In vitro regeneration of Momordica dioica (Roxb.)

Momordica dioica, Roxb. (Family: Cucurbitaceae) commonly called as Kartoli, is an important medicinal plant, which has remained unexplored from the commercial point of view. Considering its scarce availability and the medicinal importance, in vitro cultures were established. Traditionally, M. dioica has been propagated mainly through its tuberous roots and less commonly by seeds. Germination through seeds is very difficult or impossible because of hard seed coat. As an alternative to traditional methods tissue culture offers an efficient method for propagation of M. dioica. Mature seeds were used for the regeneration of M. dioica. The decoated seeds of M. dioica were cultured on Murashige and Skoog basal medium (MS medium) supplemented with various combinations of Auxins (á – naphthaleneacetic acid) and Cytokinins (N6 - benzyl adenine). MS basal medium supplemented with 4.44 µM and 8.88 µM N6 - benzyl adenine (BA) gave rise to maximum number of shoots in 7-8 weeks. In vitro grown shoots were sub cultured on MS medium supplemented with different concentrations of indole-3-butyric acid (IBA) for root initiation. MS medium with 0.049mM indole-3-butyric acid (IBA) showed rooting in 45 days. The regenerated plantlets were successfully hardened in vermiculite

A Polarization Study of 3 Blazars using the uGMRT at ~600 MHz

We present results from our radio polarimetric study with the upgraded Giant Metrewave Radio Telescope (uGMRT) at Band 4 (550-850 MHz) of 3 blazars: radio-loud quasars 3C390.3, 4C71.07 and BL Lac object 1ES 2344+514. The aim of this study was (i) to carry out a feasibility study for Band 4 polarization with the uGMRT, and (ii) to compare and contrast the kpc-scale polarization properties between the blazar sub-classes. We have detected linear polarization in all the three sources. The degree of linear polarization in the cores of the two quasars is higher than in the BL Lac object, consistent with similar differences observed on parsec-scales in blazars. The highest fractional polarization of 15% is observed in the hotspot region of 3C390.3, which also shows extended polarized lobe structures. 1ES 2344+514 shows a core-halo structure whereas 4C71.07 remains unresolved. A rotation of polarization electric vectors along the northern hotspot of 3C390.3, and the core of 1ES 2344+514, suggest jet bending. Greater depolarization in the southern lobe of 3C390.3 compared to the northern lobe indicates the presence of the `Laing-Garrington effect'. Multi-frequency uGMRT polarimetric data are underway to study the kpc-scale rotation measures across these sources in order to look for differences in the surrounding media.Comment: 13 pages, 6 figures, accepted by Journal of Astrophysics and Astronom

A Kpc-scale Radio Polarization Study of PG BL Lacs with the uGMRT

We present here uGMRT band 4 (~650MHz) polarization images of 8 BL~Lac objects belonging to the Palomar-Green (PG) `blazar' sample. A large fraction of the sources (~63%) reveal core-halo radio structures with most of the polarization detected in the inner core-jet regions. PG1101+385 and PG2254+075 exhibit a `spine-sheath structure' in polarization. The core-halo and `spine-sheath' structures are consistent with the Unified Scheme suggestion that BL~Lacs are the pole-on beamed counterparts of Fanaroff-Riley (FR) type I radio galaxies. PG1418+546 and PG0851+203 (OJ287) show the presence of terminal hotspots similar to FR type II radio galaxies. They were also found to be low-spectrally peaked BL Lacs, supportive of the `blazar envelope' scenario for BL~Lacs and quasars. Fractional polarization ranges from 1-13% in the cores and 2-26% in the inner jets/lobes of the sample BL Lacs. Compared to the varied radio morphology of quasars from the PG `blazar' sample, the BL~Lacs appear to be less diverse. A comparison of the inferred core magnetic (B-) field structures on arcsec- (kpc-) scales w.r.t. the Very Long Baseline Interferometry (VLBI) jet direction does not reveal any preferred orientation, suggesting that if large-scale ordered B-fields exist, they do so on scales smaller than probed by the current observations. However, the presence of polarized emission on arcsec-scales suggests that any mixing of thermal plasma with the synchrotron emitting plasma is insufficient to fully depolarize the emission via the internal depolarization process.Comment: 17 pages; 12 figures; MNRAS accepte

