Dispersion analysis techniques within the space vehicle dynamics simulation program

The Space Vehicle Dynamics Simulation (SVDS) program was evaluated as a dispersion analysis tool. The Linear Error Analysis (LEA) post processor was examined in detail and simulation techniques relative to conducting a dispersion analysis using the SVDS were considered. The LEA processor is a tool for correlating trajectory dispersion data developed by simulating 3 sigma uncertainties as single error source cases. The processor combines trajectory and performance deviations by a root-sum-square (RSS process) and develops a covariance matrix for the deviations. Results are used in dispersion analyses for the baseline reference and orbiter flight test missions. As a part of this study, LEA results were verified as follows: (A) Hand calculating the RSS data and the elements of the covariance matrix for comparison with the LEA processor computed data. (B) Comparing results with previous error analyses. The LEA comparisons and verification are made at main engine cutoff (MECO)

New Insights on Interstellar Gas-Phase Iron

In this paper, we report on the gas-phase abundance of singly-ionized iron (Fe II) for 51 lines of sight, using data from the Far Ultraviolet Spectroscopic Explorer (FUSE). Fe II column densities are derived by measuring the equivalent widths of several ultraviolet absorption lines and subsequently fitting those to a curve of growth. Our derivation of Fe II column densities and abundances creates the largest sample of iron abundances in moderately- to highly-reddened lines of sight explored with FUSE, lines of sight that are on average more reddened than lines of sight in previous Copernicus studies. We present three major results. First, we observe the well-established correlation between iron depletion and and also find trends between iron depletion and other line of sight parameters (e.g. f(H_2), E_(B-V), and A_V), and examine the significance of these trends. Of note, a few of our lines of sight probe larger densities than previously explored and we do not see significantly enhanced depletion effects. Second, we present two detections of an extremely weak Fe II line at 1901.773 A in the archival STIS spectra of two lines of sight (HD 24534 and HD 93222). We compare these detections to the column densities derived through FUSE spectra and comment on the line's f-value and utility for future studies of Fe II. Lastly, we present strong anecdotal evidence that the Fe II f-values derived empirically through FUSE data are more accurate than previous values that have been theoretically calculated, with the probable exception of f_1112.Comment: Accepted for publication in ApJ, 669, 378; see ApJ version for small updates. 53 total pages (preprint format), 7 tables, 11 figure

Asteroseismic Signatures of Stellar Magnetic Activity Cycles

Observations of stellar activity cycles provide an opportunity to study magnetic dynamos under many different physical conditions. Space-based asteroseismology missions will soon yield useful constraints on the interior conditions that nurture such magnetic cycles, and will be sensitive enough to detect shifts in the oscillation frequencies due to the magnetic variations. We derive a method for predicting these shifts from changes in the Mg II activity index by scaling from solar data. We demonstrate this technique on the solar-type subgiant beta Hyi, using archival International Ultraviolet Explorer spectra and two epochs of ground-based asteroseismic observations. We find qualitative evidence of the expected frequency shifts and predict the optimal timing for future asteroseismic observations of this star.Comment: 5 pages including 3 figures and 1 table, MNRAS Letters accepte

Precision determination of absolute neutron flux

A technique for establishing the total neutron rate of a highly-collimated monochromatic cold neutron beam was demonstrated using a method of an alpha-gamma counter. The method involves only the counting of measured rates and is independent of neutron cross sections, decay chain branching ratios, and neutron beam energy. For the measurement, a target of 10B-enriched boron carbide totally absorbed the neutrons in a monochromatic beam, and the rate of absorbed neutrons was determined by counting 478keV gamma rays from neutron capture on 10B with calibrated high-purity germanium detectors. A second measurement based on Bragg diffraction from a perfect silicon crystal was performed to determine the mean de Broglie wavelength of the beam to a precision of 0.024 %. With these measurements, the detection efficiency of a neutron monitor based on neutron absorption on 6Li was determined to an overall uncertainty of 0.058 %. We discuss the principle of the alpha-gamma method and present details of how the measurement was performed including the systematic effects. We also describe how this method may be used for applications in neutron dosimetry and metrology, fundamental neutron physics, and neutron cross section measurements.Comment: 44 page

The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease

Tissue engineering is a pioneering field with huge advances in recent times. These advances are not only in the understanding of how cells can be manipulated but also in potential clinical applications. Thus, tissue engineering, when applied to skeletal muscle cells, is an area of huge prospective benefit to patients with muscle disease/damage. This could include damage to muscle from trauma and include genetic abnormalities, for example, muscular dystrophies. Much of this research thus far has been focused on satellite cells, however, mesenchymal stem cells have more recently come to the fore. In particular, results of trials and further research into their use in heart failure, stress incontinence, and muscular dystrophies are eagerly awaited. Although no doubt, stem cells will have much to offer in the future, the results of further research still limit their use

Tendon Regeneration and Repair with Stem Cells

The use of stems cells in tendon repair is of particular interest given the frequency of tendon injuries worldwide together with the technical difficulty often encountered when repairing or augmenting tendons. Stems cells have the capability to differentiate into a variety of different cell types including osteocytes and tenocytes, and if normal architecture of damaged tendon (either macroscopic or microscopic) could be restored, this would significantly improve the management of patients with these injuries. There is already encouraging research on the use of stems cells clinically although considerable further work is required to improve knowledge and clinical applications of stem cells in tissue engineering

ICONA: Inter Cluster ONOS Network Application

Several Network Operating Systems (NOS) have been proposed in the last few years for Software Defined Networks; however, a few of them are currently offering the resiliency, scalability and high availability required for production environments. Open Networking Operating System (ONOS) is an open source NOS, designed to be reliable and to scale up to thousands of managed devices. It supports multiple concurrent instances (a cluster of controllers) with distributed data stores. A tight requirement of ONOS is that all instances must be close enough to have negligible communication delays, which means they are typically installed within a single datacenter or a LAN network. However in certain wide area network scenarios, this constraint may limit the speed of responsiveness of the controller toward network events like failures or congested links, an important requirement from the point of view of a Service Provider. This paper presents ICONA, a tool developed on top of ONOS and designed in order to extend ONOS capability in network scenarios where there are stringent requirements in term of control plane responsiveness. In particular the paper describes the architecture behind ICONA and provides some initial evaluation obtained on a preliminary version of the tool.Comment: Paper submitted to a conferenc