79 research outputs found
Phase II trial of isotonic fluid resuscitation in Kenyan children with severe malnutrition and hypovolaemia
Bioimpedance index for measurement of total body water in severely malnourished children: Assessing the effect of nutritional oedema
Causal impact of malnutrition on mortality among adults hospitalized for medical illness in sub-Saharan Africa: what is the role of severe sepsis?
PP058—New medicines and development strategies necessitates change in lifelong education of clinical pharmacology
Three compartment bioimpedance spectroscopy in the nutritional assessment and the outcome of patients with advanced or end stage kidney disease: What have we learned so far?
Determination of MTX levels by differential pulse polarography (DPP) in clinical practice
THE PHARMACOKINETICS OF N-[C-14-FORMYL]-LEUROSINE IN HUMANS
N-Formyl-leurosine labeled with 14C in the formyl group was administered to six patients with malignant disease, and the pharmacokinetic behavior of the drug was determined. Chromatographic studies on plasma showed the presence of unchanged drug and 7 metabolites. No metabolites were found in the urine. The plasma decay curve of the unchanged drug was biphasic with half-life values of t1 2α = 18.6 min and t1 2β = 4.28 hr. Within 72 hr only 30-40% of the radioactivity could be recovered in urine and feces in 5 patients. One patient consumed laxatives during the treatment. In this case 95% of the 14C-dose was recovered. The contribution made by fecal elimination was 80%. © 1981
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