Waist circumference provides an indication of numerous cardiometabolic risk factors in adults with cerebral palsy

This article has been made available through the Brunel Open Access Publishing Fund.Objective: To report the prevalence of cardiometabolic risk factors in a cohort of adults with cerebral palsy (CP) and to investigate the ability of anthropometric measures to predict these factors. Design: Cross-sectional study. Setting: Testing took place in a laboratory setting. Participants: Adults with CP (NZ55; mean age, 37.5 13.3y; Gross Motor Function Classification System levels, IeV) participated in this study. Interventions: Not applicable. Main Outcome Measures: Total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, glucose, insulin, and C-reactive protein levels were measured from a fasting venous blood sample. Insulin resistance was calculated using the Homeostasis Model Assessment (HOMA-IR) index. Blood pressure, body mass index (BMI), waist circumference (WC), waist-hip ratio, and waist-height ratio were also measured. The metabolic syndrome (MetS) was defined according to the 2009 Joint Interim Statement. Results: The prevalence of the MetS was 20.5% in ambulatory adults and 28.6% in nonambulatory adults. BMI was associated with HOMA-IR only (bZ.451; P<.01). WC was associated with HOMA-IR (bZ.480; P<.01), triglycerides (bZ.450; P<.01), and systolic blood pressure (bZ.352; P<.05). Receiver operating characteristic curve analysis revealed that WC provided the best indication of hypertensive blood pressure, dyslipidemia, HOMA-IR, and the presence of multiple risk factors (area under the curve, .713e.763). Conclusions: A high prevalence of the MetS was observed in this relatively young sample of adults with CP. WC was a better indicator of a number of risk factors than was BMI and presents as a clinically useful method of screening for cardiometabolic risk among adults with CP

The R.I.G.A. Golf Protest of 1963 and the role of Providence College\u27s Early Integration

https://digitalcommons.providence.edu/dwc_202C31_2023/1006/thumbnail.jp

Toward Supergravity Spectral Action

A spectral action of Euclidean supergravity is proposed. We calculate up to $a_4$, the Seeley-Dewitt coefficients in the expansion of the spectral action associated to the supergravity Dirac operator. This is possible because in simple supergravity, as in pure gravity, a well defined and mathematically consistent Dirac operator can be constructed.Comment: 10pages, no figures, matches published versio

A non-perturbative study of the action parameters for anisotropic-lattice quarks

A quark action designed for highly anisotropic lattice simulations is discussed. The mass-dependence of the parameters in the action is studied and the results are presented. Applications of this action in studies of heavy quark quantities are described and results are presented from simulations at an anisotropy of six, for a range of quark masses from strange to bottom.Comment: 9 pages, 8 figure

The spectral content of SDO/AIA 1600 and 1700 \AA\ filters from flare and plage observations

The strong enhancement of the ultraviolet emission during solar flares is usually taken as an indication of plasma heating in the lower solar atmosphere caused by the deposition of the energy released during these events. Images taken with broadband ultraviolet filters by the {\em Transition Region and Coronal Explorer} (TRACE) and {\em Atmospheric Imaging Assembly} (AIA 1600 and 1700~\AA) have revealed the morphology and evolution of flare ribbons in great detail. However, the spectral content of these images is still largely unknown. Without the knowledge of the spectral contribution to these UV filters, the use of these rich imaging datasets is severely limited. Aiming to solve this issue, we estimate the spectral contributions of the AIA UV flare and plage images using high-resolution spectra in the range 1300 to 1900~\AA\ from the Skylab NRL SO82B spectrograph. We find that the flare excess emission in AIA 1600~\AA\ is { dominated by} the \ion{C}{4} 1550~\AA\ doublet (26\%), \ion{Si}{1} continua (20\%), with smaller contributions from many other chromospheric lines such as \ion{C}{1} 1561 and 1656~\AA\ multiplets, \ion{He}{2} 1640~\AA, \ion{Si}{2} 1526 and 1533~\AA. For the AIA 1700~\AA\ band, \ion{C}{1} 1656~\AA\ multiplet is the main contributor (38\%), followed by \ion{He}{2} 1640 (17\%), and accompanied by a multitude of other, { weaker} chromospheric lines, with minimal contribution from the continuum. Our results can be generalized to state that the AIA UV flare excess emission is of chromospheric origin, while plage emission is dominated by photospheric continuum emission in both channels.Comment: Accepted for publication in ApJ Skylab NRL SO82B data used in this work available at http://dx.doi.org/10.5525/gla.researchdata.68

Influence of shear stress in perfusion bioreactor cultures for the development of three-dimensional bone tissue constructs: a review.

Bone tissue engineering aims to generate clinically applicable bone graft substitutes in an effort to ease the demands and reduce the potential risks associated with traditional autograft and allograft bone replacement procedures. Biomechanical stimuli play an important role under physiologically relevant conditions in the normal formation, development, and homeostasis of bone tissue--predominantly, strain (predicted levels in vivo for humans \u3c2000\u3eμε) caused by physical deformation, and fluid shear stress (0.8-3 Pa), generated by interstitial fluid movement through lacunae caused by compression and tension under loading. Therefore, in vitro bone tissue cultivation strategies seek to incorporate biochemical stimuli in an effort to create more physiologically relevant constructs for grafting. This review is focused on collating information pertaining to the relationship between fluid shear stress, cellular deformation, and osteogenic differentiation, providing further insight into the optimal culture conditions for the creation of bone tissue substitutes

Quantum bounds for gravitational de Sitter entropy and the Cardy-Verlinde formula

We analyze different types of quantum corrections to the Cardy-Verlinde entropy formula in a Friedmann-Robertson-Walker universe and in an (anti)-de Sitter space. In all cases we show that quantum corrections can be represented by an effective cosmological constant which is then used to redefine the parameters entering the Cardy-Verlinde formula so that it becomes valid also with quantum corrections, a fact that we interpret as a further indication of its universality. A proposed relation between Cardy-Verlinde formula and the ADM Hamiltonian constraint is given.Comment: LaTeX file, 15 pages, reference is adde