Hotelier Attitudes toward Sustainability in Virginia Beach

This study examined Virginia Beach hoteliers’ knowledge surrounding sustainable tourism, awareness of sustainable programs offered both on the local and national levels, and evaluation of the current sustainable programs available in Virginia Beach. The Virginia Beach Convention & Visitors Bureau distributed a sustainability-focused survey to the General Managers of all hotels in Virginia Beach city limits. With the various programs available and limited success to this point, it is imperative to get hoteliers involved in order to continue to work toward Virginia Beach’s vision of being a sustainable destination. In order for Virginia Beach to continue to position itself as a premier sustainable destination, its leaders must educate their hoteliers of the programs available in order to increase engagement

Miscellany

Art Literature Roy F. Powell Creditshttps://digitalcommons.georgiasouthern.edu/miscell/1001/thumbnail.jp

Hotelier Attitudes toward Sustainability in Virginia Beach

previously providedThis study examined Virginia Beach hoteliers’ knowledge surrounding sustainable tourism, awareness of sustainable programs offered both on the local and national levels, and evaluation of the current sustainable programs available in Virginia Beach. The Virginia Beach Convention & Visitors Bureau distributed a sustainability-focused survey to the General Managers of all hotels in Virginia Beach city limits. With the various programs available and limited success to this point, it is imperative to get hoteliers involved in order to continue to work toward Virginia Beach’s vision of being a sustainable destination. In order for Virginia Beach to continue to position itself as a premier sustainable destination, its leaders must educate their hoteliers of the programs available in order to increase engagement

Expression of renal cell markers and detection of 3p loss links endolymphatic sac tumor to renal cell carcinoma and warrants careful evaluation to avoid diagnostic pitfalls

Abstract Endolymphatic sac tumor (ELST) is a rare neoplasm arising in the temporal petrous region thought to originate from endolymphatic sac epithelium. It may arise sporadically or in association with Von-Hippel-Lindau syndrome (VHL). The ELST prevalence in VHL ranges from 3 to 16% and may be the initial presentation of the disease. Onset is usually in the 3rd to 5th decade with hearing loss and an indolent course. ELSTs present as locally destructive lesions with characteristic computed tomography imaging features. Histologically, they show papillary, cystic or glandular architectures. Immunohistochemically, they express keratin, EMA, and variably S100 and GFAP. Currently it is recommended that, given its rarity, ELST needs to be differentiated from other entities with similar morphologic patterns, particularly other VHL-associated neoplasms such as metastatic clear cell renal cell carcinoma (ccRCC). Nineteen ELST cases were studied. Immunohistochemistry (18/19) and single nucleotide polymorphism microarray testing was performed (12/19). Comparison with the immunophenotype and copy number profile in RCC is discussed. Patients presented with characteristic bone destructive lesions in the petrous temporal bones. Pathology of tumors showed characteristic ELST morphology with immunoexpression of CK7, GFAP, S100, PAX-8, PAX-2, CA-9 in the tumor cells. Immunostaines for RCC, CD10, CK20, chromogranin A, synaptophysin, TTF-1, thyroglobulin, and transthyretin were negative in the tumor cells. Molecular testing showed loss of 3p and 9q in 66% (8/12) and 58% (7/12) cases, respectively. Immunoreactivity for renal markers in ELST is an important diagnostic caveat and has not been previously reported. In fact, renal markers are currently recommended in order to rule out metastatic RCC although PAX gene complex and CA-9 have been implicated in the development of the inner ear. Importantly copy number assessment of ELST has not been previously reported. Loss of 3p (including the VHL locus) in ELST suggests similar mechanistic origins as ccRCC