847 research outputs found
NIEL Dose Dependence for Solar Cells Irradiated with Electrons and Protons
The investigation of solar cells degradation and the prediction of its
end-of-life performance is of primary importance in the preparation of a space
mission. In the present work, we investigate the reduction of solar-cells'
maximum power resulting from irradiations with electrons and protons. Both GaAs
single junction and GaInP/GaAs/Ge triple junction solar cells were studied. The
results obtained indicate how i) the dominant radiation damaging mechanism is
due to atomic displacements, ii) the relative maximum power degradation is
almost independent of the type of incoming particle, i.e., iii) to a first
approximation, the fitted semi-empirical function expressing the decrease of
maximum power depends only on the absorbed NIEL dose, and iv) the actual
displacement threshold energy value (Ed=21 eV) accounts for annealing
treatments, mostly due to self-annealing induced effects. Thus, for a given
type of solar cell, a unique maximum power degradation curve can be determined
as a function of the absorbed NIEL dose. The latter expression allows one to
predict the performance of those solar cells in space radiation environment.Comment: To appear on the Proceedings of the 13th ICATPP Conference on
Astroparticle, Particle, Space Physics and Detectors for Physics
Applications, Villa Olmo (Como, Italy), 23--27 October, 2013, to be published
by World Scientific (Singapore
Nuclear and Non-Ionizing Energy-Loss for Coulomb Scattered Particles from Low Energy up to Relativistic Regime in Space Radiation Environment
In the space environment, instruments onboard of spacecrafts can be affected
by displacement damage due to radiation. The differential scattering cross
section for screened nucleus--nucleus interactions - i.e., including the
effects due to screened Coulomb nuclear fields -, nuclear stopping powers and
non-ionization energy losses are treated from about 50 keV/nucleon up to
relativistic energies.Comment: Accepted for publication in the Proceedings of the ICATPP Conference
on Cosmic Rays for Particle and Astroparticle Physics, Villa Olmo (Como,
Italy), 7--8 October, 2010, to be published by World Scientifi
Antiproton modulation in the Heliosphere and AMS-02 antiproton over proton ratio prediction
We implemented a quasi time-dependent 2D stochastic model of solar modulation
describing the transport of cosmic rays (CR) in the heliosphere. Our code can
modulate the Local Interstellar Spectrum (LIS) of a generic charged particle
(light cosmic ions and electrons), calculating the spectrum at 1AU. Several
measurements of CR antiparticles have been performed. Here we focused our
attention on the CR antiproton component and the antiproton over proton ratio.
We show that our model, using the same heliospheric parameters for both
particles, fit the observed anti-p/p ratio. We show a good agreement with
BESS-97 and PAMELA data and make a prediction for the AMS-02 experiment
Magnetospheric transmission function approach to disentangle primary from secondary cosmic ray fluxes in the penumbra region
[1] The AMS-01 observations (in June 1998, on board the space shuttle orbiter Discovery) have shown the presence of primary (PCR) and secondary (SCR) cosmic rays (most of them protons) at a low Earth orbit (about 400 km altitude). The SCRs are mostly created in interactions with the atmosphere by fast PCRs and can be trapped or become reentrant albedo particles. Some of them seem to be sufficiently energetic to populate the "penumbra region" above the local geomagnetic cutoff rigidity. A backtracking procedure of simulated protons entering the AMS-01 spectrometer has provided the fraction of allowed (and hence forbidden) trajectories of PCRs. Consequently, it has allowed the determination of the so-called transmission function (TF) which is able to describe the properties of the PCR transport from the Earth's magnetopause (i.e., the primary spectrum at 1 AU) to the atmosphere and finally the fluxes of the PCRs in the ten geomagnetic regions for AMS-01 observations. In the penumbra regions, the observed spectra of the AMS-01 geomagnetic regions have been found to be larger than those predicted for the PCRs in the penumbra region by means of the TF, i.e., some SCRs (mainly reentrant albedo protons) are also found to populate the rigidity regions above the local geomagnetic cutoff rigidity. The fraction of the secondary to overall particle flux in the penumbra region increases gradually as the geomagnetic latitude increases
Proton Modulation in the Heliosphere for Different Solar Conditions and Prediction for AMS-02
Spectra of Galactic Cosmic Rays (GCRs) measured at the Earth are the
combination of several processes: sources production and acceleration,
propagation in the interstellar medium and propagation in the heliosphere.
