12 research outputs found
Radical Reaction of Sodium Hypophosphite with Terminal Alkynes: Synthesis of 1, 1-Bis-H-phosphinates
Synthesis of phosphinate analogues of the phospholipid anti-tumour agent hexadecylphosphocholine (miltefosine)
Asymptomatic and symptomatic embolic events in infective endocarditis: associated factors and clinical impact
Recent Progress in Transition Metal-Catalyzed Addition Reactions of H–P(O) Compounds with Unsaturated Carbon Linkages
Allylic Phosphinates via Palladium-Catalyzed Allylation of H-Phosphinic Acids with Allylic Alcohols
Triethylborane-Initiated Room Temperature Radical Addition of Hypophosphites to Olefins: Synthesis of Monosubstituted Phosphinic Acids and Esters
A Highly Regioselective Palladium-Catalyzed Hydrophosphination of Alkynes Using a Diphosphine−Hydrosilane Binary System
Recent Advances in Synthesis of P-BH3 Compounds
International audienceThis chapter is dedicated to the main achievements since 2007 regarding the synthesis of BH3-phosphorus complexes. Among this class of compounds, phosphine-boranes are the most studied derivatives, mainly as valuable surrogates of phosphines, enabling easy handling and purification. Contrarily, metal phosphido-boranes were so far only considered as in situ intermediates in the P-functionalization of secondary phosphine-boranes. Thorough investigations of their structures as well as their chemical properties have been recently reported. Besides, phosphine-boranes and their phosphides, new families of phosphorus-BH3 complexes, have emerged as useful precursors of new structures in the asymmetric series. New routes toward optically active phosphinous-acid boranes and their esters were developed and applied to the synthesis of enantiopure P-stereogenic secondary and tertiary phosphine-boranes. The stereoselective synthesis of P-stereogenic aminophosphine-boranes, precursors of a new class of chiral ligands has been shortly reported. Studies dealing with the synthesis and reactivity of phosphonite-boranes were successfully applied to the development of efficient syntheses of functionalized H-phosphinates, compounds difficult to access by other routes