94 research outputs found

    En defensa de una teoria cognitiva de las emociones: el caso de la inercia emocional

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    Durante los últimos años, las emociones volvieron a ser un tópico de interés para disciplinas como la filosofía y la psicología, principalmente por el cuestionamiento a la tradicional oposición entre emoción y razón (Greenspan, 2004). A partir de este cuestionamiento se pusieron de relieve distintas concepciones acerca de la naturaleza y la función de las emociones humanas

    Debates filosóficos en torno a enfoques teóricos y empíricos de la psicología actual

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    El presente simposio se propone explorar a través de tres presentaciones algunos debates filosóficos relevantes en el seno de la Psicología actual. El objetivo es analizar ciertos desafíos conceptuales, epistemológicos y metodológicos que revisten distintos enfoques teóricos y empíricos contemporáneos, particularmente en problemas de interfase entre la Psicología Cognitiva, las Neurociencias Cognitivas, la Psicología Social y la Psicopatología. El primer trabajo (M. Fissore), en el marco de las Neurociencias Cognitivas, explorará las distintas perspectivas teóricas en torno al concepto de "reutilización neuronal" para las funciones cognitivas, a fin de dilucidar los supuestos centrales de dichas perspectivas, en contraste con los enfoques clásicos sobre la arquitectura funcional del cerebro. El segundo trabajo (Z. Sánchez), en el marco del problema de la Psicología Cognitiva y Social sobre cómo atribuimos estados mentales a otros agentes, recuperará el debate sobre la riqueza de la experiencia perceptiva a partir de un análisis de los alcances y límites de la tesis de la "percepción social directa", así como también se vinculará este debate con la hipótesis del aprendizaje perceptual. Finalmente, el tercer trabajo (E. Vilatta), analizará distintos problemas epistemológicos en el seno de la Psicopatología en torno a la conceptualización y explicación de los delirios, revisando los principales punto de controversia en torno a las teorías actuales para finalmente sugerir algunas consideraciones sobre los factores que deberían considerarse para una explicación clínica y teóricamente ajustada del fenómeno.Fil: Vilatta, Emilia. Universidad Nacional de Córdoba. Facultad de Psicología. Cátedra Problemas Epistemológicos de la Psicología. Grupo de investigación Intencionalidad; Argentina.Fil: Sánchez, Zoé. Universidad Nacional de Córdoba. Facultad de Psicología. Cátedra Problemas Epistemológicos de la Psicología. Grupo de investigación Intencionalidad; Argentina.Fil: Fissore, María. Universidad Nacional de Córdoba. Facultad de Psicología. Cátedra Problemas Epistemológicos de la Psicología. Grupo de investigación Intencionalidad; Argentina

    La contabilidad socioambiental: un método para analizar las implicaciones sociales y ambientales de las organizaciones

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    This systematic review article includes the meta-analysis of scientific production of the last five years of environmental accounting reports. The objective is to publicize the environmental accounting that companies report and the impact that the industry has on the communities; in addition, the environmental cost and the appropriate use of natural resources that contributes to its quantification in accounting terms. In this study, the Prisma methodology was applied, through the systematization of the available bibliography, which allowed selecting, evaluating, and summarizing said information. 1,102 indexed articles were filtered, of which 20 articles and 8 books were selected. The result of the analysis allowed to group the concepts of environmental and social accounting, as well as to understand the implications of the socio-environmental responsibility approach for the development of the principles of sustainable development; In addition, the position of creating shared value. It is concluded that socio-environmental accounting seeks to merge private interests with social and environmental issues; to such an extent that organizations can be evaluated by their economic position and their social exercise.Este artículo de revisión sistemática incluye el metaanálisis de producción científica de los últimos cinco años de los reportes de contabilidad ambiental. El objetivo es dar a conocer la contabilidad ambiental que reportan las empresas y el impacto que tiene la industria en las comunidades; además, el costo ambiental y el uso adecuado de los recursos naturales que aporta a su cuantificación en términos contables. En este estudio se aplicó la metodología Prisma, mediante la sistematización de la bibliografía disponible, lo cual permitió seleccionar, evaluar y resumir dicha información. Se filtraron 1.102 artículos indexados, de los cuales se seleccionaron 20 artículos y 8 libros. El resultado del análisis permitió agrupar los conceptos de contabilidad ambiental y social, así como comprender las implicaciones del enfoque de la responsabilidad socioambiental para el desarrollo de los principios de desarrollo sostenible; además, la postura de la creación de valor compartido. Se concluye que la contabilidad socioambiental busca que los intereses particulares se fusionen con los asuntos sociales y ambientales; a tal punto, que las organizaciones se puedan evaluar por su postura económica y su ejercicio social

