The shape of things to come? Expanding the inequality and grievance model for civil war forecasts with event data

© The Author(s) 2017. We examine if dynamic information from event data can help improve on a model attempting to forecast civil war using measures reflecting plausible motivation and grievances. Buhaug, Cederman, and Gleditsch predict the risk of civil war using a horizontal inequality model with measures reflecting motivation and relevant group characteristics at the country level. The predictions from their model outperform in an out-of-sample forecast conventional countrylevel models of civil war, emphasizing vertical inequality and country characteristics. However, most grievance measures change little over time. We surmise that a model reflecting potential motivation for conflict can be improved with more dynamic information on mobilization and the behavior of actors. Our conjecture receives some support in the empirical analysis, where we consider both conflict onset and termination over territorial and governmental incompatibilities in the Uppsala/PRIO Armed Conflict Data, and find some evidence that event data can help improve forecasts. Moreover, models with the original grievance measures do better than purely event based models, supporting our claim that both structure and event based components can add value to conflict prediction models. However, the contribution of events to improving predictive power is modest and not entirely consistent, and some types of conflict events seem easier to forecast than others

Confrontational Behavior and Escalation to War 1816-1980: A Research Plan

The understanding of international war, like many complex social events, may be - and has been - ap proached from a range of theoretical perspectives and via a variety of research strategies. Outside of the work of Bloch (1898), Sorokin (1936), Richardson (1941), and Wright (1942), however, there was little re search of a scientific nature until the mid-1960s. And while these past fifteen years have certainly not given us a compelling theory of international war, they have seen a steady growth in cumulative knowledge regar ding the correlates of war. These results, despite the expected mix of inconsistencies and anomalies, provide us with some sense of the factors that are most consistently associated with war over the last century and a half, along with some tentative insights into the rising and declining potency of these factors.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68556/2/10.1177_002234338201900104.pd

Identification of six new susceptibility loci for invasive epithelial ovarian cancer.

Genome-wide association studies (GWAS) have identified 12 epithelial ovarian cancer (EOC) susceptibility alleles. The pattern of association at these loci is consistent in BRCA1 and BRCA2 mutation carriers who are at high risk of EOC. After imputation to 1000 Genomes Project data, we assessed associations of 11 million genetic variants with EOC risk from 15,437 cases unselected for family history and 30,845 controls and from 15,252 BRCA1 mutation carriers and 8,211 BRCA2 mutation carriers (3,096 with ovarian cancer), and we combined the results in a meta-analysis. This new study design yielded increased statistical power, leading to the discovery of six new EOC susceptibility loci. Variants at 1p36 (nearest gene, WNT4), 4q26 (SYNPO2), 9q34.2 (ABO) and 17q11.2 (ATAD5) were associated with EOC risk, and at 1p34.3 (RSPO1) and 6p22.1 (GPX6) variants were specifically associated with the serous EOC subtype, all with P < 5 × 10(-8). Incorporating these variants into risk assessment tools will improve clinical risk predictions for BRCA1 and BRCA2 mutation carriers.COGS project is funded through a European Commission's Seventh Framework Programme grant (agreement number 223175 ] HEALTH ]F2 ]2009 ]223175). The CIMBA data management and data analysis were supported by Cancer Research.UK grants 12292/A11174 and C1287/A10118. The Ovarian Cancer Association Consortium is supported by a grant from the Ovarian Cancer Research Fund thanks to donations by the family and friends of Kathryn Sladek Smith (PPD/RPCI.07). The scientific development and funding for this project were in part supported by the US National Cancer Institute GAME ]ON Post ]GWAS Initiative (U19 ]CA148112). This study made use of data generated by the Wellcome Trust Case Control consortium. Funding for the project was provided by the Wellcome Trust under award 076113. The results published here are in part based upon data generated by The Cancer Genome Atlas Pilot Project established by the National Cancer Institute and National Human Genome Research Institute (dbGap accession number phs000178.v8.p7). The cBio portal is developed and maintained by the Computational Biology Center at Memorial Sloan ] Kettering Cancer Center. SH is supported by an NHMRC Program Grant to GCT. Details of the funding of individual investigators and studies are provided in the Supplementary Note. This study made use of data generated by the Wellcome Trust Case Control consortium, funding for which was provided by the Wellcome Trust under award 076113. The results published here are, in part, based upon data generated by The Cancer Genome Atlas Pilot Project established by the National Cancerhttp://dx.doi.org/10.1038/ng.3185This is the Author Accepted Manuscript of 'Identification of six new susceptibility loci for invasive epithelial ovarian cancer' which was published in Nature Genetics 47, 164–171 (2015) © Nature Publishing Group - content may only be used for academic research

Deconstructing the enduring appeal of the Third Reich

One of the interesting aspects of contemporary culture has been the continuing appeal of the Third Reich (1933-1945) in the modern imagination and this essay examines reasons for this continuing appeal. It is suggested that the reasons for this continuing appeal are complex, although possibly include: 1) the aesthetic and audio-visual nature of the regime, 2) the general appeal of a militaristic society, 3) technological achievements during the regime, 4) the historical idiosyncrasy of the regime, and 5) the discourse of tragedy which can be applied to the regime. The essay concludes with an attempt to examine the implications of the appeal of the Third Reich for the task of education for peace