4,274 research outputs found
Cloning, sequencing, and characterization of the hexahydro-1,3,5-trinitro-1,3,5-triazine degradation gene cluster from Rhodococcus rhodochrous
Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) is a high explosive which presents an environmental hazard as a major land and groundwater contaminant. Rhodococcus rhodochrous strain 11Y was isolated from explosive contaminated land and is capable of degrading RDX when provided as the sole source of nitrogen for growth. Products of RDX degradation in resting-cell incubations were analyzed and found to include nitrite, formaldehyde, and formate. No ammonium was excreted into the medium, and no dead-end metabolites were observed. The gene responsible for the degradation of RDX in strain 11Y is a constitutively expressed cytochrome P450-like gene, xpLA, which is found in a gene cluster with an adrenodoxin reductase homologue, xplB. The cytochrome P450 also has a flavodoxin domain at the N terminus. This study is the first to present a gene which has been identified as being responsible for RDX biodegradation. The mechanism of action of XplA on RDX is thought to involve initial denitration followed by spontaneous ring cleavage and mineralization
Fredkin Gates for Finite-valued Reversible and Conservative Logics
The basic principles and results of Conservative Logic introduced by Fredkin
and Toffoli on the basis of a seminal paper of Landauer are extended to
d-valued logics, with a special attention to three-valued logics. Different
approaches to d-valued logics are examined in order to determine some possible
universal sets of logic primitives. In particular, we consider the typical
connectives of Lukasiewicz and Godel logics, as well as Chang's MV-algebras. As
a result, some possible three-valued and d-valued universal gates are described
which realize a functionally complete set of fundamental connectives.Comment: 57 pages, 10 figures, 16 tables, 2 diagram
On well-rounded ideal lattices - II
We study well-rounded lattices which come from ideals in quadratic number
fields, generalizing some recent results of the first author with K. Petersen.
In particular, we give a characterization of ideal well-rounded lattices in the
plane and show that a positive proportion of real and imaginary quadratic
number fields contains ideals giving rise to well-rounded lattices.Comment: 13 pages; to appear in the International Journal of Number Theor
Efficient implementation of selective recoupling in heteronuclear spin systems using Hadamard matrices
We present an efficient scheme which couples any designated pair of spins in
heteronuclear spin systems. The scheme is based on the existence of Hadamard
matrices. For a system of spins with pairwise coupling, the scheme
concatenates intervals of system evolution and uses at most pulses
where . Our results demonstrate that, in many systems, selective
recoupling is possible with linear overhead, contrary to common speculation
that exponential effort is always required.Comment: 7 pages, 4 figures, mypsfig2, revtex, submitted April 27, 199
Colloquium: Statistical mechanics of money, wealth, and income
This Colloquium reviews statistical models for money, wealth, and income
distributions developed in the econophysics literature since the late 1990s. By
analogy with the Boltzmann-Gibbs distribution of energy in physics, it is shown
that the probability distribution of money is exponential for certain classes
of models with interacting economic agents. Alternative scenarios are also
reviewed. Data analysis of the empirical distributions of wealth and income
reveals a two-class distribution. The majority of the population belongs to the
lower class, characterized by the exponential ("thermal") distribution, whereas
a small fraction of the population in the upper class is characterized by the
power-law ("superthermal") distribution. The lower part is very stable,
stationary in time, whereas the upper part is highly dynamical and out of
equilibrium.Comment: 24 pages, 13 figures; v.2 - minor stylistic changes and updates of
references corresponding to the published versio
Volume Characteristics of Landslides Triggered by the MW 7.8 2016 Kaikōura Earthquake, New Zealand, Derived From Digital Surface Difference Modeling
We use a mapped landslide inventory coupled with a 2‐m resolution vertical difference model covering an area of 6,875 km2 to accurately constrain landslide volume‐area relationships. We use the difference model to calculate the source volumes for landslides triggered by the MW 7.8 Kaikōura, New Zealand, earthquake of 14 November 2016. Of the 29,519 mapped landslides in the inventory, 28,394 are within the analysis area, and of these, we have calculated the volume of 17,256 source areas that are ≥90% free of debris. Of the 28,394 landslides, about 80% are classified as soil or rock avalanches and the remainder as mainly translational slides. Our results show that both the soil avalanches and the rock avalanches, ignoring their source geology, have area to volume power‐law scaling