2,930 research outputs found
Power Allocation and Cooperative Diversity in Two-Way Non-Regenerative Cognitive Radio Networks
In this paper, we investigate the performance of a dual-hop block fading
cognitive radio network with underlay spectrum sharing over independent but not
necessarily identically distributed (i.n.i.d.) Nakagami- fading channels.
The primary network consists of a source and a destination. Depending on
whether the secondary network which consists of two source nodes have a single
relay for cooperation or multiple relays thereby employs opportunistic relay
selection for cooperation and whether the two source nodes suffer from the
primary users' (PU) interference, two cases are considered in this paper, which
are referred to as Scenario (a) and Scenario (b), respectively. For the
considered underlay spectrum sharing, the transmit power constraint of the
proposed system is adjusted by interference limit on the primary network and
the interference imposed by primary user (PU). The developed new analysis
obtains new analytical results for the outage capacity (OC) and average symbol
error probability (ASEP). In particular, for Scenario (a), tight lower bounds
on the OC and ASEP of the secondary network are derived in closed-form. In
addition, a closed from expression for the end-to-end OC of Scenario (a) is
achieved. With regards to Scenario (b), a tight lower bound on the OC of the
secondary network is derived in closed-form. All analytical results are
corroborated using Monte Carlo simulation method
Primary Epstein-Barr virus infection in a 40-day-old infant
Most cases of primary Epstein-Barr virus (EBV) infection during infancy and early childhood are mild or subclinical; therefore, the diagnosis of an EBV infection is not performed easily in this age group. Infectious mononucleosis (IM) is rarely reported during infancy. We report a 40-day-old infant with cervical node enlargement, cough, and coryza symptoms who was finally identified as having a case of primary IM based on the patient's clinical features and serological tests. © 2013 - IOS Press and the authors. All rights reserved
Avalanche frontiers in dissipative abelian sandpile model as off-critical SLE(2)
Avalanche frontiers in Abelian Sandpile Model (ASM) are random simple curves
whose continuum limit is known to be a Schramm-Loewner Evolution (SLE) with
diffusivity parameter . In this paper we consider the dissipative
ASM and study the statistics of the avalanche and wave frontiers for various
rates of dissipation. We examine the scaling behavior of a number of functions
such as the correlation length, the exponent of distribution function of loop
lengths and gyration radius defined for waves and avalanches. We find that they
do scale with the rate of dissipation. Two significant length scales are
observed. For length scales much smaller than the correlation length, these
curves show properties close to the critical curves and the corresponding
diffusivity parameter is nearly the same as the critical limit. We interpret
this as the ultra violet (UV) limit where corresponding to .
For length scales much larger than the correlation length we find that the
avalanche frontiers tend to Self-Avoiding Walk, the corresponding driving
function is proportional to the Brownian motion with the diffusion parameter
corresponding to a field theory with . This is the infra
red (IR) limit. Correspondingly the central charge decreases from the IR to the
UV point.Comment: 11 Pages, 6 Figure
Anthropometric indices in individuals infected with ascaris lumbericoids in Iran
Context: Ascaris Lumbericoids infection is more common in children and teenagers and in areas with poor sanitation or crowded living conditions. Largest of all the parasites inhabiting the human intestine it is also the most common of parasitic infections in developing countries. It has been reported to infect about one-fourth of the world population. Chronic ascariasis has been reported to adversely effect the growth rate and anthropometric indices in infected individuals of growing age. Aims: The goal of this research was to evaluate the anthropometric indices in individuals infected with Ascaris in Hamedan province of Iran. Settings and Design: This was a descriptive cross sectional study. Methods and Material: Six hundred fourteen randomly selected individuals who were inhabitants of Hamedan province of Iran were chosen for this study. Stool samples of these individuals were collected and then experimented with Formel-Ether method to determine Ascaris Lumbericoids infection. Height and weight of these individuals were measured and compared with the indices related to NCHS. Demographic information of these individuals was entered into questionnaires and ultimately was analyzed with SPSS software. Results: Out of the total study population, 16.5% of individuals were found to be infected with Ascaris. Out of the individuals infected with Ascaris, 1% were underweight. In the age groups of 6-10, 11-15, 16-20 years, 3.5%, 5.1% and 3.5% were found to be suffering from malnutrition, respectively. Conclusion: Malabsorption in children might result in malnutrition. In this study, few individuals infected with Ascaris had malnutrition, thus Ascaris infection may not be an important cause of malnutrition among children in our area
Multivariate Modeling of Cytochrome P450 Enzymes for 4- Aminoquinoline Antimalarial Analogues using Genetic- Algorithms Multiple Linear Regression
Purpose: To develop QSAR modeling of the inhibition of cytochrome P450s (CYPs) by chloroquine and a new series of 4-aminoquinoline derivatives in order to obtain a set of predictive in-silico models using genetic algorithms-multiple linear regression (GA-MLR) methods.Methods: Austin model 1 (AM1) semi-empirical quantum chemical calculation method was used to find the optimum 3D geometry of the studied molecules. The relevant molecular descriptors were selected by genetic algorithm-based multiple linear regression (GA-MLR) approach. In silico predictive models were generated to predict the inhibition of CYP 2B6, 2C9, 2C19, 2D6, and 3A4 isoforms using a set of descriptors.Results: The results obtained demonstrate that our model is capable of predicting the potential of new drug candidates to inhibit multiple CYP isoforms. A cross-validated Q2 test and external validation showed that the models were robust. By inspection of R2pred, and RMSE test sets, it can be seen that the predictive ability of the different CYP models varies considerably.Conclusion: Apart from insights into important molecular properties for CYP inhibition, the findings may also guide further investigations of novel drug candidates that are unlikely to inhibit multiple CYP sub-types.Keywords: Antimalarial, Chloroquine, Cytochrome P450, Genetic algorithm-based multiple linear regression, QSAR
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