Effective mass theory of monolayer \delta-doping in the high-density limit

Monolayer \delta-doped structures in silicon have attracted renewed interest with their recent incorporation into atomic-scale device fabrication strategies as source and drain electrodes and in-plane gates. Modeling the physics of \delta-doping at this scale proves challenging, however, due to the large computational overhead associated with ab initio and atomistic methods. Here, we develop an analytical theory based on an effective mass approximation. We specifically consider the Si:P materials system, and the limit of high donor density, which has been the subject of recent experiments. In this case, metallic behavior including screening tends to smooth out the local disorder potential associated with random dopant placement. While smooth potentials may be difficult to incorporate into microscopic, single-electron analyses, the problem is easily treated in the effective mass theory by means of a jellium approximation for the ionic charge. We then go beyond the analytic model, incorporating exchange and correlation effects within a simple numerical model. We argue that such an approach is appropriate for describing realistic, high-density, highly disordered devices, providing results comparable to density functional theory, but with greater intuitive appeal, and lower computational effort. We investigate valley coupling in these structures, finding that valley splitting in the low-lying \Gamma band grows much more quickly than the \Gamma-\Delta band splitting at high densities. We also find that many-body exchange and correlation corrections affect the valley splitting more strongly than they affect the band splitting

First-Order Melting of a Moving Vortex Lattice: Effects of Disorder

We study the melting of a moving vortex lattice through numerical simulations with the current driven 3D XY model with disorder. We find that there is a first-order phase transition even for large disorder when the corresponding equilibrium transition is continuous. The low temperature phase is an anisotropic moving glass.Comment: Important changes from original version. Finite size analysis of results has been added. Figure 2 has been changed. There is a new additional Figure. To be published in Physical Review Letter

Driven vortices in 3D layered superconductors: Dynamical ordering along the c-axis

We study a 3D model of driven vortices in weakly coupled layered superconductors with strong pinning. Above the critical force $F_c$, we find a plastic flow regime in which pancakes in different layers are uncoupled, corresponding to a pancake gas. At a higher $F$, there is an ``smectic flow'' regime with short-range interlayer order, corresponding to an entangled line liquid. Later, the transverse displacements freeze and vortices become correlated along the c-axis, resulting in a transverse solid. Finally, at a force $F_s$ the longitudinal displacements freeze and we find a coherent solid of rigid lines.Comment: 4 pages, 3 postscript figure

Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance

The accumulation of α-synuclein (α-syn) in intracellular formations known as Lewy bodies (LBs) is associated with several neurodegenerative diseases including Parkinson's disease and Lewy Body Dementia. There is still limited understanding of how α-syn and LB formation is associated with cellular dysfunction and degeneration in these diseases. To examine the clearance and production dynamics of α-syn we transduced organotypic murine brain slice cultures (BSCs) with recombinant adeno-associated viruses (rAAVs) to express Dendra2-tagged human wild-type (WT) and mutant A53T α-syn, with and without the addition of exogenous α-syn fibrillar seeds and tracked them over several weeks in culture using optical pulse labeling. We found that neurons expressing WT or mutant A53T human α-syn show similar rates of α-syn turnover even when insoluble, phosphorylated Ser129 α-syn has accumulated. Taken together, this data reveals α-syn aggregation and overexpression, pSer129 α-syn, nor the A53T mutation affect α-syn dynamics in this system. Prion-type seeding with exogenous α-syn fibrils significantly slows α-syn turnover, in the absence of toxicity but is associated with the accumulation of anti-p62 immunoreactivity and Thiazin Red positivity. Prion-type induction of α-syn aggregation points towards a potential protein clearance deficit in the presence of fibrillar seeds and the ease of this system to explore precise mechanisms underlying these processes. This system facilitates the exploration of α-syn protein dynamics over long-term culture periods. This platform can further be exploited to provide mechanistic insight on what drives this slowing of α-syn turnover and how therapeutics, other genes or different α-syn mutations may affect α-syn protein dynamics

Transverse depinning and melting of a moving vortex lattice in driven periodic Josephson junction arrays

