2,571 research outputs found
Histone Deacetylase, Proteasome, and Heat Shock Protein Inhibitors for the Treatment of Lung Cancer
Socio-economic factors on Individual Behaviour of Mutual fund in Chennai City, India: Evidence from Juvenile age group
Juvenile age group face new and daunting economic challenges that stem from a number of sources including the financial market breakdown, outburst of the housing bubble, and the rapidly changing demographics of the nation. Using survey data, this study reveals that gender, income, knowledge, and experience emerge as important personal and social influences on juvenile age group investing behaviors in mutual funds. This underscores the importance of financial socialization of juvenile age group at school and home. In an economic downturn that demands individual responsibility and self sufficiency, wealth management is an essential component of a successful adult life. Given the importance of financial well-being, understanding these influences and contributing factors in investing behaviors in mutual funds may pay off significantly for juvenile age group’ financial future. Keywords: Individual Behaviour, Socio-economic, Mutual fund and Chennai Cit
Phytochemical, Toxicological and Pharmacological Studies of Asiasari Radix et Rhizoma: A Review
Herba Asari and Asiasari Radix (AR) have a centuries-old history as a folk medicine in China, Korea and Japan. AR has long been used in combination with other herbs to treat cough, toothache, headache, neuralgia, aphthous stomatitis, gingivitis, chronic bronchitis, asthma and allergies. AR from three species of the genus Asarum: A. heterotropoides Fr. Schmidt var. mandshuricum (Maxim.) Kitag., A. sieboldii Miq. var. seoulense Nakai and A. sieboldii Miq are recognized as original “Asiasari Radix et Rhizoma”. These species do not contain aristolochic acids (nephrotoxins present in the Asarum species) and therefore the roots of AR are recommended for use. Asiasari Radix is rich in volatile oils, phenylpropanoids, terpenoids, flavonoids, glycosides and lignins. The reported toxicological and pharmacological activities of AR, including antifungal, antimicrobial, antilisterial, antiallergic, acarcidal, larvicidal, anti-caries, anti-inflammatory, hepatoprotective, neuroprotective, cytotoxic and anticancer activities suggest its therapeutic potentials in drug discovery.Keywords: Asarum; Asiasarum, Asiasarum heterotropoides var. mandshuricum, Asiasarum sieboldiiHerba Asari, Folk medicine, Pharmacological, Toxicologica
Waste Water Reuse: Extension Approach to Depleting Water Resources
Vellore is a district in Tamil Nadu, India consisting of mainly villages having agriculture as the chief occupation. Dug wells are the major irrigation source. Numerous tanneries also throng the area which again necessitates large quantity of water to fulfill its requirements. Long-term water level fluctuations indicate lowering of water table in Vellore. Development of ground water in the district seeks immediate attention. Establishment of a wastewater reuse program and usage of reclaimed wastewater is a significant and reliable alternative solution. This practice has found implementation in developed nations but developing countries lack in community based application. In Vellore, the industrial wastewater from tanneries is collected in CETP’s (Common Effluent Treatment Plants). In Vellore Institute of Technology (VIT, Vellore) a smaller scale wastewater treatment process is carried out using biological means. Kitchen and Bathroom wastewater is treated. (BOD: 30mg/L; COD: 250mg/L) and used mainly for watering the lawns. Such wastewater reuse to be taken up in a wider scale in the various regions to combat water shortage. Effective extension of this technique needs to be taken up for community based applications. Lowering water tables can be managed, and water for irrigation can be made available round the year through such implementations
STEROID-INDUCED ANAPHYLAXIS
Ă‚Â Ă‚Â To report a severe adverse drug reaction (ADR) due to administration of injection hydrocortisone sodium succinate and to explore the possibility of an association between injection hydrocortisone and the severe ADR. After getting ethics approval from the institution, ADR form and patient's clinical record from the Department of Cardiology, in a Private Medical College was received. In that, it was recorded as a 75-year-old male patient, a case of unstable angina with troponin T - positive, was posted for coronary angiogram developed a severe reaction to intravenous (IV) hydrocortisone 100 mg stat, given to prevent allergy to contrast dye used in the procedure. 5 minutes after drug administration, he developed sudden itching all over the body, hypotension blood pressure: 60 mmHg and swelling of lips. No other drugs had been given at that time. The patient was already on aspirin 150 mg, clopidogrel 75 mg, and atorvastatin 80 mg, and enoxaparin 40 mg. The procedure was abandoned, and the patient was given injection pheniramine maleate 45.5 mg IV, injection dopamine 10 mcg/kg/min IV. He symptomatically improved within 6 hrs. Causality analysis using the WHO scale categorizes it as probable, as anaphylaxis occurred immediately after administration of hydrocortisone, no other drugs were given at that time, and rechallenge was not done. Very few cases of various steroid-induced anaphylaxis have been reported worldwide. This one among the rare ADR report may be due to the steroid or the excipients in the preparation. Skin prick test or in vitro (radioallergosorbent test assay) test can be done immediately to confirm the causative allergen in this case and would also help in identifying specific agents that will be tolerated in the future treatment
Recoganisation and security guidance of data integrity in cloud storage
Cloud computing has been envisioned as the de-facto solution to the rising storage costs of IT Enterprises. With the high costs of data storage devices as well as the rapid rate at which data is being generated it proves costly for enterprises or individual users to frequently update their hardware. Storage outsourcing of data to cloud storage helps such firms by reducing the costs of storage, maintenance and personnel. It can also assure a reliable storage of important data by keeping multiple copies of the data thereby reducing the chance of losing data by hardware failures. The study deal with the problem of implementing a protocol for obtaining a proof of data possession in the cloud sometimes referred to as Proof of irretrievability (POR). The problem tries to obtain and verify a proof that the data that is stored by a user at remote data storage in the cloud (called cloud storage archives or simply archives) is not modified by the archive and thereby the integrity of the data is assured. The verification systems prevent the cloud storage archives from misrepresenting or modifying the data stored at it without the consent of the data owner by using frequent checks on the storage archives. 
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