A Complete review on Detection, Prevention and Treatment of Pyorrhea a major problem in old age people

 Pyorrhea an infectious diseases that can be damage the gums and destroys the jaw bones. Pyorrhea is mainly seen in people over 35 years of age that causes tooth loss over time. The current study is clear that gingival bleeding and visible inflammation are the first signs of gingivitis. Continuous bleeding gums could be caused by plaque formation on the teeth, which is connected to a number of systemic disorders in older persons with periodontal diseases. The most common causes of bleeding gum include roughly brushing or wearing fake teeth that do not fit properly and formation of plaque at the gum line, which leads to inflammation. A clinical trial was performed in order to evaluate the effectiveness of mouth wash with Promegranate and Chamomile plant extract, against Chlorhexidine 0.12% in the gingiva bleeding condition. Other treatment is give the prescription of vitamin supplement for bleeding gum. It can be an indication loe ,parfit and Massler depend on a decision about oral color, texture, and contour to determine the level of inflammation in the gums. The aim of this review is to examine the gingival response to dental plaque in gingivitis patients without gum damage, with either a low or high bleeding or plaque ratio. The aim of this article is to aware people to not take this disease lightly and to take proper treatment

The Overall Effects Of Covid-19 On The Basis Of Management And Treatment In Pediatric Patients: A Complete Review

COVID-19 is a disease that is caused by a novel coronavirus known as SARS-COV-2 that has been spreading around the world. Controlling COVID-19 is more difficult due to the highly infectious nature of the disease and clinical complications in patients. Everyone worldwide has struggled with it since it was first introduced in Wuhan, in the Chinese state of Hubei. It reaches every corner, infecting individuals from any walk of life. Everybody has been affected in some way, with the majority usually negatively. Fortunately, they have not yet experienced the direct health effects of COVID-19, but this emergency has had a major effect on their overall health. The viral infection may stay in the atmosphere for a long time, and it mostly spreads through the air. It affects the mucous membranes of the mouth, nose, and eyes. Children’s health, social, and financial well-being are all negatively impacted by the COVID-19 epidemic, with the poorest children, such as those who are homeless and those who are detained, being most negatively impacted. School closings, social isolation, and loneliness enhance children’s risk of nutritional deficiency, increase their exposure to domestic abuse, build their level of anxiety and stress, and decrease their access to essential family and child care services. According to research, the virus is continually changing and spreading through asymptomatic carriers, which indicates a serious threat to global health. This paper provides an overview of the most recent data on the overall effects of COVID-19 on the basis of management and treatment in pediatric patients

Sequential extraction of proanthocyanidin fractions from Ficus species and their effects on rumen enzyme activities in vitro

Three proanthocyanidin fractions per species were sequentially extracted by 50% (v/v) methanol–water, 70% (v/v) acetone–water, and distilled water from leaves of Ficus racemosa (fractions FR) and F. religiosa (fractions FRL) to yield fractions FR-50, FR-70, FR-DW, FRL-50, FRL-70, and FRL-DW. Fractions were examined for their molecular structure, effect on ruminal enzyme activities, and principal leaf protein (Rubisco) solubilization in vitro. All fractions except FRL-70 contained flavonoids including (+) catechin, (−) epicatechin, (+) gallocatechin, (−) epigallocatechin, and their -4-phloroglucinol adducts. The fractions FRL-50 and FRL-DW significantly (p < 0.05) inhibited the activity of ruminal glutamic oxaloacetic transaminase and glutamic pyruvic transaminase. All fractions inhibited glutamate dehydrogenase activity (p < 0.05) with increasing concentration, while protease activity decreased 15–18% with increasing concentrations. Fractions FRL-50 and FRL-DW completely inhibited the activity of cellulase enzymes. Solubilization of Rubisco was higher in F. religiosa (22.36 ± 1.24%) and F. racemosa (17.26 ± 0.61%) than that of wheat straw (WS) (8.95 ± 0.95%) and berseem hay (BH) (3.04 ± 0.08%). A significant (p < 0.05) increase in protein solubilization was observed when WS and BH were supplemented with FR and FRL leaves at different proportions. The efficiency of microbial protein was significantly (p < 0.05) greater in diets consisting of WS and BH with supplementation of F. racemosa leaves in comparison to those supplemented with F. religiosa leaves. The overall conclusion is that the fractions extracted from F. religiosa showed greater inhibitory effects on rumen enzymes and recorded higher protein solubilization in comparison to the F. racemosa. Thus, PAs from F. religiosa are potential candidates to manipulate rumen enzymes activities for efficient utilization of protein and fiber in ruminants

Proanthocyanidins modulate rumen enzyme activities and protein utilization In Vitro