Artificial intelligence in public health dentistry

The creation of the relevant technology must be driven by educational demands. Even so, the human factor must always be taken into consideration. Exciting new technology and potent cures will continue to be produced by scientific research. The capacity of a digital computer, computer-controlled robot to carry out actions closely identified with intelligent beings is known as artificial intelligence (AI). The evolution of AI has been clearly accelerating over the past ten years, and dentistry has not been an exception. Dental AI is important for diagnosing patients, storing patient data, and evaluating genetic information to improve patient treatment. This applies particularly to oral medicine and radiography. A good understanding of technology adaption will not only contribute to better and more accurate patient care but will also lighten the workload of the physician. The need for sophisticated software to compute this data has arisen due to the massive growth in documented information as well as patient data. A new age in dentistry has emerged as a result of the convergence of artificial intelligence and digitization, and the field\u27s prospects for the future look quite bright

A Polarimetric Study of 9 PG Quasars with the VLA

We present polarization images of 9 radio-loud (RL) quasars from the VLA B-array at 6 GHz. These quasars belong to the Palomar-Green (PG) "blazar" sample comprising 16 RL quasars and 8 BL Lac objects. Extensive polarization is detected in the cores, jets and lobes of all the quasars, with cores primarily displaying magnetic (B-) fields transverse to, and jets displaying fields aligned with the jet direction. Hotspots display either transverse B-fields signifying B- field compression at terminal shocks or more complex structures. The fractional polarization in the cores ranges from 1-10% and jets/lobes from 10-40%. Several of the quasars show distorted or hybrid FRI/FRII radio morphologies with indications of restarted AGN activity. We attribute this to the optical/UV selection criteria of the PG sample that remains unbiased at radio frequencies. The in-band spectral indices of the radio cores are relatively flat while they are steep in the hotspots. This is consistent with the polarization structures where the hotspots appear to be locations of jet bends or bow-shocks. We present global properties for the entire PG "blazar" sample. We find that jet powers correlate with accretion rates for the quasars; higher accretion rates result in more powerful radio jets. A correlation between the radio core fractional polarization and the 150 MHz total radio luminosity for the 9 quasars studied here may imply that more organized B-fields at the jet bases lead to higher core fractional polarization and to more powerful radio jets.Comment: 24 pages, 21 figures, MNRAS accepte

Absence of calcium‐independent phospholipase A2β impairs platelet‐activating factor production and inflammatory cell recruitment in Trypanosoma cruzi‐infected endothelial cells

Both acute and chronic phases of Trypanosoma cruzi (T. cruzi) infection are characterized by tissue inflammation, mainly in the heart. A key step in the inflammatory process is the transmigration of inflammatory cells across the endothelium to underlying infected tissues. We observed increased arachidonic acid release and platelet‐activating factor (PAF) production in human coronary artery endothelial cells (HCAEC) at up to 96 h of T. cruzi infection. Arachidonic acid release is mediated by activation of the calcium‐independent phospholipase A(2) (iPLA(2)) isoforms iPLA(2)β and iPLA(2)γ, whereas PAF production was dependent upon iPLA(2)β activation alone. Trypanosoma cruzi infection also resulted in increased cell surface expression of adhesion molecules. Increased adherence of inflammatory cells to T. cruzi‐infected endothelium was blocked by inhibition of endothelial cell iPLA(2)β or by blocking the PAF receptor on inflammatory cells. This suggests that PAF, in combination with adhesion molecules, might contribute to parasite clearing in the heart by recruiting inflammatory cells to the endothelium

Tissue rotation of the Xenopus anterior–posterior neural axis reveals profound but transient plasticity at the mid-gastrula stage

The establishment of anterior-posterior (AP) regional identity is an essential step in the appropriate development of the vertebrate central nervous system. An important aspect of AP neural axis formation is the inherent plasticity that allows developing cells to respond to and recover from the various perturbations that embryos continually face during the course of development. While the mechanisms governing the regionalization of the nervous system have been extensively studied, relatively less is known about the nature and limits of early neural plasticity of the anterior-posterior neural axis. This study aims to characterize the degree of neural axis plasticity i