Features of the Alvarado score and heel drop test in assessing acute appendicitis.

<p>Features of the Alvarado score and heel drop test in assessing acute appendicitis.</p

Clinical Importance of the Heel Drop Test and a New Clinical Score for Adult Appendicitis

<div><p>Objective</p><p>We tried to evaluate the accuracy of the heel drop test in patients with suspected appendicitis and tried to develop a new clinical score, which incorporates the heel drop test and other parameters, for the diagnosis of this condition.</p><p>Methods</p><p>We performed a prospective observational study on adult patients with suspected appendicitis at two academic urban emergency departments between January and August 2015. The predictive characteristics of each parameter, along with heel drop test results were calculated. A composite score was generated by logistic regression analysis. The performance of the generated score was compared to that of the Alvarado score.</p><p>Results</p><p>Of the 292 enrolled patients, 165 (56.5%) had acute appendicitis. The heel drop test had a higher predictive value than rebound tenderness. Variables and their points included in the new (MESH) score were pain migration (2), elevated white blood cell (WBC) >10,000/μL (3), shift to left (2), and positive heel drop test (3). The MESH score had a higher AUC than the Alvarado score (0.805 vs. 0.701). Scores of 5 and 11 were chosen as cut-off values; a MESH score ≥5 compared to an Alvarado score ≥5, and a MESH score ≥8 compared to an Alvarado score ≥7 showed better performance in diagnosing appendicitis.</p><p>Conclusion</p><p>MESH (migration, elevated WBC, shift to left, and heel drop test) is a simple clinical scoring system for assessing patients with suspected appendicitis and is more accurate than the Alvarado score. Further validation studies are needed.</p></div

Features of the Alvarado score and heel drop test in assessing acute appendicitis.

<p>Features of the Alvarado score and heel drop test in assessing acute appendicitis.</p

Development of the MESH score.

<p>Development of the MESH score.</p

Demographic and clinical data for the study population.

<p>Demographic and clinical data for the study population.</p

Performance of the MESH score and the Alvarado score according to gender^*.

<p>Performance of the MESH score and the Alvarado score according to gender^{<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0164574#t005fn001" target="_blank">*</a>}.</p

Receiver operating characteristic (ROC) curve analysis for the MESH score and the Alvarado score.

<p><i>MESH</i> Migration, Elevated WBC, Shift to left, and Heel drop test; <i>AUC</i> area under ROC curve; <i>CI</i> confidence interval.</p