Differential diagnosis of perinatal hypophosphatasia: radiologic perspectives

Perinatal hypophosphatasia (HPP) is a rare, potentially life-threatening, inherited, systemic metabolic bone disease that can be difficult to recognize in utero and postnatally. Diagnosis is challenging because of the large number of skeletal dysplasias with overlapping clinical features. This review focuses on the role of fetal and neonatal imaging modalities in the differential diagnosis of perinatal HPP from other skeletal dysplasias (e.g., osteogenesis imperfecta, campomelic dysplasia, achondrogenesis subtypes, hypochondrogenesis, cleidocranial dysplasia). Perinatal HPP is associated with a broad spectrum of imaging findings that are characteristic of but do not occur in all cases of HPP and are not unique to HPP, such as shortening, bowing and angulation of the long bones, and slender, poorly ossified ribs and metaphyseal lucencies. Conversely, absent ossification of whole bones is characteristic of severe lethal HPP and is associated with very few other conditions. Certain features may help distinguish HPP from other skeletal dysplasias, such as sites of angulation of long bones, patterns of hypomineralization, and metaphyseal characteristics. In utero recognition of HPP allows for the assembly and preparation of a multidisciplinary care team before delivery and provides additional time to devise treatment strategies

Seasonal abundance and host use patterns of seven Bactrocera Macquart species (Diptera: Tephritidae) in Thailand and Peninsular Malaysia

Freely access on publisher website Based on extensive male trapping, information is presented on the distribution and seasonal abundance of six Bactrocera species in Thailand and Peninsular Malaysia. Bactrocera dorsalis and B. correcta were trapped in northern and central Thailand, B. papayae, B. carambolae and B. umbrosa were restricted to southern Thailand and Malaysia, while B. cucurbitae was widespread, although more abundant in the north. Bactrocera dorsalis, B. papayae and B. correcta exhibited unimodal patterns of population abundance, with populations peaking between June and September depending on species and locality. Bactrocera carambolae, B. cucurbitae and B. umbrosa showed no clear patterns in their population modalities, varying between regions. Based on fruit rearing work undertaken in northern and southern Thailand, information on host use patterns is also provided for the above six species, plus B. latifrons. Bactrocera umbrosa, B. latifrons and B. cucurbitae are confirmed as oligophagous on Artocarpus spp., Solanum spp. and cucurbit spp., respectively. Species of the B. dorsalis complex (B. dorsalis, B. carambolae, B. papayae) and B. correcta, although with a very wide potential host range, were predominantly reared from a small number of hosts, including Terminalia catappa, Psidium guajava, Syzygium samarangense and Averrhoa carambola. The number of flies reared from such hosts were generally in excess of the proportion of that fruit in regional samples, implying that even though the flies are polyphagous species, not all hosts are used equally

Host plant records for fruit flies (Diptera: Tephritidae) in Southeast Asia

Plant records, derived largely from field studies in Thailand and Malaysia from 1986-94, are provided for 131 species of Southeast Asian Tephritidae