exponents (γ) of 0.921 to 1.060 and 1.040 to 1.138, respectively. These are lower than the γ values of 1.1–1.3 (for soil) and 1.3–1.6 (for rock) reported in the literature for undifferentiated landslide types. They are, however, similar to those γ values estimated from other coseismic landslide inventories. In contrast, for 50 selected rotational, translational (planar slide surfaces), or compound slides, where much of the debris remains in the source area, we found γ values range between 1.46 and 1.47, indicating that their slide surfaces were considerably deeper than those landslides classified as avalanches. This study, like previous studies on coseismic landslides, shows that soil and rock avalanches (disrupted landslides) are the dominant landslide type triggered by earthquakes and that they tend to be shallow.Key PointsWe use a 2‐m resolution vertical difference model to estimate source volumes for 17,256 landslides with sources ≥90% free of debris triggered by the MW7.8 2016 Kaikōura EarthquakeThe model was derived by subtracting a tectonically adjusted pre‐EQ surface model from a post‐EQ model, covering an area of 6,875 km2Landslide trigger mechanism, type/failure mode, and source material are critical for accurate estimation of landslide volumes from source‐area geometriesPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/156166/2/jgrf21176.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/156166/1/jgrf21176_am.pd
Isothermal Recombinase Polymerase amplification (RPA) of Schistosoma haematobium DNA and oligochromatographic lateral flow detection
© 2015 Rosser et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. The attached file is the published version of the article
Boolean Dynamics with Random Couplings
This paper reviews a class of generic dissipative dynamical systems called
N-K models. In these models, the dynamics of N elements, defined as Boolean
variables, develop step by step, clocked by a discrete time variable. Each of
the N Boolean elements at a given time is given a value which depends upon K
elements in the previous time step.
We review the work of many authors on the behavior of the models, looking
particularly at the structure and lengths of their cycles, the sizes of their
basins of attraction, and the flow of information through the systems. In the
limit of infinite N, there is a phase transition between a chaotic and an
ordered phase, with a critical phase in between.
We argue that the behavior of this system depends significantly on the
topology of the network connections. If the elements are placed upon a lattice
with dimension d, the system shows correlations related to the standard
percolation or directed percolation phase transition on such a lattice. On the
other hand, a very different behavior is seen in the Kauffman net in which all
spins are equally likely to be coupled to a given spin. In this situation,
coupling loops are mostly suppressed, and the behavior of the system is much
more like that of a mean field theory.
We also describe possible applications of the models to, for example, genetic
networks, cell differentiation, evolution, democracy in social systems and
neural networks.Comment: 69 pages, 16 figures, Submitted to Springer Applied Mathematical
Sciences Serie
Metastatic appendiceal adenocarcinoma presenting late as epididymo-orchitis: a case report and review of literature
BACKGROUND: Whereas testicular metastases are in themselves a rare entity, testicular secondaries from an appendiceal carcinoma have not yet been described. The case also illustrates the diagnostic dilemma of a tumour presenting as epididymo-orchitis. CASE PRESENTATION: The authors present a case of an appendiceal carcinoma that, two years after radical therapy, manifested as a secondary in the testis. It was misdiagnosed as an epididymo-orchitis and was only revealed through histology. CONCLUSIONS: Practitioners need to remember that long-standing testicular inflammation may result form secondary tumours. Even "exotic" primary tumours in the medical history of the patient must give rise to an increased suspicion threshold
Quantum Computer with Mixed States and Four-Valued Logic
In this paper we discuss a model of quantum computer in which a state is an
operator of density matrix and gates are general quantum operations, not
necessarily unitary. A mixed state (operator of density matrix) of n two-level
quantum systems is considered as an element of 4^n-dimensional operator Hilbert
space (Liouville space). It allows to use a quantum computer model with
four-valued logic. The gates of this model are general superoperators which act
on n-ququat state. Ququat is a quantum state in a four-dimensional (operator)
Hilbert space. Unitary two-valued logic gates and quantum operations for an
n-qubit open system are considered as four-valued logic gates acting on
n-ququat. We discuss properties of quantum four-valued logic gates. In the
paper we study universality for quantum four-valued logic gates.Comment: 17 page
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