Accuracy and Mechanical Properties of Open-Cell Microstructures Fabricated by Selective Laser Sintering

This paper investigates the applicability of selective laser sintering (SLS) for the manufacture of scaffold geometries for bone tissue engineering applications. Porous scaffold geometries with open-cell structure and relative density of 10-60 v% were computationally designed and fabricated by selective laser sintering using polyamide powder. Strut and pore sizes ranging from 0.4 - 1 mm and 1.2 -2 mm are explored. The effect of process parameters on compressive properties and accuracy of scaffolds was examined and outline laser power and scan spacing were identified as significant factors. In general, the designed scaffold geometry was not accurately fabricated on the micron-scale. The smallest successfully fabricated strut and pore size was 0.4 mm and 1.2 mm, respectively. It was found that selective laser sintering has the potential to fabricate hard tissue engineering scaffolds. However the technology is not able to replicate exact geometries on the micron-scale but by accounting for errors resulting from the diameter of the laser and from the manufacturing induced geometrical deformations in different building directions, the exact dimensions of the manufactured scaffolds can be predicted and controlled indirectly, which corresponds favorably with its application in computer aided tissue engineering.Mechanical Engineerin

A Bridge to Challenging Environmental Inequality: Intersectionality, Environmental Justice, and Disaster Vulnerability

This article explores the origins and expansions of environmental justice and disaster vulnerability literature. It proposes an intersectional framework as a tool for bridging these fields of research—fields that have moved forward primarily on parallel, yet rarely overlapping paths. The article explores both practical and theoretical issues that stem from the lack of communication between environmental justice and disaster vulnerability literatures, positing that disaster vulnerabilities exist first as issues of environmental justice. This is followed by a discussion of interlocking systems of oppression, which is critical for understanding the root of inequality in both disaster and environmental justice contexts. Focusing on the environmental oppression that underlies these contexts provides a potential basis to merge and improve these literatures at a critical time of increasing rates of environmental risks and disasters. By utilizing an intersectional framework to merge these areas of research, it is possible to develop a more holistic understanding of environmental harms and disaster vulnerabilities, while encouraging more just and equitable planning, preparedness, response, and recovery activities

SCREENING FOR HEPATITIS C Response from Hepatitis C Trust, BASL, BIA, BVHG, BSG, and BHIVA to article asking whether widespread screening for hepatitis C is justified

This is the peer reviewed published version of the following article: Response from Hepatitis C Trust, BASL, BIA, BVHG, BSG, and BHIVA to article asking whether widespread screening for hepatitis C is justified, which has been published in final form at 10.1136/bmj.h998. This article may be used for non-commercial purposes in accordance with BMJ's Terms and Conditions for Self-Archiving.This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/ by/4.0

Soft X-ray Emission from the Spiral Galaxy NGC 1313

The nearby barred spiral galaxy NGC 1313 has been observed with the PSPC instr- ument on board the ROSAT X-ray satellite. Ten individual sources are found. Three sources (X-1, X-2 and X-3 [SN~1978K]) are very bright (~10^40 erg/s) and are unusual in that analogous objects do not exist in our Galaxy. We present an X-ray image of NGC~1313 and \xray spectra for the three bright sources. The emission from the nuclear region (R ~< 2 kpc) is dominated by source X-1, which is located ~1 kpc north of the photometric (and dynamical) center of NGC~1313. Optical, far-infrared and radio images do not indicate the presence of an active galactic nucleus at that position; however, the compact nature of the \xray source (X-1) suggests that it is an accretion-powered object with central mass M >~ 10^3 Msun. Additional emission (L_X ~ 10^39 erg/s) in the nuclear region extends out to ~2.6 kpc and roughly follows the spiral arms. This emission is from 4 sources with luminosity of several x 10^38 erg/s, two of which are consistent with emission from population I sources (e.g., supernova remnants, and hot interstellar gas which has been heated by supernova remnants). The other two sources could be emission from population II sources (e.g., low-mass \xray binaries). The bright sources X-2 and SN~1978K are positioned in the southern disk of NGC~1313. X-2 is variable and has no optical counterpart brighter than 20.8 mag (V-band). It is likely that it is an accretion-powered object in NGC~1313. The type-II supernova SN~1978K (Ryder \etal 1993) has become extra- ordinarily luminous in X-rays $\sim$13 years after optical maximum.Comment: to appear in 10 Jun 1995 ApJ, 30 pgs uuencoded compressed postscript, 25 pgs of figures available upon request from colbert, whole preprint available upon request from Sandy Shrader ([email protected]), hopefully fixed unknown problem with postscript fil

A SINFONI view of Galaxy Centers: Morphology and Kinematics of five Nuclear Star Formation Rings

We present near-infrared (H- and K-band) integral-field observations of the circumnuclear star formation rings in five nearby spiral galaxies. The data, obtained at the Very Large Telescope with the SINFONI spectrograph, are used to construct maps of various emission lines that reveal the individual star forming regions ("hot spots") delineating the rings. We derive the morphological parameters of the rings, and construct velocity fields of the stars and the emission line gas. We propose a qualitative, but robust, diagnostic for relative hot spot ages based on the intensity ratios of the emission lines Brackett gamma, HeI, and [FeII]. Application of this diagnostic to the data presented here provides tentative support for a scenario in which star formation in the rings is triggered predominantly at two well-defined regions close to, and downstream from, the intersection of dust lanes along the bar with the inner Lindblad resonance.Comment: 45 pages incl. 4 tables and 12 (mostly color) figures. Accepted for publication in AJ. A version with full resolution figures can be obtained at ftp://ftp.rssd.esa.int/pub/tboeker/SINFONI/ms.pd

Threshold of Singularity Formation in the Semilinear Wave Equation

Solutions of the semilinear wave equation are found numerically in three spatial dimensions with no assumed symmetry using distributed adaptive mesh refinement. The threshold of singularity formation is studied for the two cases in which the exponent of the nonlinear term is either $p=5$ or $p=7$. Near the threshold of singularity formation, numerical solutions suggest an approach to self-similarity for the $p=7$ case and an approach to a scale evolving static solution for $p=5$.Comment: 6 pages, 7 figure