Toward a multi-level strategy to reduce stigma in global mental health: overview protocol of the Indigo Partnership to develop and test interventions in low- and middle-income countries

There is increasing attention to the impacts of stigma and discrimination related to mental health on quality of life and access to and quality of healthcare. Effective strategies for stigma reduction exist, but most evidence comes from high-income settings. Recent reviews of stigma research have identified gaps in the field, including limited cultural and contextual adaptation of interventions, a lack of contextual psychometric information on evaluation tools, and, most notably, a lack of multi-level strategies for stigma reduction. The Indigo Partnership research programme will address these knowledge gaps through a multi-country, multi-site collaboration for anti-stigma interventions in low- and middle-income countries (LMICs) (China, Ethiopia, India, Nepal, and Tunisia). The Indigo Partnership aims to: 1) carry out research to strengthen the understanding of mechanisms of stigma processes and reduce stigma and discrimination against people with mental illness in LMICs; and 2) establish a strong collaborative research consortium through the conduct of this programme. Specifically, the Indigo Partnership involves developing and pilot testing anti-stigma interventions at the community, primary care, and mental health specialist care levels, with a systematic approach to cultural and contextual adaptation across the sites. This work also involves transcultural translation and adaptation of stigma and discrimination measurement tools. The Indigo Partnership operates with the key principle of partnering with people with lived experience of mental illness for the development and implementation of the pilot interventions, as well as capacity building and cross-site learning to actively develop a more globally representative and equitable mental health research community. This work is envisioned to have a long-lasting impact, both in terms of the capacity building provided to participating institutions and researchers, and the foundation it provides for future research to extend the evidence base of what works to reduce and ultimately end stigma and discrimination in mental health

The high-resolution map of Oxia Planum, Mars; the landing site of the ExoMars Rosalind Franklin rover mission

This 1:30,000 scale geological map describes Oxia Planum, Mars, the landing site for the ExoMars Rosalind Franklin rover mission. The map represents our current understanding of bedrock units and their relationships prior to Rosalind Franklin’s exploration of this location. The map details 15 bedrock units organised into 6 groups and 7 textural and surficial units. The bedrock units were identified using visible and near-infrared remote sensing datasets. The objectives of this map are (i) to identify where the most astrobiologically relevant rocks are likely to be found, (ii) to show where hypotheses about their geological context (within Oxia Planum and in the wider geological history of Mars) can be tested, (iii) to inform both the long-term (hundreds of metres to ∼1 km) and the short-term (tens of metres) activity planning for rover exploration, and (iv) to allow the samples analysed by the rover to be interpreted within their regional geological context

Loss of Ceres' Icy Shell from Impacts: Assessment and Implications

International audienceDawn observations revealed Ceres' outer shell is dominated by rock, not ice. We model the removal of a 50 km ice shell via impact-induced sublimation

Loss of Ceres' Icy Shell from Impacts: Assessment and Implications

International audienceDawn observations revealed Ceres' outer shell is dominated by rock, not ice. We model the removal of a 50 km ice shell via impact-induced sublimation

Loss of Ceres' Icy Shell from Impacts: Assessment and Implications

International audienceDawn observations revealed Ceres' outer shell is dominated by rock, not ice. We model the removal of a 50 km ice shell via impact-induced sublimation

Study protocol of a randomized controlled trial evaluating home treatment with peer support for acute mental health crises (HoPe)

Background: Home treatment (HT) is a treatment modality for patients with severe mental illness (SMI) in acute mental crises. It is frequently considered equivalent to psychiatric inpatient treatment in terms of treatment outcome. Peer Support (PS) means that people with lived experience of a mental illness are trained to support others on their way towards recovery. While PS is growing in international importance and despite a growing number of studies supporting its benefits, it is still not comprehensively implemented into routine care. The HoPe (Home Treatment with Peer Support) study investigates a combination of both - HT and PS - to provide further evidence for a recovery-oriented treatment of psychiatric patients. Methods: In our randomized controlled trial (RCT), HT with PS is compared with HT without PS within a network of eight psychiatric clinical centers from the North, South and East of Germany. We investigate the effects of a combination of both approaches with respect to the prevention of relapse/recurrence defined as first hospitalization after randomization (primary outcome), disease severity, general functioning, self-efficacy, psychosocial health, stigma resistance, recovery support, and service satisfaction (secondary outcomes). A sample of 286 patients will be assessed at baseline after admission to HT care (data point t(0)) and randomized into the intervention (HT+ PS) and control arm (HT). Follow-Up assessments will be conducted 2, 6 and 12 months after admission (resulting in three further data points, t(1) to t(3)) and will be analyzed via intention-to-treat approach. Discussion: This study may determine the positive effects of PS added to HT, prove additional evidence for the efficacy of PS and thereby facilitate its further implementation into psychiatric settings. The aim is to improve quality of mental health care and patients' recovery as well as to reduce the risk of relapses and hospitalizations for patients with SMI

The high-resolution map of Oxia Planum, Mars; the landing site of the ExoMars Rosalind Franklin rover mission

International audienceThis 1:30,000 scale geological map describes Oxia Planum, Mars, the landing site for theExoMars Rosalind Franklin rover mission. The map represents our current understanding ofbedrock units and their relationships prior to Rosalind Franklin’s exploration of this location.The map details 15 bedrock units organised into 6 groups and 7 textural and surficial units.The bedrock units were identified using visible and near-infrared remote sensing datasets.The objectives of this map are (i) to identify where the most astrobiologically relevant rocksare likely to be found, (ii) to show where hypotheses about their geological context (withinOxia Planum and in the wider geological history of Mars) can be tested, (iii) to inform boththe long-term (hundreds of metres to ∼1 km) and the short-term (tens of metres) activityplanning for rover exploration, and (iv) to allow the samples analysed by the rover to beinterpreted within their regional geological context