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Additional file 1: Figure S1. of X-linked intellectual disability gene CASK regulates postnatal brain growth in a non-cell autonomous manner
Description of mouse lines used and effect of cre expression on floxed CASK gene. Figure S2. CASK deletion from neurons and characterization of female heterozygous mice with neuronspecific CASK deletion. Figure S3. CASK deletion from neurons does not affect cerebellum. Figure S4. Generation of CASK(+/-) heterozygous mutant mice. Figure S5. External granular layer of cerebellum is normal during development of CASK(+/-) heterozygous mutant mice. Figure S6. Characterization of CASK(+/-) heterozygous mutant mice. Figure S7. Schematic diagram depicting cell autonomous and non-cell autonomous reduction in cell numbersas possible cause of microcephaly. Figure S8. Table showing the nucleotide sequences of CASK shRNA used in the study. Figure S9. CASK knockdown using shRNA 690 reduces cellular respiration and proliferation. (PDF 73672 kb