1 research outputs found
Isocyanide-Based Multicomponent Bicyclization with Substituted Allenoate and Isatin: Synthesis of Unusual Spirooxindole Containing [5.5]-Fused Heterocycle
A three-component
bicyclization reaction of isocyanide, substituted
allenoate, and isatin has been disclosed. This protocol is proposed
to proceed through Michael addition, double cyclization, and [1,5]-hydride
shift sequence, thus leading to the formation of two new rings and
five new chemical bonds, including C–C, C–O, and C–N
bonds