Rumpel-Leede phenomenon in a hypertensive patient due to mechanical trauma: a case report.

In this report, we present an interesting case of a patient with Rumpel-Leede phenomenon, a rare occurrence that can result in significant delays in medical treatment. This phenomenon is characterized by the presence of a petechial rash that results from acute dermal capillary rupture. In our patient, it occurred secondary to raised pressure in the dermal vessels caused by repeated inflation of a sphygmomanometer cuff. Contributory factors in Rumpel-Leede phenomenon include prevalent conditions such as diabetes mellitus, hypertension, thrombocytopenia, chronic steroid use, antiplatelets, and anticoagulants.A 58-year-old Russian woman with diabetes and hypertension presented to our hospital with a non-ST elevation myocardial infarction, and she subsequently developed a petechial rash on her distal upper limbs. A vasculitic screen was performed, with normal results.Given the timing and distribution of the rash, it was felt that this was an example of Rumpel-Leede phenomenon in a susceptible individual. This is an important diagnosis to be aware of in patients with vascular risk factors presenting for acute medical care who subsequently develop a petechial rash

Ohiowa Soldier

Describes the Civil War career of John W. Rumpel, with extensive quotations from his diary and letters

Ohiowa Soldier

Describes the Civil War career of John W. Rumpel, with extensive quotations from his diary and letters

Long-term weight loss effects on all cause mortality in overweight/obese populations

This systematic review assesses the long-term effectiveness of weight loss on all cause mortality in overweight/obese people. Medline, Embase and Cinahl were searched (1966–2005). Cohort studies and trials on participants with Body Mass Index ¡Ý25 kg/m2, with weight change and mortality with ¡Ý 2 years follow-up were included finally identifying 11 papers based on 8 studies. There may be gender differences in the benefits for all cause mortality. The impact of weight loss in men on mortality was not clear with some studies indicating weight loss to be detrimental, while a recent cohort study showed benefits, if it were a personal decision. Other studies with no gender separation had similarly mixed results. However, one study indicated that overweight/obese women with obesity related illness, who lost weight intentionally within one year, had significantly reduced mortality rates of 19% -25%. In contrast, studies of overweight/obese diabetics irrespective of gender, showed significant benefit of intentional weight loss on mortality in a metaanalysis, HR=0.75(0.67- 0.83). There is some evidence that intentional weight loss has long-term benefits on all cause mortality for women and more so for diabetics. Long-term effects especially for men are not clear and need further investigation.National Health Service (NHS) R&D Health Technology Assessment Board

Spatial patterns of knowledge-intensive business services in cities of various sizes, morphologies and economies

We compare intra-urban localization patterns of advertising and IT companies in three large Czech cities. The main aim of our analysis is an empirically-based contribution to the question to what extent do knowledge bases affect the spatial distribution of various knowledge-intensive business industries. The central research question is: To what extent is the localization of these two industries influenced by different modes of innovation/knowledge bases (symbolic vs. synthetic) and to what extent by contextual factors, such as urban size, morphology, position in the urban hierarchy and economic profile of the given city. We found that the urban contexts shape the localization patterns of advertising and IT companies more than differences in knowledge bases-both industries cluster primarily in the inner cities and urban cores. Formation of more suburban IT "scientific neighborhoods" is limited.Web of Science125art. no. 184

Constructing Regional Advantage: Does it matter for Czech regions?

Innovation and competitiveness are two concepts which govern the national and regional policies throughout the world. Innovation is the key driver of global economic competitiveness. Regions are considered a key level where innovation processes are shaped, coordinated and governed through localized capabilities. While until recently competitiveness of economies was developed from comparative or competitive advantages, in the era of knowledge economy the new theory of constructed advantage allows for more attention to the role and impact of the public sector and public-private partnership in the economy, based upon the dimensions related and unrelated variety and differentiated knowledge bases. The key to the constructed advantage is regional innovation systems approach. The introduction to the new theory is explained in the paper in the view of European collaborative research project and the first assessment of how policies for constructing regional advantage can work within the environment of specific regions of the Czech Republic is proposed.Regional innovation system; comparative, competitive and constructed advantage; related and unrelated varieties; differentiated knowledge bases

Lignin biomarkers as tracers of mercury sources in lakes water column

This study presents the role of specific terrigenous organic compounds as important vectors of mercury (Hg) transported from watersheds to lakes of the Canadian boreal forest. In order to differentiate the autochthonous from the allochthonous organic matter (OM), lignin derived biomarker signatures [Lambda, S/V, C/V, P/(V ? S), 3,5-Bd/V and (Ad/Al)v] were used. Since lignin is exclusively produced by terrigenous plants, this approach can give a non equivocal picture of the watershed inputs to the lakes. Moreover, it allows a characterization of the source of OM and its state of degradation. The water column of six lakes from the Canadian Shield was sampled monthly between June and September 2005. Lake total dissolved Hg concentrations and Lambda were positively correlated, meaning that Hg and ligneous inputs are linked (dissolved OM r2 = 0.62, p\0.0001; particulate OM r2 = 0.76, p\0.0001). Ratios of P/(V ? S) and 3,5-Bd/V from both dissolved OM and particulate OM of the water column suggest an inverse relationship between the progressive state of pedogenesis and maturation of the OM in soil before entering the lake, and the Hg concentrations in the water column. No relation was found between Hg levels in the lakes and the watershed flora composition—angiosperm versus gymnosperm or woody versus non-woody compounds. This study has significant implications for watershed management of ecosystems since limiting fresh terrestrial OM inputs should reduce Hg inputs to the aquatic systems. This is particularly the case for largescale land-use impacts, such as deforestation, agriculture and urbanization, associated to large quantities of soil OM being transferred to aquatic systems

Territorial marketing in the Czech Republic: a trial – and – error process

There are numerous obscurities connected with territorial marketing. Substantial misunderstandings can occur already for the sake of the fact that this concept was labeled by different notions so far. Naturally, the same – with even higher intensity – holds true for the transition economies. This paper focuses upon the practice of territorial marketing in the Czech Republic. As it is shown, there is rather spontaneous than planned development of this concept in the Czech space. At the same time, there exists sufficient room for future application of selected components of territorial marketing in this country.territorial marketing, local/regional development, Czech Republic, basic categories of territorial marketing