61 research outputs found

    New Experimental limit on Optical Photon Coupling to Neutral, Scalar Bosons

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    We report on the first results of a sensitive search for scalar coupling of photons to a light neutral boson in the mass range of approximately 1.0 milli-electron volts and coupling strength greater than 106^-6 GeV1^-1 using optical photons. This was a photon regeneration experiment using the "light shining through a wall" technique in which laser light was passed through a strong magnetic field upstream of an optical beam dump; regenerated laser light was then searched for downstream of a second magnetic field region optically shielded from the former. Our results show no evidence for scalar coupling in this region of parameter space.Comment: pdf-file, 10 pages, 4 figures, submitted to Physical Review Letter

    Axion Searches with Helioscopes and astrophysical signatures for axion(-like) particles

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    The first part reviews the working mechanisms, capabilities and performance of axion helioscopes, including the achieved results so far. The 2nd part is observationally driven. New simulation results obtained with the Geant4 code reconstruct spectral shape of solar X-ray spectra, and their isotropic emission and lateral size. The derived rst mass of the axion(-like) particles is ~10meV. The axion interaction with magnetic field gradient is a generic theoretical suggestion that could reconcile present limits with relevant solar X-ray activity. A short outlook of the experimentally expanding solar axion field is given.Comment: 31 pages, 18 figures. Aded 1 author, updated references. Accepted for the special issue of NJP on dark matter (July 2009

    First lasing of the Jefferson Lab IR Demo FEL

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    As reported previously [1], Jefferson Lab is building a free-electron laser capable of generating a continuous wave kilowatt laser beam. The driver-accelerator consists of a superconducting, energy-recovery accelerator. The initial stage of the program was to produce over 100 W of average power with no recirculation. In order to provide maximum gain the initial wavelength was chosen to be 5 mu-m and the initial beam energy was chosen to be 38.5 MeV. On June 17, 1998, the laser produced 155 Watts cw power at the laser output with a 98% reflective output coupler. On July 28th, 311 Watts cw power was obtained using a 90% reflective output coupler. A summary of the commissioning activities to date as well as some novel lasing results will be summarized in this paper. Present work is concentrated on optimizing lasing at 5 mu-m, obtaining lasing at 3 mu-m, and commissioning the recirculation transport in preparation for kilowatt lasing this fall

    The epithelial cholinergic system of the airways

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    Acetylcholine (ACh), a classical transmitter of parasympathetic nerve fibres in the airways, is also synthesized by a large number of non-neuronal cells, including airway surface epithelial cells. Strongest expression of cholinergic traits is observed in neuroendocrine and brush cells but other epithelial cell types—ciliated, basal and secretory—are cholinergic as well. There is cell type-specific expression of the molecular pathways of ACh release, including both the vesicular storage and exocytotic release known from neurons, and transmembrane release from the cytosol via organic cation transporters. The subcellular distribution of the ACh release machineries suggests luminal release from ciliated and secretory cells, and basolateral release from neuroendocrine cells. The scenario as known so far strongly suggests a local auto-/paracrine role of epithelial ACh in regulating various aspects on the innate mucosal defence mechanisms, including mucociliary clearance, regulation of macrophage function and modulation of sensory nerve fibre activity. The proliferative effects of ACh gain importance in recently identified ACh receptor disorders conferring susceptibility to lung cancer. The cell type-specific molecular diversity of the epithelial ACh synthesis and release machinery implies that it is differently regulated than neuronal ACh release and can be specifically targeted by appropriate drugs
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