    Historical RNA expression profiles from the extinct Tasmanian tiger

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    Paleogenomics continues to yield valuable insights into the evolution, population dynamics, and ecology of our ancestors and other extinct species. However, DNA sequencing cannot reveal tissue-specific gene expression, cellular identity, or gene regulation, which are only attainable at the transcriptional level. Pioneering studies have shown that useful RNA can be extracted from ancient specimens preserved in permafrost and historical skins from extant canids, but no attempts have been made so far on extinct species. We extract, sequence, and analyze historical RNA from muscle and skin tissue of a ∼130-year-old Tasmanian tiger (Thylacinus cynocephalus) preserved in desiccation at room temperature in a museum collection. The transcriptional profiles closely resemble those of extant species, revealing specific anatomical features such as slow muscle fibers or blood infiltration. Metatranscriptomic analysis, RNA damage, tissue-specific RNA profiles, and expression hotspots genome-wide further confirm the thylacine origin of the sequences. RNA sequences are used to improve proteincoding and noncoding annotations, evidencing missing exonic loci and the location of ribosomal RNA genes while increasing the number of annotated thylacine microRNAs from 62 to 325. We discover a thylacine-specific microRNA isoform that could not have been confirmed without RNA evidence. Finally, we detect traces of RNA viruses, suggesting the possibility of profiling viral evolution. Our results represent the first successful attempt to obtain transcriptional profiles from an extinct animal species, providing thought-to-be-lost information on gene expression dynamics. These findings hold promising implications for the study of RNA molecules across the vast collections of natural history museums and from well-preserved permafrost remains

    Expansion of the SOS regulon of Vibrio cholerae through extensive transcriptome analysis and experimental validation

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    The SOS response is an almost ubiquitous response of cells to genotoxic stresses. The full complement of genes in the SOS regulon for Vibrio species has only been addressed through bioinformatic analyses predicting LexA binding box consensus and in vitro validation. Here, we perform whole transcriptome sequencing from Vibrio cholerae treated with mitomycin C as an SOS inducer to characterize the SOS regulon and other pathways affected by this treatment. Comprehensive transcriptional profiling allowed us to define the full landscape of promoters and transcripts active in V. cholerae. We performed extensive transcription start site (TSS) mapping as well as detection/quantification of the coding and non-coding RNA (ncRNA) repertoire in strain N16961. To improve TSS detection, we developed a new technique to treat RNA extracted from cells grown in various conditions. This allowed for identification of 3078 TSSs with an average 5'UTR of 116 nucleotides, and peak distribution between 16 and 64 nucleotides; as well as 629 ncRNAs. Mitomycin C treatment induced transcription of 737 genes and 28 ncRNAs at least 2 fold, while it repressed 231 genes and 17 ncRNAs. Data analysis revealed that in addition to the core genes known to integrate the SOS regulon, several metabolic pathways were induced. This study allowed for expansion of the Vibrio SOS regulon, as twelve genes (ubiEJB, tatABC, smpA, cep, VC0091, VC1190, VC1369-1370) were found to be co-induced with their adjacent canonical SOS regulon gene(s), through transcriptional read-through. Characterization of UV and mitomycin C susceptibility for mutants of these newly identified SOS regulon genes and other highly induced genes and ncRNAs confirmed their role in DNA damage rescue and protection. We show that genotoxic stress induces a pervasive transcriptional response, affecting almost 20% of the V. cholerae genes. We also demonstrate that the SOS regulon is larger than previously known, and its syntenic organization is conserved among Vibrio species. Furthermore, this specific co-localization is found in other γ-proteobacteria for genes recN-smpA and rmuC-tatABC, suggesting SOS regulon conservation in this phylum. Finally, we comment on the limitations of widespread NGS approaches for identification of all RNA species in bacteria

    Event-by-event reconstruction of the shower maximum XmaxX_{\mathrm{max}} with the Surface Detector of the Pierre Auger Observatory using deep learning

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    Reconstruction of Events Recorded with the Water-Cherenkov and Scintillator Surface Detectors of the Pierre Auger Observatory

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    Status and performance of the underground muon detector of the Pierre Auger Observatory

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    The XY Scanner - A Versatile Method of the Absolute End-to-End Calibration of Fluorescence Detectors

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    First results from the AugerPrime Radio Detector

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