We study the effect of thermal fluctuations in a vortex lattice driven in the periodic pinning of a Josephson junction array. The phase diagram current ($I$) vs. temperature ($T$) is studied. Above the critical current $I_c(T)$ we find a moving vortex lattice (MVL) with anisotropic Bragg peaks. For large currents $I\gg I_c(T)$, there is a melting transition of the MVL at $T_M(I)$. When applying a small transverse current to the MVL, there is no dissipation at low $T$. We find an onset of transverse vortex motion at a transverse depinning temperature $T_{tr}(I)<T_M(I)$.Comment: 4 pages, 4 figures, Figure 2 changed, added new reference

Dynamic transition in vortex flow in strongly disordered Josephson junction arrays and superconducting thin films

We study the dynamics of vortices in strongly disordered $d=2$ Josephson junction arrays and superconducting films driven by a current. We find a dynamic phase transition in vortex flow at a current $I_p>I_c$. Below $I_p$ there is plastic flow characterized by an average-velocity correlation length scale $\xi_v$ in the direction of motion, which diverges when approaching $I_p$. Above $I_p$ we find a moving vortex phase with homogeneous flow and short range smectic order. A finite size analysis shows that this phase becomes asymptotically a liquid for large length scales.Comment: 4 pages, 4 figure

Stronger subjects select a movement pattern that may reduce ACL loading during cutting

Davies, WT, Ryu, JH, Graham-Smith, P, Goodwin, JE, and Cleather, DJ. Stronger subjects select a movement pattern that may reduce anterior cruciate ligament loading during cutting. J Strength Cond Res 36(7): 1853–1859, 2022—Increased strength has been suggested to reduce the incidence of anterior cruciate ligament (ACL) injury as part of wider neuromuscular training programs; however, the mechanism of this is not clear. Cutting is a high-risk maneuver for ACL injury, but limited research exists as to how strength affects sagittal plane biomechanics during this movement. Sixteen subjects were split into a stronger and weaker group based on their relative peak isometric strength in a unilateral squat (stronger: 29.0 ± 3.4 N·kg−1 and weaker: 18.3 ± 4.1 N·kg−1). Subjects performed 45° cuts with maximal intent 3 times, at 3 different approach velocities (2, 4, and 6 m·s−1). Kinematics and ground reaction forces were collected using optical motion capture and a force platform. The stronger group had lower knee extensor moments, larger hip extensor moments, and a greater peak knee flexion angle than the weaker group (p < 0.05). There was a trend for greater knee flexion at initial contact in the stronger group. There were no differences in resultant ground reaction forces between groups. The stronger group relied more on the hip than the knee during cutting and reached greater knee flexion angles. This could decrease ACL loading by reducing the extensor moment required at the knee during weight acceptance. Similarly, the greater knee flexion angle during weight acceptance is likely to be protective of the ACL

Mode-locking in driven vortex lattices with transverse ac-drive and random pinning

We find mode-locking steps in simulated current-voltage characteristics of driven vortex lattices with {\it random} pinning when an applied ac-current is {\it perpendicular} to the dc-current. For low frequencies there is mode-locking only above a non-zero threshold ac force amplitude, while for large frequencies there is mode-locking for any small ac force. This is consistent with the nature of {\it transverse} temporal order in the different regimes in the absence of an applied ac-drive. For large frequencies the magnitude of the fundamental mode-locked step depends linearly with the ac force amplitude.Comment: 4 pages, 4 figures, .tar.gz fil

Mode-locking in ac-driven vortex lattices with random pinning

We find mode-locking steps in simulated current-voltage characteristics of ac-driven vortex lattices with {\it random} pinning. For low frequencies there is mode-locking above a finite ac force amplitude, while for large frequencies there is mode-locking for any small ac force. This is correlated with the nature of temporal order in the different regimes in the absence of ac drive. The mode-locked state is a frozen solid pinned in the moving reference of frame, and the depinning from the step shows plastic flow and hysteresis.Comment: 4 pages, 4 figure

Hall noise and transverse freezing in driven vortex lattices

We study driven vortices lattices in superconducting thin films. Above the critical force $F_c$ we find two dynamical phase transitions at $F_p$ and $F_t$, which could be observed in simultaneous noise measurements of the longitudinal and the Hall voltage. At $F_p$ there is a transition from plastic flow to smectic flow where the voltage noise is isotropic (Hall noise = longitudinal noise) and there is a peak in the differential resistance. At $F_t$ there is a sharp transition to a frozen transverse solid where the Hall noise falls down abruptly and vortex motion is localized in the transverse direction.Comment: 4 pages, 3 figure