conjecture that these cases bearing mild figurativeness could be better handled by a rule-based system. These two systems, acting complementarily, could bridge the gap between machine learning and rule-based approaches. Experimental results using the corpus of the Affective Text Task of SemEval ’07, provide evidence in favor of this direction. 1

The Total Solar Eclipse of March 2006: overview

International audienceThis paper provides an overview of integrated, multi-disciplinary effort to study the effects of a total solar eclipse on the environment, with special focus on the atmosphere. On the occasion of the 29 March 2006 total solar eclipse, visible over the Eastern Mediterranean, several research and academic institutes organised co-ordinated experimental campaigns, at different distances from the totality and in various environments in terms of air quality. The detailed results are presented in a number of scientific papers included in a Special Issue of Atmospheric Chemistry and Physics. The effects of the eclipse on the meteorology and the spectral solar radiation, the chemical response of the atmosphere to the abrupt "switch off" of the sun and the induced changes in the stratosphere and the ionosphere, have been among the issues covered. The rare event of a total solar eclipse provided the opportunity to evaluate 1-D and 3-D radiative transfer models (in the atmosphere and underwater), mesoscale meteorological, regional air quality and photochemical box models, against measurements. Within the challenging topics of this effort has been the investigation of eclipse impacts on ecosystems (field crops and marine plankton) and the identification of eclipse induced gravity waves, for the first time with simultaneous measurements at three altitudes namely the troposphere, the stratosphere and the ionosphere

Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1

Proteins with long, pathogenic polyglutamine (polyQ) sequences have an enhanced propensity to spontaneously misfold and self-assemble into insoluble protein aggregates. Here, we have identified 21 human proteins that influence polyQ-induced ataxin-1 misfolding and proteotoxicity in cell model systems. By analyzing the protein sequences of these modifiers, we discovered a recurrent presence of coiled-coil (CC) domains in ataxin-1 toxicity enhancers, while such domains were not present in suppressors. This suggests that CC domains contribute to the aggregation- and toxicity-promoting effects of modifiers in mammalian cells. We found that the ataxin-1–interacting protein MED15, computationally predicted to possess an N-terminal CC domain, enhances spontaneous ataxin-1 aggregation in cell-based assays, while no such effect was observed with the truncated protein MED15ΔCC, lacking such a domain. Studies with recombinant proteins confirmed these results and demonstrated that the N-terminal CC domain of MED15 (MED15CC) per se is sufficient to promote spontaneous ataxin-1 aggregation in vitro. Moreover, we observed that a hybrid Pum1 protein harboring the MED15CC domain promotes ataxin-1 aggregation in cell model systems. In strong contrast, wild-type Pum1 lacking a CC domain did not stimulate ataxin-1 polymerization. These results suggest that proteins with CC domains are potent enhancers of polyQ-mediated protein misfolding and aggregation in vitro and in vivo

Rare non-Wilms' tumors in children

We report our institutional experience of the management of 2 cases of rare non-Wilms' tumors; a rhabdoid tumor in a 17-month old boy and a clear cell sarcoma in a 5-year old girl. The two patients were treated with ifosfamide/carboplatin/etoposide (ICE) alternating with vincristine/doxorubicin/cyclophosphamide (VDC) and cyclophosphamide/etoposide (CE) alternating with vincristine/doxorubicin/cyclophosphamide (VDC) and radiotherapy, respectively. Both patients showed full response with no significant adverse events. At 2-year follow up, they are disease and relapse free. Although contemporary treatment regimens are very promising, multicenter collaborative studies are needed in order to define a standard treatment for non-Wilms' tumors