Performance of Regional Rural Banks after Amalgamation in India: Progress and Prospects

For the past three decades India's banking system has several outstanding achievements to its credit. The most striking is its extensive reach. It is no longer confined to only metropolitans or cosmopolitans in India. In fact, Indian banking system has reached even to the remote corners of the country. This is one of the main reasons for India's growth process. The government's regular policy for Indian banks since 1969 has paid rich dividends with the nationalization of 14 major private banks of India. Regional Rural Banks started their development process on 2 October 1975 with the formation of a single bank—Prathama Grameen Bank. The RRBs mobilize financial resources from rural/semi-urban areas and grant loans and advances mostly to small and marginal farmers, agricultural labourers and rural artisans. The area of operation of RRBs is limited to the area as notified by GoI covering one or more districts in the State. In this context, the present study is an attempt to examine the impact of amalgamation on physical performance of RRBs during post-amalgamation period

STERILE PARENTERAL PRODUCTS: A NARRATIVE APPROACH

One of the first group’s toaddress these patient safety issues was the NationalCoordinating Committee on Large Volume Parenteral (NCCLVP). Parenteral medications are products which are introduced in a manner which circumvents the body’s most protective barriers, the skin and mucous membranes, and, therefore, must be “essentially†free of biological contamination.  Most are injected or placed into the body tissues and do not pass thru the liver before entering the bloodstream. This can include injections, topical and inhalation routes. Generally in pharmacy, parenteral refers to injection and the topical and inhalation routes are separated into their own routes of administration. NCCLVP was established by the US Pharmacopeia Convention, Inc., and subsequently developedand recommended standards of practice for the preparation, labeling, and quality assurance of hospital pharmacyadmixture services. Parenteral administration of drug is often critical and associated with problems such as limited number of acceptable excipients, stringent requirements of aseptic production process, safety issues, and patient noncompliance. Still this route maintains its value due to special advantages like quicker onset of action in case of emergency; target the drug quickly to desired site of action, prevention of first pass metabolism etc. This review highlightsformulation of parenteral product and advanced techniques involved in parenteral products.   Keywords: NCCLVP, LVP, Aseptic area, GMP etc

A overview: non-steroidal anti-inflammatory drugs and mechanisms

The inflammatory response represents a generalized response to infection or tissue damage and is designed to remove cellular debris, to localize invading organisms and arrest the spread of infection. NSAIDS are metabolized primarily in the liver. They vary in their half-lives and bioavailability. Given the multitude of available NSAIDs, the variability of their half-lives allows for different dosing regimens. The fluid in the inflamed area is known as inflammatory exudates, commonly called as pus. These exudates contain dead cells and debris in addition to body fluids. The inflammatory response is characterized by the following symptoms: Reddening of the localized area, swelling, pain and elevated temperature. Reddening results from capillary dialation that allows more blood to flow to the damaged tissue. Elevated temperature results from capillary dialation which permits increased blood flow through these vessels, with associated high metabolic activities of neutrophils and macrophages. The release of histamine from mast cells during antigen antibody reactions is well known, as is its involvement in the inflammatory response to skin injury. The present review focused on list and precautions of NSAID with its typed and classification, Analgesic activity study, histamine