Inside the solar cavity the flux of GCRs is reduced due to the solar
modulation, the interaction which they have with the interplanetary medium. We
realized a 2D stochastic simulation of solar modulation to reproduce CR spectra
at the Earth, and evaluated the importance in our results of the Local
Interstellar Spectrum (LIS) model and its agreement with data at high energy.
We show a good agreement between our model and the data taken by AMS-01 and
BESS experiments during periods with different solar activity conditions.
Furthermore we made a prediction for the flux which will be measured by AMS-02
experiment.Comment: Accepted for publication in the Proceedings of the ICATPP Conference
on Cosmic Rays for Particle and Astroparticle Physics, Villa Olmo (Como,
Italy), 7-8 October, 2010, to be published by World Scientific (Singapore
Latitudinal Dependence of Cosmic Rays Modulation at 1 AU and Interplanetary-Magnetic-Field Polar Correction
The cosmic rays differential intensity inside the heliosphere, for energy
below 30 GeV/nuc, depends on solar activity and interplanetary magnetic field
polarity. This variation, termed solar modulation, is described using a 2-D
(radius and colatitude) Monte Carlo approach for solving the Parker transport
equation that includes diffusion, convection, magnetic drift and adiabatic
energy loss. Since the whole transport is strongly related to the
interplanetary magnetic field (IMF) structure, a better understanding of his
description is needed in order to reproduce the cosmic rays intensity at the
Earth, as well as outside the ecliptic plane. In this work an interplanetary
magnetic field model including the standard description on ecliptic region and
a polar correction is presented. This treatment of the IMF, implemented in the
HelMod Monte Carlo code (version 2.0), was used to determine the effects on the
differential intensity of Proton at 1\,AU and allowed one to investigate how
latitudinal gradients of proton intensities, observed in the inner heliosphere
with the Ulysses spacecraft during 1995, can be affected by the modification of
the IMF in the polar regions.Comment: accepted for publication inAdvances in Astronom
Zebrafish embryo extracts enhance 5-FU anti-cancer effects upon breast cancer cells
OBJECTIVE: The inhibition of the metastatic capability of cancer cells is a pivotal aim of current anticancer strategies. We investigated herein the anti-migrating and anti-invasive properties of Zebrafish embryo extracts (SL) - an integrative formula comprising morphogenetic factors extracted from zebrafish embryos - alone or in association with 5-Fluoro-Uracil (5-FU), when added to metastatic breast cancer cells (MDA-MB-231) and in normal epithelial breast cells (MCF10A) committed toward an inflammatory phenotype upon TGF-beta 1 stimulation.MATERIALS AND METHODS: Invasiveness, migrating capability, cytoskeleton architecture and related molecular factors involved in the epithelial-mesenchymal transition were studied after treatment with 5-FU, with and without SL.RESULTS: Remarkably, in both circumstances, embryo extracts amplify the migratory inhibition triggered by the anticancer drug 5-Fu. The fact that such an effect is noticed in normal as well as in cancerous cells suggests that the critical target of embryo extracts is specifically represented by the migrating/invasive phenotype. However, while 5-FU was unable in antagonizing the invasiveness of cancerous cells, the association with SL can significantly impair the invasive capability of tumor cells. These findings are noticeably associated with the reversion of the EMT phenotype in SL-treated cells, as documented by the contemporary downregulation of TCTP and some EMT-related molecular effectors, like alpha-SMA and Vimentin.CONCLUSIONS: Embryo fish extracts significantly counteract the migrating and invasive phenotype of cancerous and inflammatory breast cells treated with the chemotherapeutic drug 5-FU. The availability of a compound able to amplify 5-Fu activity while significantly hampering the invasive phenotype of breast cancer should provide invaluable benefits, namely if we consider that this compound is substantially deprived of side-effects
Suprathermal particle addition to solar wind pressure: possible influence on magnetospheric transmissivity of low energy cosmic rays?
Energetic (suprathermal) solar particles, accelerated in the interplanetary
medium, contribute to the solar wind pressure, in particular during high solar
activity periods. We estimated the effect of the increase of solar wind
pressure due to suprathermal particles on magnetospheric transmissivity of
galactic cosmic rays in the case of one recent solar event
- …