569 research outputs found
The Influence of Organizational Learning Culture on IT Decision Practices and Acquisition Decisions
Information technology has been described as a facilitator of organizational learning, especially through its use in managing and disseminating organizational knowledge. This research seeks to demonstrate an empirical relationship between organizations that have a continuous learning culture and the technologies they have acquired. Furthermore, it is proposed that the processes by which technology acquisition decisions are made significantly differ in organizations with a strong learning culture from those organizations without such a culture. The hypotheses proposed by this research will be tested from data collected by a national sample survey
Information Systems and Healthcare XXXVI: Building and Maintaining Social Capital–Evidence from the Field
This study investigates how social capital is built and maintained in a Hybrid Virtual Communities (HVC), that is, a group of people with shared interests who meet face-to-face to exchange information and knowledge or provide emotional support and also do so in a “virtual” or online environment. Past health-IS research has primarily focused on pure virtual environments; however, many communities entail face-to-face interactions as well. This research helps fill this void. Discourse analysis of virtual interactions, face-to-face (FTF) observations, and semi-structured interviews of a patient-oriented HVC were analyzed, providing rich descriptive data. Using the theoretical foundation of social capital, this article extends existing theory by combining Drentea and Moren-Cross’s [2005] social support framework with Etzioni and Etzioni’s [1999] aspects of community framework to better explain building and maintaining social capital in a HVC
Better Safe than Sorry: A Conceptual Framework for the Use of the Cloud
Cloud computing has come to stay and is expanding rapidly. The mode of deployment of services has implications for users who store data in the cloud and risk exposure to potentially severeconsequences. The safe use of cloud computing services is therefore necessitated. Drawing on the principle of self-preservation and the theory of protection motivation, this paper develops a conceptual framework for the safe use of cloud computing services by individuals
Facebook’s Use in Higher Education
Social networking sites have experienced explosive growth and they have been integrated into the daily lives of many people. While the majority of college-aged students interact on Facebook every day, both research and implementation of Facebook as a pedagogical tool in the higher education classroom is lacking. This research-in-progress study investigates the question, “How can Facebook can be used to enhance educational experiences beyond that of the traditional classroom?” To do so, students from a southwestern university will participate in a multi-round Delphi study. By generating and ranking ideas directly from students, the results will have content validity and may uncover interesting and state-of-the-art ideas. The results will be available for presentation at the conference
An alternative methodology for a quantitative flow-based cell-mediated in vitro cytotoxicity assay to evaluate immune cell potency
In vitro cytotoxicity assays have a crucial role in determining the functionality and potency levels of various immune cells, including both NK and T-cells. A flow cytometry based cytoxicity assay is commonly used to measure the levels of cell-mediated killing of a target cancer cell. The assay involves staining the cancer cells along with a co-culture incubation step. The cytotoxicity value is typically reported as a percentage killing efficiency of the target cancer cell at a fixed effector-to-target ratio. In vitro cytotoxicity assays have commonly been used to provide valuable potency data and have many diverse applications for multiple cell types.
We propose an alternative assay methodology which can improve accuracy over traditional cytotoxicity analysis methods. This new reporting method/approach can overcome signal saturation issues and allows for more consistent and meaningful outputs over a broader dynamic assay range. It also eliminates any potential extrapolation needed during analysis. This new method provides a means for a more robust cytotoxicity assay, resulting in a more valuable measuring tool
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