37 research outputs found

    Homogeneous tuples of operators and holomorphic discrete series representation of some classical groups

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    Let T = (T1....., Tn) be a n-tuple of bounded linear operators on a fixed Hilbert space . H and let φ be a biholomorphic automorphism of Ω, the joint spectrum of T. In this paper, we consider those n-tuples T for which the joint spectrum Ω is of the form G/K, a bounded symmetric domain. Let φ be any biholornorphic automorphism of the domain Ω. Define, phi(T) via a suit­ able functional calculus and call a n-tuple of operators T homogeneous if φ(T) .is simultaneously unitarily equivalent to T for every automorphism φ of Ω. For each homogeneous operator T, let Uφ be a unitary] operator implimenting this equivalence. We obtain a characterisation of all the homogeneous operators Cowen-Douglas class and show that it is possible to choose the unitary Uφ in such a way that the map φ→ Uφ -1 is a unitary representation of the group of of biholomorpic automorphisms of Ω

    C-terminal Tail of β-Tubulin and its Role in the Alterations of Dynein Binding Mode

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    Dynein is a cytoskeletal molecular motor protein that moves along the microtubule (MT) and transports various cellular cargos during its movement. Using standard Molecular Dynamics (MD) simulation, Principle Component Analysis (PCA), and Normal Mode Analysis (NMA) methods, this investigation studied large-scale movements and local interactions of dynein’s Microtubule Binding Domain (MTBD) when bound to tubulin heterodimer subunits. Examination of the interactions between the MTBD segments, and their adjustments in terms of intra- and intermolecular distances at the interfacial area with tubulin heterodimer, particularly at α-H16, β-H18 and β-tubulin C-terminal tail (CTT), was the main focus of this study. The specific intramolecular interactions, electrostatic forces and the salt-bridge residue pairs were shown to be the dominating factors in orchestrating movements of the MTBD and MT interfacial segments in the dynein’s low-high affinity binding modes. Important interactions included β-Glu447 and β-Glu449 (CTT) with Arg3469 (MTBD-H6), Lys3472 (MTBD-H6-H7 loop) and Lys3479 (MTBD-H7); β-Glu449 with Lys3384 (MTBD-H8), Lys3386 and His3387 (MTBD-H1). The structural and precise position, orientation, and functional effects of the CTTs on the MT-MTBD, within reasonable cut-off distance for non-bonding interactions and under physiological conditions, are unavailable from the previous studies. The absence of the residues in the highly flexible MT-CTTs in the experimentally solved structures is perhaps in some cases due to insufficient data from density maps, but these segments are crucial in protein binding. The presented work contributes to the information useful for the MT-MTBD structure refinement

    A sight record of Rhesus Macaque <i>Macaca mulatta</i> (Primates: Cercopithecidae) in Karnataka, India

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    The Rhesus Macaque Macaca mulatta is one of the most widely distributed macaques belonging to the order Primates. It is found in northern, central and northeastern India as well as Central and South East Asia. However, there has been no record of this species being found in the state of Karnataka, India. This note presents the first sight record of this species in Karnataka, India

    Occurrence of philometra lateolabracis (philometridae) in the subcutaneous caudal fin region of sciaenid fishes of Bay of Bengal Large Marine Ecosystem (BOBLME), Tamil Nadu (India)

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    Present study consists the prevalence of philometrid nematode, Philometra lateolabracis infections in two species of Sciaenid fishes along the Madras coastal water, Bay of Bengal during December, 2008 to July, 2012. Out of total 295 sciaenid fishes, examined, Otolithes ruber and Pennahia macrophthalmus showed 70% & 32.5% of parasitic prevalence on the subcutaneous region on caudal fins. The number of parasitic worms per fish varied from 1 to 7 with an average of 3.18±1.64. Parasites length varies from 5-16 mm with an average of 11.18±4.62 mm. The minimum and maximum sizes and weight of Sciaenid fishes were caught from Kasimedu landing centre (Chennai) during October-December, 2012 varied from180-287 mm and weight 120-245 gm respectively

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    Not AvailablePresent study consists the prevalence of philometrid nematode, Philometra lateolabracis infections in two species of Sciaenid fishes along the Madras coastal water, Bay of Bengal during December, 2008 to July, 2012. Out of total 295 sciaenid fishes, examined, Otolithes ruber and Pennahia macrophthalmus showed 70% & 32.5% of parasitic prevalence on the subcutaneous region on caudal fins. The number of parasitic worms per fish varied from 1 to 7 with an average of 3.18±1.64. Parasites length varies from 5-16 mm with an average of 11.18±4.62 mm. The minimum and maximum sizes and weight of Sciaenid fishes were caught from Kasimedu landing centre (Chennai) during October-December, 2012 varied from180-287 mm and weight 120-245 gm respectively.Not Availabl

    Book review

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