New Partition Identities From Cℓ(1)C_{\ell}^{(1)}-Modules

In this paper we conjecture combinatorial Rogers-Ramanujan type colored partition identities related to standard representations of the affine Lie algebra of type $C^{(1)}_\ell$, $\ell\geq2$, and we conjecture similar colored partition identities with no obvious connection to representation theory of affine Lie algebras.Comment: 19 page

Some partition and analytical identities arising from the Alladi, Andrews, Gordon bijection

In the work of Alladi et al. (J Algebra 174:636–658, 1995) the authors provided a generalization of the two Capparelli identities involving certain classes of integer partitions. Inspired by that contribution, in particular as regards the general setting and the tools the authors employed, we obtain new partition identities by identifying further sets of partitions that can be explicitly put into a one-to-one correspondence by the method described in the 1995 paper. As a further result, although of a different nature, we obtain an analytical identity of Rogers–Ramanujan type, involving generating functions, for a class of partition identities already found in that paper and that generalize the first Capparelli identity and include it as a particular case. To achieve this, we apply the same strategy as Kanade and Russell did in a recent paper. This method relies on the use of jagged partitions that can be seen as a more general kind of integer partitions

SMaRT lncRNA controls translation of a G-quadruplex-containing mRNA antagonizing the DHX36 helicase

Guanine-quadruplexes (G4) included in RNA molecules exert several functions in controlling gene expression at post-transcriptional level; however, the molecular mechanisms of G4-mediated regulation are still poorly understood. Here, we describe a regulatory circuitry operating in the early phases of murine muscle differentiation in which a long non-coding RNA (SMaRT) base pairs with a G4-containing mRNA (Mlx-γ) and represses its translation by counteracting the activity of the DHX36 RNA helicase. The time-restricted, specific effect of lnc-SMaRT on the translation of Mlx-γ isoform modulates the general subcellular localization of total MLX proteins, impacting on their transcriptional output and promoting proper myogenesis and mature myotube formation. Therefore, the circuitry made of lnc-SMaRT, Mlx-γ, and DHX36 not only plays an important role in the control of myogenesis but also unravels a molecular mechanism where G4 structures and G4 unwinding activities are regulated in living cells

Big data managing in a landslide early warning system: Experience from a ground-based interferometric radar application

A big challenge in terms or landslide risk mitigation is represented by increasing the resiliency of society exposed to the risk. Among the possible strategies with which to reach this goal, there is the implementation of early warning systems. This paper describes a procedure to improve early warning activities in areas affected by high landslide risk, such as those classified as critical infrastructures for their central role in society. This research is part of the project LEWIS (Landslides Early Warning Integrated System): An Integrated System for Landslide Monitoring, Early Warning and Risk Mitigation along Lifelines. LEWIS is composed of a susceptibility assessment methodology providing information for single points and areal monitoring systems, a data transmission network and a data collecting and processing center (DCPC), where readings from all monitoring systems and mathematical models converge and which sets the basis for warning and intervention activities. The aim of this paper is to show how logistic issues linked to advanced monitoring techniques, such as big data transfer and storing, can be dealt with compatibly with an early warning system. Therefore, we focus on the interaction between an areal monitoring tool (a ground-based interferometric radar) and the DCPC. By converting complex data into ASCII strings and through appropriate data cropping and average, and by implementing an algorithm for line-of-sight correction, we managed to reduce the data daily output without compromising the capability for performing

Continuum emission enhancements and penumbral changes observed during flares by IRIS, ROSA, and Hinode

In this paper we describe observations acquired by satellite instruments (Hinode/SOT and IRIS) and ground-based telescopes (ROSA@DST) during two consecutive C7.0 and X1.6 flares occurred in active region NOAA 12205 on 2014 November 7. The analysis of these data show the presence of continuum enhancements during the evolution of the events, observed both in ROSA images and in IRIS spectra. Moreover, we analyze the role played by the evolution of the δ sunspots of the active region in the flare triggering, indicating the disappearance of a large portion of penumbra around these sunspots

RANKL Inhibition Through Osteoprotegerin Blocks Bone Loss in Experimental Periodontitis

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141376/1/jper1300.pd

A Method for Generation Phage Cocktail with Great Therapeutic Potential

Background: Bacteriophage could be an alternative to conventional antibiotic therapy against multidrug-resistant bacteria. However, the emergence of resistant variants after phage treatment limited its therapeutic application. Methodology/Principal Findings: In this study, an approach, named ‘‘Step-by-Step’ ’ (SBS), has been established. This method takes advantage of the occurrence of phage-resistant bacteria variants and ensures that phages lytic for wild-type strain and its phage-resistant variants are selected. A phage cocktail lytic for Klebsiella pneumoniae was established by the SBS method. This phage cocktail consisted of three phages (GH-K1, GH-K2 and GH-K3) which have different but overlapping host strains. Several phage-resistant variants of Klebsiella pneumoniae were isolated after different phages treatments. The virulence of these variants was much weaker [minimal lethal doses (MLD).1.3610 9 cfu/mouse] than that of wild-type K7 countpart (MLD = 2.5610 3 cfu/mouse). Compared with any single phage, the phage cocktail significantly reduced the mutation frequency of Klebsiella pneumoniae and effectively rescued Klebsiella pneumoniae bacteremia in a murine K7 strain challenge model. The minimal protective dose (MPD) of the phage cocktail which was sufficient to protect bacteremic mice from lethal K7 infection was only 3.0610 4 pfu, significantly smaller (p,0.01) than that of single monophage. Moreover, a delayed administration of this phage cocktail was still effective in protection against K7 challenge. Conclusions/Significance: Our data showed that the phage cocktail was more effective in reducing bacterial mutatio