7 research outputs found
Preparation and Characterization of Electrospun PCL/Silk Fibroin Scaffolds
Natural polymer-based scaffolds are generally considered as favourable matrices for the adhesion and growth of cells in tissue repair. One of the most popular materials in
this respect is silk fibroin, known for its wide usage in biomedical applications. This work focuses on the development of electrospun scaffolds based on poly(ε-caprolactone) (PCL) and silk fibroin (SF) evaluated regarding the SF effect on their morphology, surface wetting ability, thermal properties, and HaCaT model cell line biocompatibility. The study revealed that the lowest PCL/SF concentration resulted in highest bead-like morphology formation, relatively thick fibers with the presence of random beads in the case of PCL, while uniform and thinner fibers in the case of increasing PCL/SF content scaffolds. The addition of SF reduced the degree of crystallinity in the PCL due to the less organized crystal structure, and decreased its thermal stability. Both SEM and MTT analyses showed cell presence on all scaffolds three days after cell seeding. Although SF improved PCL hydrophilicity, as shown quantitatively by the MTT assay for improved cytocompatibility properties, more structured electrospun PCL/SF scaffold strategies are required.
This work is licensed under a Creative Commons Attribution 4.0 International License
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Geodetic Source Modeling of the 2019 Mw 6.3 Durrës, Albania, Earthquake: Partial Rupture of a Blind Reverse Fault
We address geometric and kinematic properties of the Mw 6.3 26 November 2019 Durrës earthquake, the strongest earthquake in Albania in the past 40 years. Using coseismic surface displacements from Sentinel-1 Differential Interferometric Synthetic Aperture Radar (DInSAR) and nearby Global Navigational Satellite System (GNSS) stations, we invert for the geometry and slip of the causative fault. We find that both a steep SW-dipping fault (dip 71°) and a shallow NE-dipping fault (dip 15°) can fit the data equally well. However, the slip on the SW-dipping fault occurs at depths 11–23 km, similar to the depths of the mainshock and aftershock seismicity, and thus, we prefer that model. The location of our preferred fault plane correlates with the mapped SW-dipping backthrust, the Vore fault. The fault rupture did not reach the surface, which implies that an updip stress propagation onto the unruptured shallow portion of the Vore fault and its secondary structures pose an increased seismic hazard for cities in Albania, including the capital, Tirana