Diagnostics and correction of vestibular, autonomic and vascular dysfunctions on the background of degenerative changes in the cervical spin

Studies in 82 patients were aimed at optimizing the diagnosis and treatment of vestibular dysfunctions with vegetative-vascular disorders during degenerative changes in the cervical spine.The main symptoms of vestibulopathy were dizziness as well as their provoking and related causes. Obtained objective state data of the vestibular analyzer using the integrative index of ataxia, the state of autonomic characteristics, data of the psychoemotional and cognitive sphere. The author's method of treating such conditions using a complex of vegetotropic, vascular, nootropic drugs, as well as intranasal electrophoresis, was used. Positive results were obtained for this type of therapy for vestibulopathy and autonomic vascular disorders

The Universality of Initial Conditions for Globular Cluster Formation

We investigate a simple model for globular cluster (GC) formation. We simulate the violent relaxation of initially homogeneous isothermal stellar spheres and show that it leads to the formation of clusters with radial density profiles that match the observed profiles of GCs. The best match is achieved for dynamically unevolved clusters. In this model, all the observed correlations between global GC parameters are accurately reproduced if one assumes that all the clusters initially had the same value of the stellar density and the velocity dispersion. This suggests that the gas which formed GCs had the same values of density and temperature throughout the universe.Comment: 12 pages, 4 figures, 1 table. Accepted for publication in ApJ Letter

Possibility of therapy of acute ischemic stroke by polyphenols of flavonoid group

Objective - to study neuroprotective effect of Quercetin in ischemia-reperfusion injury in acute ischemic stroke. Materials and methods. The study included 98 patients with acute ischemic stroke. All patients: main and control group, received standard treatment in accordance with the clinical protocol order Ministry of Health of Ukraine from 03.08.2012, № 602. Patients of the main group (n=68) on the back of the base further treatment was administered quercetin (Corvitin lyophilisate injection solution) course of 10 days according to the scheme: 500 mg of the drug diluted in 100 ml of 0.9% of the physiological solution intravenously twice a day for the first five days and once a day for the next five days. Patients in the control group (n=30) - quercetin is not appointed. Assessment by GCS, NIHSS, Barthel served in the 1st, 3rd, 5th, 10th day of the disease. Results. Simultaneously with the standard treatment, intravenous administration of quercetin, positively influenced the regression of focal neurological symptoms on the NIHSS and Barthel scales in patients with acute ischemic stroke, increased the proportion of patients in the consciousness or with its minor impairments in the GCS, ie contributed to an earlier “awakening” in acute ischemic stroke. Conclusions. Neuroprotective effect of quercetin (Corvitin lyophilisate injection solution) can be explained by its polytropic, antioxidant, anti-inflammatory, membrane-stabilizing effect in ischemia-reperfusion

Constraining global properties of the Draco dwarf spheroidal galaxy

By fitting a flexible stellar anisotropy model to the observed surface brightness and line-of-sight velocity dispersion profiles of Draco we derive a sequence of cosmologically plausible two-component (stars + dark matter) models for this galaxy. The models are consistent with all the available observations and can have either cuspy Navarro-Frenk-White or flat-cored dark matter density profiles. The dark matter halos either formed relatively recently (at z~2...7) and are massive (up to ~5x10^9 M_Sun), or formed before the end of the reionization of the universe (z~7...11) and are less massive (down to ~7x10^7 M_Sun). Our results thus support either of the two popular solutions of the "missing satellites" problem of Lambda cold dark matter cosmology - that dwarf spheroidals are either very massive, or very old. We carry out high-resolution simulations of the tidal evolution of our two-component Draco models in the potential of the Milky Way. The results of our simulations suggest that the observable properties of Draco have not been appreciably affected by the Galactic tides after 10 Gyr of evolution. We rule out Draco being a "tidal dwarf" - a tidally disrupted dwarf galaxy. Almost radial Draco orbits (with the pericentric distance <15 kpc) are also ruled out by our analysis. The case of a harmonic dark matter core can be consistent with observations only for a very limited choice of Draco orbits (with the apocentric-to-pericentric distances ratio of <2.5).Comment: 18 pages, 14 figures; accepted by Ap

Globular Clusters with Dark Matter Halos. II. Evolution in Tidal Field

In this second paper in our series, we continue to test primordial scenarios of globular cluster formation which predict that globular clusters formed in the early universe in the potential of dark matter minihalos. In this paper we use high-resolution N-body simulations to model tidal stripping experienced by primordial dark-matter dominated globular clusters in the static gravitational potential of the host dwarf galaxy. We test both cuspy Navarro-Frenk-White (NFW) and flat-core Burkert models of dark matter halos. Our primordial globular cluster with an NFW dark matter halo survives severe tidal stripping, and after 10 orbits is still dominated by dark matter in its outskirts. Our cluster with Burkert dark matter halo loses almost all its dark matter to tidal stripping, and starts losing stars at the end of our simulations. The results of this paper reinforce our conclusion in Paper I that current observations of globular clusters are consistent with the primordial picture of globular cluster formation.Comment: 12 pages, 9 figures. Astrophysical Journal, in pres