This study investigated the principal leaf protein (rubisco) solubilization and in vitro ruminal enzyme activity in relation to the molecular structure of proanthocyanidins extracted from leaves of Anogeissus pendula and Eugenia jambolana. Six proanthocyanidin fractions were extracted by 50% (v/v) methanol–water followed by 70% (v/v) acetone–water and then distilled water from leaves of A. pendula (AP) and E. jambolana (EJ) to yield EJ–70, EJ–50, EJ–DW, AP–70, AP–50 and AP–DW. Fractions were examined for their molecular structure and their effects on sheep ruminal enzymes and solubilization of rubisco in vitro. All fractions significantly (p < 0.05) inhibited the activity of ruminal glutamic oxaloacetic transaminase and glutamic pyruvic transaminase. The fractions AP–50 and EJ–50 significantly inhibited the activity of the R-cellulase enzyme. Most of the fractions inhibited R-glutamate dehydrogenase activity (p < 0.05) by increasing its concentration, while protease activity decreased by up to 58% with increasing incubation time and concentration. The solubilization of rubisco was observed to be comparatively higher in A. pendula (16.60 ± 1.97%) and E. jambolana (15.03 ± 1.06%) than that of wheat straw (8.95 ± 0.95%) and berseem hay (3.04 ± 0.08%). A significant (p < 0.05) increase in protein solubilization was observed when wheat straw and berseem hay were supplemented with A. pendula and E. jambolana leaves at different proportions. The efficiency of microbial protein was significantly (p < 0.05) greater with the supplementation of leaves of A. pendula in comparison to E. jambolana. The overall conclusion is that the proanthocyanidins obtained from E. jambolana exhibited greater inhibitory activities on rumen enzymes, whereas A. pendula recorded higher protein solubilization. Thus, PAs from A. pendula and E. jambolana appear to have the potential to manipulate rumen enzyme activities for efficient utilization of protein and fiber in ruminants

A novel anomaly behavior detection scheme for mobile ad hoc networks

To sustain the security services in a Mobile Ad Hoc Networks (MANET), applications in terms of confidentially, authentication, integrity, authorization, key management, and abnormal behavior detection/anomaly detection are significant. The implementation of a sophisticated security mechanism requires a large number of network resources that degrade network performance. In addition, routing protocols designed for MANETs should be energy efficient in order to maximize network performance. In line with this view, this work proposes a new hybrid method called the data-driven zone-based routing protocol (DD-ZRP) for resource-constrained MANETs that incorporate anomaly detection schemes for security and energy awareness using Network Simulator 3. Most of the existing schemes use constant threshold values, which leads to false positive issues in the network. DD-ZRP uses a dynamic threshold to detect anomalies in MANETs. The simulation results show an improved detection ratio and performance for DD-ZRP over existing schemes; the method is substantially better than the prevailing protocols with respect to anomaly detection for security enhancement, energy efficiency, and optimization of available resources

Measurement and modeling of soil water regime in a lowland paddy field showing preferential transport

Paddy is commonly grown under flooded or submerged condition in which substantial amount of water is lost by different processes. Puddling is traditionally done to reduce water loss from lowland rice fields. Since the very step of puddling, rice root zone undergoes structural changes leading to the formation of a layered profile having a hydraulically less-conductive plow sole below the root zone. However, studies have shown that soil cracking and the presence of preferential flow paths in puddle fields defeat this purpose. Description of soil water regime in such a dynamic soil requires an in situ measurement method for soil hydraulic properties. A field experiment was conducted in twelve 30 m2 plots during the rainy seasons (June to October) of 2004 and 2005 to evaluate a suitable method for estimating soil hydraulic properties of lowland paddy soil. Results showed that piezometric (pressure) heads installed in different soil layers responded to the drying and wetting cycles typically followed in transplanted rice and are observed as a part of monsoon climate in eastern India. The Marquardt-Levenberg algorithm built in the HYDRUS-1D simulation environment was used to inversely estimate soil hydraulic parameters. Estimated parameters revealed larger hydraulic conductivity for the compacted plow sole than those published in literature, which may have resulted from alternate wetting and drying typically observed under monsoon climate and earthworm burrows observed in our experimental field. Results from simulation studies suggest that both the single- and dual-porosity models could simulate water flow considerably well in lowland paddy field although the latter described pressure head time series data slightly better in about 50% of simulations. Similar performance of the single- vs. dual-porosity model may have resulted from estimating a seasonally mean soil hydraulic properties which include the effect of both preferential flow and matrix flow as the specific soil and boundary conditions prevailed. While water may have preferentially transported through the macropores during the wetting cycles in a near-saturated soil, it would have dominantly moved through soil matrix during the drying cycles. This study shows that simple piezometers may be combined with a simulation model to estimate hydraulic properties of different soil layers in a lowland paddy field