CJ Keller et al (2014): Corticocortical evoked potentials reveal projectors and integrators in human brain networks.

Talk given as part of Neuroimaging Statistics Research at Warwick seminars on 19 February 2015

Scaling up Directed Graph Models for Resting-State fMRIwith Stepwise Regression

Poster submitted to the 2016 Organization for Human Brain Mapping (OHBM) in Geneva, 26-30 June

Dynamic Effective Connectivity Modelling with Multiregression Dynamic Models

Poster submitted to the 2015 Organization for Human Brain Mapping (OHBM) in Hawaii, 14-18 June

Results of the machine learning analysis.

<p>Shown here are the ROC curve Area-Under-Curve (AUC) scores, sensitivities and specificities for three classification algorithms. The values are computed using a leave-one-out cross-validation. The 95% confidence intervals are shown in brackets. The sensitivities and specificities are determined from the ROC curve, selecting in each case a threshold that gives good values for both.</p><p>Results of the machine learning analysis.</p

Tissue Transglutamase (TTG) titres at time of specimen collection and Marsh scores at diagnosis.

<p>*HLADQ2+.</p><p>N.B. 2 patients did not have their Marsh scores available, both were established on long term gluten free diets and had a tTG titre of <1 kU/L at the time of urine collection.</p><p>Tissue Transglutamase (TTG) titres at time of specimen collection and Marsh scores at diagnosis.</p

Scatter plot of TTG serology vs classification probability for Coeliac cases.

<p>The classification probabilities are the probability of a given patient having Coeliac disease, as determined by the sparse logistic regression algorithm. The overall correlation of these points is 0.28. One outlying point with TTG>60 kU/L has been removed.</p

Section of mass spectrum corresponding to unique GC peaks.

<p>Peak at mass of 104, which corresponds to the C₈H₈ structure. Peaks at mass 78, 63, 51 and 40 very likely correspond to C₆H_6, C₅H3, C₄H₃, and C₃H₃ respectively; these are all common fragmentations seen to come from cyclooctatetraene. Peak at mass 44 is a common base peak for many organic compounds, including cyclooctatetraene.</p

Section of coeliac disease sample chromatogram showing unique peak.

<p>Section of coeliac disease sample chromatogram showing unique peak.</p

Demographic data of subjects.

<p>Demographic data of subjects.</p

Predicted probability of coeliac disease and Marsh scores at diagnosis.

<p>*HLADQ2+.</p><p>N.B. two patients did not have their Marsh scores available.</p><p>Predicted probability of coeliac disease and Marsh scores at diagnosis.</p