On the origin of the neutral hydrogen supershells: the ionized progenitors and the limitations of the multiple supernovae hypothesis

Here we address the question whether the ionized shells associated with giant HII regions can be progenitors of the larger HI shell-like objects found in the Milky Way and other spiral and dwarf irregular galaxies. We use for our analysis a sample of 12 HII shells presented recently by Rela\~no et al. (2005, 2007). We calculate the evolutionary tracks that these shells would have if their expansion is driven by multiple supernovae explosions from the parental stellar clusters. We find, contrary to Rela\~no et al. (2007), that the evolutionary tracks of their sample HII shells are inconsistent with the observed parameters of the largest and most massive neutral hydrogen supershells. We conclude that HII shells found inside giant HII regions may represent the progenitors of small or intermediate HI shells, however they cannot evolve into the largest HI objects unless, aside from the multiple supernovae explosions, an additional energy source contributes to their expansion.Comment: Accepted for publication in ApJ, tentatively scheduled for the ApJ July 1, 2008, v681n1 issue. 19 pages, 4 figure

Automatic Detection of Expanding HI Shells Using Artificial Neural Networks

The identification of expanding HI shells is difficult because of their variable morphological characteristics. The detection of HI bubbles on a global scale therefore never has been attempted. In this paper, an automatic detector for expanding HI shells is presented. The detection is based on the more stable dynamical characteristics of expanding shells and is performed in two stages. The first one is the recognition of the dynamical signature of an expanding bubble in the velocity spectra, based on the classification of an artificial neural network. The pixels associated with these recognized spectra are identified on each velocity channel. The second stage consists in looking for concentrations of those pixels that were firstly pointed out, and to decide if they are potential detections by morphological and 21-cm emission variation considerations. Two test bubbles are correctly detected and a potentially new case of shell that is visually very convincing is discovered. About 0.6% of the surveyed pixels are identified as part of a bubble. These may be false detections, but still constitute regions of space with high probability of finding an expanding shell. The subsequent search field is thus significantly reduced. We intend to conduct in the near future a large scale HI shells detection over the Perseus Arm using our detector.Comment: 39 pages, 11 figures, accepted by PAS

HIIphot: Automated Photometry of HII Regions Applied to M51

We have developed a robust, automated method, hereafter designated HIIphot, which enables accurate photometric characterization of HII regions while permitting genuine adaptivity to irregular source morphology. HIIphot utilizes object-recognition techniques to make a first guess at the shapes of all sources then allows for departure from such idealized ``seeds'' through an iterative growing procedure. Photometric corrections for spatially coincident diffuse emission are derived from a low-order surface fit to the background after exclusion of all detected sources. We present results for the well-studied, nearby spiral M51 in which 1229 HII regions are detected above the 5-sigma level. A simple, weighted power-law fit to the measured H-alpha luminosity function (HII LF) above log L_H-alpha = 37.6 gives alpha = -1.75+/-0.06, despite a conspicuous break in the HII LF observed near L_H-alpha = 10^38.9. Our best- fit slope is marginally steeper than measured by Rand (1992), perhaps reflecting our increased sensitivity at low luminosities and to notably diffuse objects. HII regions located in interarm gaps are preferentially less luminous than counterparts which constitute M51's grand-design spiral arms and are best fit with a power-law slope of alpha = -1.96+/-0.15. We assign arm/interarm status for HII regions based upon the varying surface brightness of diffuse emission as a function of position throughout the image. Using our measurement of the integrated flux contributed by resolved HII regions in M51, we estimate the diffuse fraction to be approximately 0.45 -- in agreement with the determination of Greenawalt et al. (1998). Automated processing of degraded datasets is undertaken to gauge systematic effects associated with limiting spatial resolution and sensitivity.Comment: 41 pages, 14 figures, Postscript version with high-resolution figures at ftp://ftp.aoc.nrao.edu/staff/dthilker/preprint

To the problems of modeling the brain ischemia in small animals

In the review article the problems of modeling cerebral ischemia in small mammals are consecrated. The advantages of experimental studies that are based on the similarity of the blood circulation of the brain in humans and animals are indicated. Classification of experimental models for the study of acute and chronic disorders of cerebral circulation, mechanisms of their development and preclinical approbation of new drugs is given. The authors indicate that all experimental models of brain ischemia can be divided into two groups: to study risk factors and pathophysiological studies of brain ischemia. And in the second case, the models of focal and global ischemia are described. In conclusion, the authors point out the difficulties and shortcomings of certain methods of ischemia reproduction, which await researchers to solve the above problems