16 research outputs found
Contracepção Hormonal segundo a Ótica do Estudante de Medicina: Mais um Desafio para o Ensino Médico Brasileiro?
Clamp loader ATPases and the evolution of DNA replication machinery
Clamp loaders are pentameric ATPases of the AAA+ family that operate to ensure processive DNA replication. They do so by loading onto DNA the ring-shaped sliding clamps that tether the polymerase to the DNA. Structural and biochemical analysis of clamp loaders has shown how, despite differences in composition across different branches of life, all clamp loaders undergo the same concerted conformational transformations, which generate a binding surface for the open clamp and an internal spiral chamber into which the DNA at the replication fork can slide, triggering ATP hydrolysis, release of the clamp loader, and closure of the clamp round the DNA. We review here the current understanding of the clamp loader mechanism and discuss the implications of the differences between clamp loaders from the different branches of life
Association between college health services and contraceptive use among female students at five colleges in Wuhan, China: a cross-sectional study
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Pubic Hair Grooming Prevalence and Motivation Among Women in the United States (vol 152, pg 1106, 2016)
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